Basic Information
ID: ALA5264644
Type: Binding
Description: Protac activity at VHL/AR in AR-positive human LNCaP cells assessed as induction of androgen receptor degradation at 1 uM incubated for 6 hrs by Western blot analysis (Rvb = 0%)
Organism: Homo sapiens
Cell type: LNCaP
Activity Charts
Bioactivity
Activity Types for Assay ALA5264644
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 464.44 | 3.99 | 3.99 |
| 1095.81 | ||
| 1129.84 | ||
| 1136.86 | ||
| 1034.73 | ||
| 1085.81 | ||
| 1097.26 | ||
| 1033.23 | ||
| 1019.20 | ||
| 1087.31 | ||
| 1089.80 | ||
| 1129.84 | ||
| 1129.84 | ||
| 1102.32 | ||
| 1154.35 | ||
| 1114.30 | ||
| 1073.28 | ||
| 1061.28 | ||
| 991.15 | 7.55 | 7.55 |
| 935.04 | 5.99 | 5.99 |
| 1005.17 | ||
| 1101.33 | ||
| 1125.31 | ||
| 949.07 | 6.38 | 6.38 |
| 1023.14 | ||
| 1047.25 | ||
| 1045.23 | ||
| 1115.32 | ||
| 1031.24 | ||
| 977.12 | 7.16 | 7.16 |
| 963.09 | 6.77 | 6.77 |
| 1059.25 | ||
| 1073.28 |