Assay Report Card

Basic Information

ID: ALA5263213

Type: Toxicity

Description: Toxicity in BALB/c nude mouse xenografted with human NCI-H1975 cells harboring EGFR L858R/T790M mutant assessed as body weight loss at 15 to 30 mg/kg, po for 18 days

Organism: Mus musculus

Strain: BALB/c

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
578.525.105.10
591.515.105.10