ID: ALA5264189
Type: Binding
Description: Inhibition of human Nav1.7 alpha subunit expressed in HEK293 cells co-expressing beta1 subunit at -60 mV holding potential by whole-cell patch voltage clamp electrophysiology recording
Organism: Homo sapiens
Cell type: HEK293
Bioactivity
Activity Types for Assay ALA5264189
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
415.91 | 3.76 | 3.76 |
399.46 | 3.25 | 3.25 |
335.78 | 2.35 | 2.35 |
433.90 | 3.86 | 3.86 |
397.92 | 3.62 | 3.62 |
431.91 | 2.88 | 2.88 |
377.87 | 3.52 | 3.52 |
409.52 | 3.67 | 3.67 |
421.53 | 3.99 | 3.99 |
432.37 | 4.28 | 4.28 |
349.81 | 2.74 | 2.74 |
349.81 | 2.88 | 2.88 |
451.89 | 4.01 | 4.01 |
457.51 | 4.23 | 4.23 |
395.50 | 3.42 | 3.42 |
405.44 | 3.60 | 3.60 |
469.88 | 4.04 | 4.04 |
431.48 | 4.13 | 4.13 |
449.49 | 3.61 | 3.61 |
445.50 | 4.52 | 4.52 |
435.56 | 4.66 | 4.66 |
477.52 | 5.06 | 5.06 |
363.84 | 3.13 | 3.13 |
369.46 | 3.35 | 3.35 |
365.81 | 1.97 | 1.97 |
459.53 | 4.91 | 4.91 |
423.55 | 4.23 | 4.23 |