Basic Information
ID: ALA5291725
Type: Binding
Description: Binding affinity towards human ADORA1 (agonistic activity) in an in vitro assay with cellular components measured by scintillation counting
Activity Charts
Bioactivity
Activity Types for Assay ALA5291725
AC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.41 | 1.78 | 1.78 |
| 331.35 | 1.58 | 1.58 |
| 430.38 | 2.88 | 2.88 |
| 172.21 | -0.08 | -0.08 |
| 389.39 | 0.97 | 0.97 |
| 357.35 | 3.56 | 3.56 |
| 853.92 | 3.74 | 3.74 |
| 305.50 | 3.20 | 3.20 |
| 331.35 | 1.58 | 1.58 |
| 749.00 | 1.90 | 1.90 |
| 325.43 | 1.41 | 1.41 |
| 733.94 | 1.79 | 1.79 |
| 300.44 | 5.60 | 5.60 |
| 426.49 | 4.83 | 4.83 |
| 324.40 | 3.81 | 3.81 |
| 144.21 | 2.29 | 2.29 |
| 260.25 | 1.11 | 1.11 |
| 369.43 | 2.74 | 2.74 |
| 471.69 | 6.45 | 6.45 |
| 474.57 | 1.84 | 1.84 |
| 387.44 | 1.06 | 1.06 |
| 454.91 | 3.96 | 3.96 |
| 481.51 | 4.63 | 4.63 |
| 412.56 | 5.80 | 5.80 |
| 169.22 | 0.64 | 0.64 |
| 284.43 | 4.24 | 4.24 |
| 151.25 | 1.91 | 1.91 |
| 146.21 | 0.26 | 0.26 |
| 159.23 | 1.75 | 1.75 |
| 182.17 | -3.59 | -3.59 |
| 296.41 | 3.61 | 3.61 |
| 264.37 | 2.62 | 2.62 |
| 300.44 | 5.60 | 5.60 |
| 412.95 | 3.81 | 3.81 |
| 277.28 | -0.83 | -0.83 |
| 331.87 | 4.88 | 4.88 |
| 386.53 | 4.66 | 4.66 |
| 308.38 | 0.53 | 0.53 |
| 358.46 | 1.43 | 1.43 |
| 350.40 | -1.89 | -1.89 |
| 354.49 | 3.04 | 3.04 |
| 174.20 | 1.80 | 1.80 |
| 530.46 | 5.19 | 5.19 |
| 477.05 | 5.09 | 5.09 |
| 149.21 | 0.15 | 0.15 |
| 292.24 | -2.07 | -2.07 |
| 545.63 | 2.58 | 2.58 |
| 249.10 | -1.27 | -1.27 |
| 810.99 | 3.99 | 3.99 |
| 223.27 | 1.11 | 1.11 |
| 495.64 | 5.27 | 5.27 |
| 463.50 | 5.91 | 5.91 |
| 435.89 | 2.55 | 2.55 |
| 480.65 | 4.94 | 4.94 |
| 269.39 | 3.66 | 3.66 |
| 315.87 | 5.19 | 5.19 |
| 440.61 | 2.95 | 2.95 |
| 404.34 | 5.50 | 5.50 |
| 361.40 | 4.11 | 4.11 |
| 229.63 | -1.08 | -1.08 |
| 149.28 | 1.54 | 1.54 |
| 248.33 | 1.69 | 1.69 |
| 343.88 | 4.13 | 4.13 |
| 514.59 | -1.04 | -1.04 |
| 224.22 | -0.71 | -0.71 |
| 197.19 | 0.05 | 0.05 |
| 435.29 | 4.72 | 4.72 |
| 520.48 | -1.13 | -1.13 |
| 411.47 | 3.42 | 3.42 |
| 398.35 | ||
| 184.15 | 2.91 | 2.91 |
| 301.39 | 2.81 | 2.81 |
| 393.36 | 1.99 | 1.99 |
| 415.50 | -0.32 | -0.32 |
| 445.55 | 2.08 | 2.08 |
| 334.17 | 2.89 | 2.89 |
| 166.24 | 1.98 | 1.98 |
| 379.44 | 3.68 | 3.68 |
| 448.39 | 4.86 | 4.86 |
| 812.02 | 4.93 | 4.93 |
| 163.17 | -2.97 | -2.97 |
| 404.93 | 4.75 | 4.75 |
| 367.88 | 2.09 | 2.09 |
| 359.45 | 2.99 | 2.99 |
| 405.50 | 1.24 | 1.24 |
| 212.25 | 3.04 | 3.04 |
| 213.24 | 2.66 | 2.66 |
| 416.95 | 4.61 | 4.61 |
| 392.50 | 3.41 | 3.41 |
| 461.47 | 2.64 | 2.64 |
| 317.22 | 2.45 | 2.45 |
| 276.29 | 1.21 | 1.21 |
| 361.39 | 4.42 | 4.42 |
| 265.36 | 2.69 | 2.69 |
| 191.14 | -1.28 | -1.28 |
| 280.32 | 4.25 | 4.25 |
| 109.13 | 0.25 | 0.25 |
| 416.47 | 3.09 | 3.09 |
| 475.52 | 0.94 | 0.94 |
| 363.50 | 3.31 | 3.31 |
| 447.54 | 2.97 | 2.97 |
| 325.50 | 5.34 | 5.34 |
| 435.89 | 2.52 | 2.52 |
| 700.79 | 4.57 | 4.57 |
| 86.14 | -0.82 | -0.82 |
| 137.16 | 0.32 | 0.32 |
| 519.69 | 1.71 | 1.71 |
| 534.49 | 4.97 | 4.97 |
| 225.21 | -1.33 | -1.33 |
| 339.37 | -0.40 | -0.40 |
| 1084.25 | ||
| 1069.24 | ||
| 435.90 | 4.39 | 4.39 |
| 130.08 | -0.80 | -0.80 |
| 555.52 | 7.13 | 7.13 |
| 236.30 | 0.81 | 0.81 |
| 384.44 | 0.55 | 0.55 |
| 1007.21 | ||
| 518.09 | 5.14 | 5.14 |
| 490.63 | 3.07 | 3.07 |
| 317.34 | 3.38 | 3.38 |
| 365.50 | 4.01 | 4.01 |
| 76.05 | -0.94 | -0.94 |
| 346.34 | 2.18 | 2.18 |
| 342.30 | -5.40 | -5.40 |
| 269.31 | 0.38 | 0.38 |
| 114.17 | 0.71 | 0.71 |
| 430.55 | 2.77 | 2.77 |
| 488.61 | 2.07 | 2.07 |
| 284.25 | 3.24 | 3.24 |
| 324.46 | 4.05 | 4.05 |
| 310.48 | 4.87 | 4.87 |
| 396.66 | 7.64 | 7.64 |
| 475.63 | 5.54 | 5.54 |
| 318.35 | 2.01 | 2.01 |
| 392.58 | 4.48 | 4.48 |
| 469.39 | 1.69 | 1.69 |
| 1255.44 | ||
| 926.11 | 0.94 | 0.94 |
| 421.31 | 4.71 | 4.71 |
| 811.88 | 3.16 | 3.16 |
| 317.39 | 2.28 | 2.28 |
| 228.25 | 2.63 | 2.63 |
| 343.90 | 5.10 | 5.10 |
| 473.57 | 1.10 | 1.10 |
| 363.39 | 0.15 | 0.15 |
| 402.49 | 2.56 | 2.56 |
| 877.04 | 5.65 | 5.65 |
| 863.36 | 17.85 | 17.85 |
| 538.58 | 4.93 | 4.93 |
| 182.17 | -3.59 | -3.59 |
| 747.96 | 2.44 | 2.44 |
| 452.55 | 2.61 | 2.61 |
| 398.42 | 1.39 | 1.39 |
| 446.64 | 3.18 | 3.18 |
| 898.05 | 3.91 | 3.91 |
| 320.40 | 2.59 | 2.59 |
| 510.48 | -0.17 | -0.17 |
| 464.44 | 3.99 | 3.99 |
| 305.37 | 2.37 | 2.37 |
| 242.23 | 2.62 | 2.62 |
| 330.36 | 2.12 | 2.12 |
| 1431.06 | ||
| 734.05 | 10.61 | 10.61 |
| 405.43 | -0.01 | -0.01 |
| 557.61 | 0.83 | 0.83 |
| 398.34 | 2.46 | 2.46 |
| 519.57 | -0.71 | -0.71 |
| 182.22 | -0.25 | -0.25 |
| 471.55 | -0.73 | -0.73 |
| 1269.43 | ||
| 388.46 | 2.58 | 2.58 |
| 502.75 | 8.24 | 8.24 |
| 190.16 | -1.03 | -1.03 |
| 288.18 | 2.86 | 2.86 |
| 310.44 | 3.66 | 3.66 |
| 488.33 | -2.23 | -2.23 |
| 835.09 | 2.20 | 2.20 |
| 184.28 | 3.38 | 3.38 |
| 248.16 | 2.33 | 2.33 |
| 379.89 | 1.60 | 1.60 |
| 320.39 | 3.95 | 3.95 |
| 190.16 | 1.85 | 1.85 |
| 370.49 | 4.19 | 4.19 |
| 288.35 | 3.93 | 3.93 |
| 387.23 | 1.78 | 1.78 |
| 206.31 | 2.50 | 2.50 |
| 556.66 | 1.32 | 1.32 |
| 314.41 | 1.46 | 1.46 |
| 476.54 | -1.04 | -1.04 |
| 482.82 | 5.69 | 5.69 |
| 583.60 | -7.95 | -7.95 |
| 234.29 | 2.84 | 2.84 |
| 546.94 | 4.51 | 4.51 |
| 649.67 | 6.58 | 6.58 |
| 286.28 | 3.00 | 3.00 |
| 382.89 | 1.18 | 1.18 |
| 284.36 | -2.67 | -2.67 |
| 272.35 | 2.86 | 2.86 |
| 300.49 | 5.26 | 5.26 |
| 440.77 | 1.92 | 1.92 |
| 371.43 | 1.10 | 1.10 |
| 470.54 | 2.67 | 2.67 |
| 354.19 | 3.58 | 3.58 |
| 548.46 | 1.85 | 1.85 |
| 591.56 | 8.52 | 8.52 |
| 404.55 | 3.43 | 3.43 |
| 349.47 | 2.64 | 2.64 |
| 790.00 | 2.75 | 2.75 |
| 411.47 | 4.63 | 4.63 |
| 2296.97 | ||
| 627.64 | 1.55 | 1.55 |
| 507.62 | 3.77 | 3.77 |
| 416.87 | 4.48 | 4.48 |
| 563.67 | 6.12 | 6.12 |
| 463.56 | 1.32 | 1.32 |
| 480.53 | 0.66 | 0.66 |
| 552.72 | 2.70 | 2.70 |
| 521.56 | 1.44 | 1.44 |
| 443.31 | 3.39 | 3.39 |
| 465.52 | 3.31 | 3.31 |
| 198.23 | -0.37 | -0.37 |
| 417.82 | 5.23 | 5.23 |
| 473.38 | 4.29 | 4.29 |
| 511.58 | 0.84 | 0.84 |
| 1620.69 |