Basic Information
ID: ALA5265274
Type: Binding
Description: Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for 30 mins by RapidFire Mass spectrometry
Organism: Rattus norvegicus
Cell type: RBL
Activity Charts
Bioactivity
Activity Types for Assay ALA5265274
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 378.42 | 3.90 | 3.90 |
| 342.44 | 3.30 | 3.30 |
| 330.78 | 1.78 | 1.78 |
| 360.85 | 2.53 | 2.53 |
| 312.37 | 1.48 | 1.48 |
| 386.45 | 3.50 | 3.50 |
| 382.51 | 3.29 | 3.29 |
| 359.82 | 1.50 | 1.50 |
| 343.43 | 2.70 | 2.70 |
| 331.80 | 2.80 | 2.80 |
| 382.51 | 3.29 | 3.29 |
| 387.91 | 4.22 | 4.22 |
| 296.33 | 1.13 | 1.13 |
| 353.47 | 3.57 | 3.57 |
| 311.35 | 0.46 | 0.46 |
| 422.45 | 3.06 | 3.06 |
| 402.93 | 3.55 | 3.55 |
| 345.44 | 3.21 | 3.21 |
| 331.80 | 2.80 | 2.80 |
| 344.42 | 2.09 | 2.09 |
| 325.37 | 0.85 | 0.85 |
| 382.51 | 3.29 | 3.29 |
| 343.43 | 2.70 | 2.70 |
| 369.47 | 2.29 | 2.29 |
| 365.48 | 3.57 | 3.57 |
| 343.43 | 2.70 | 2.70 |
| 297.36 | 2.15 | 2.15 |
| 377.87 | 3.35 | 3.35 |
| 386.47 | 2.85 | 2.85 |
| 360.85 | 2.53 | 2.53 |
| 388.90 | 3.31 | 3.31 |
| 365.48 | 3.57 | 3.57 |
| 368.48 | 2.90 | 2.90 |
| 337.42 | 2.93 | 2.93 |
| 411.42 | 3.63 | 3.63 |
| 341.45 | 3.91 | 3.91 |
| 343.43 | 2.70 | 2.70 |
| 313.40 | 2.69 | 2.69 |
| 354.45 | 2.96 | 2.96 |
| 410.44 | 3.66 | 3.66 |
| 337.42 | 2.93 | 2.93 |
| 359.86 | 3.44 | 3.44 |
| 296.33 | 1.13 | 1.13 |
| 368.48 | 2.90 | 2.90 |
| 386.47 | 2.85 | 2.85 |
| 297.36 | 2.15 | 2.15 |
| 325.41 | 2.79 | 2.79 |
| 297.36 | 2.15 | 2.15 |
| 312.37 | 1.48 | 1.48 |
| 311.35 | 0.46 | 0.46 |
| 353.47 | 3.57 | 3.57 |
| 382.51 | 3.29 | 3.29 |
| 367.49 | 3.96 | 3.96 |
| 386.45 | 3.50 | 3.50 |
| 325.41 | 2.79 | 2.79 |
| 355.48 | 3.81 | 3.81 |
| 388.90 | 3.16 | 3.16 |
| 416.95 | 3.94 | 3.94 |
| 343.43 | 2.70 | 2.70 |
| 392.45 | 3.37 | 3.37 |
| 388.46 | 3.79 | 3.79 |
| 368.46 | 3.20 | 3.20 |
| 312.41 | 3.29 | 3.29 |