Basic Information
ID: ALA5263287
Type: Binding
Description: Inhibition of P-gp (unknown origin) expressed in dog MDCK-MDR1cells assessed as maximum inhibition at 10 uM by calcein AM accumulation assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MDCK-MDR1
Target: P-glycoprotein 1(ALA4302)
Document: ALA5260824
Inhibition of P-gp (unknown origin) expressed in dog MDCK-MDR1cells assessed as maximum inhibition at 10 uM by calcein AM accumulation assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5263287
Imax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 343.43 | 3.43 | 3.43 |
| 358.45 | 2.87 | 2.87 |
| 347.38 | 2.67 | 2.67 |
| 330.40 | 2.83 | 2.83 |
| 387.44 | 3.16 | 3.16 |
| 396.50 | 3.96 | 3.96 |
| 419.53 | 5.02 | 5.02 |
| 329.41 | 3.44 | 3.44 |