Basic Information
ID: ALA5265418
Type: Functional
Description: Anti-inflammatory activity against mast cell degranulation inflammatory C57BL/6J mouse model assessed as blood EC50 required for reduction in compound 48/80-induced PGD2 release into peritoneal lavage fluid administered orally with compound and 1 hr later treated with compound 48/80 and measured after 7 mins by LC-MS/MS analysis
Organism: Mus musculus
Strain: C57BL/6J
Cell type: Mast cell
Activity Charts
Bioactivity
Activity Types for Assay ALA5265418
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 378.42 | 3.90 | 3.90 |
| 353.47 | 3.57 | 3.57 |