Basic Information
ID: ALA5264682
Type: Binding
Description: Protac activity at VHL/AR in AR-positive human LNCaP cells assessed as induction of androgen receptor degradation at 100 nM preincubated with proteasome inhibitor, MG132 for 2 hrs followed by compound addition and measured after 6 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: LNCaP
Target: VHL/Androgen receptor(ALA4523730)
Document: ALA5260842
Protac activity at VHL/AR in AR-positive human LNCaP cells assessed as induction of androgen receptor degradation at 100 nM preincubated with proteasome inhibitor, MG132 for 2 hrs followed by compound addition and measured after 6 hrs by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5264682
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1129.84 |