Basic Information
ID: ALA5263283
Type: Binding
Description: Inhibition of BCRP (unknown origin) expressed in dog MDCK-II cells using pheophorbide A as substrate preincubated for 20 mins followed by substrate addition and measured after 120 mins by flow cytometry analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MDCK-II
Target: ATP-binding cassette sub-family G member 2(ALA5393)
Document: ALA5260824
Inhibition of BCRP (unknown origin) expressed in dog MDCK-II cells using pheophorbide A as substrate preincubated for 20 mins followed by substrate addition and measured after 120 mins by flow cytometry analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5263283
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 425.54 | 3.49 | 3.49 |
| 343.43 | 3.43 | 3.43 |
| 416.49 | 2.69 | 2.69 |
| 399.50 | 3.17 | 3.17 |
| 401.52 | 2.79 | 2.79 |
| 424.51 | 3.62 | 3.62 |
| 430.51 | 3.08 | 3.08 |
| 475.60 | 4.39 | 4.39 |
| 359.44 | 2.36 | 2.36 |
| 358.45 | 2.87 | 2.87 |
| 357.46 | 3.48 | 3.48 |
| 347.38 | 2.67 | 2.67 |
| 461.57 | 4.20 | 4.20 |
| 330.40 | 2.83 | 2.83 |
| 387.44 | 3.16 | 3.16 |
| 396.50 | 3.96 | 3.96 |
| 387.49 | 2.40 | 2.40 |
| 390.45 | 2.58 | 2.58 |
| 419.53 | 5.02 | 5.02 |
| 329.41 | 3.44 | 3.44 |
| 376.42 | 2.19 | 2.19 |
| 489.63 | 4.78 | 4.78 |
| 411.51 | 3.48 | 3.48 |