Assay Report Card

Basic Information

ID: ALA5263216

Type: Functional

Description: Antitumor activity against human NCI-H1975 cells harboring EGFR L858R/T790M mutant xenografted in BALB/c nude mouse assessed as tumor growth inhibition at 15 mg/kg, po for 18 days

Organism: Homo sapiens

Cell type: NCI-H1975

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
578.525.105.10
591.515.105.10