Assay Report Card

Basic Information

ID: ALA5291732

Type: Binding

Description: Binding affinity towards human ADRA1A in an in vitro assay with cellular components (NIBR assay) measured by scintillation proximity assay

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
383.411.781.78
357.793.933.93
331.351.581.58
319.341.271.27
135.211.581.58
264.373.083.08
280.423.883.88
365.842.082.08
303.291.771.77
441.554.374.37
430.382.882.88
284.753.153.15
267.371.611.61
268.364.834.83
167.302.422.42
252.271.771.77
914.196.186.18
804.034.644.64
314.864.534.53
305.160.290.29
236.28-1.42-1.42
222.25-0.86-0.86
290.321.261.26
454.615.095.09
398.403.703.70
414.533.373.37
180.161.311.31
407.514.954.95
259.352.582.58
266.341.381.38
334.400.860.86
252.350.600.60
375.401.981.98
401.442.372.37
211.261.131.13
297.75-0.35-0.35
330.751.891.89
248.722.522.52
255.321.531.53
264.311.171.17
250.280.860.86
309.334.444.44
253.281.371.37
326.833.723.72
263.383.833.83
278.341.481.48
226.281.181.18
226.281.181.18
198.220.500.50
299.762.952.95
315.723.043.04
267.311.671.67
280.310.870.87
224.260.960.96
214.250.090.09
303.143.613.61
250.343.573.57
232.281.861.86
385.512.092.09
302.241.991.99
395.432.422.42
211.220.440.44
276.381.961.96
267.332.852.85
375.874.434.43
354.495.655.65
266.302.652.65
444.49-0.14-0.14
395.483.223.22
341.430.560.56
137.14-0.31-0.31
258.230.090.09
255.272.292.29
272.371.091.09
494.013.643.64
441.581.981.98
182.190.070.07
370.595.895.89
369.373.523.52
299.371.501.50
318.874.894.89
319.884.814.81
329.373.333.33
358.854.184.18
234.342.582.58
473.596.086.08
371.526.006.00
654.613.193.19
410.493.593.59
299.802.002.00
853.923.743.74
354.493.483.48
243.312.532.53
276.751.741.74
248.331.911.91
924.090.710.71
416.136.456.45
807.893.263.26
236.302.732.73
379.504.364.36
404.554.204.20
274.803.823.82
440.954.634.63
187.201.021.02
339.483.363.36
264.322.472.47
206.283.073.07
313.292.552.55
281.272.382.38
270.723.133.13
331.351.581.58
308.383.793.79
749.001.901.90
314.504.274.27
733.941.791.79
314.474.724.72
309.434.014.01
398.483.333.33
344.855.385.38
265.351.991.99
306.280.740.74
507.18-1.63-1.63
324.403.813.81
208.261.161.16
354.452.652.65
144.212.292.29
776.874.564.56
463.805.945.94
352.772.812.81
244.263.683.68
284.434.244.24
242.703.063.06
194.19-1.03-1.03
403.983.943.94
356.424.374.37
297.144.414.41
236.311.771.77
254.293.113.11
238.160.070.07
281.313.043.04
123.110.780.78
165.191.451.45
376.451.601.60
321.163.103.10
316.162.632.63
310.405.195.19
670.863.093.09
505.642.402.40
253.270.830.83
381.383.513.51
260.382.852.85
172.182.012.01
471.696.456.45
356.453.163.16
259.142.762.76
281.362.842.84
351.411.951.95
575.695.705.70
314.362.562.56
241.680.820.82
247.342.212.21
516.869.919.91
387.441.061.06
209.321.311.31
123.11-0.42-0.42
383.47-0.31-0.31
371.872.362.36
287.363.383.38
470.023.553.55
287.414.994.99
188.231.481.48
278.310.190.19
277.414.174.17
295.411.321.32
645.326.946.94
358.431.771.77
267.24-0.20-0.20
235.331.341.34
336.432.372.37
284.434.244.24
360.451.561.56
325.452.372.37
343.224.234.23
374.481.801.80
325.774.324.32
371.282.682.68
272.393.613.61
255.363.353.35
151.251.911.91
308.773.583.58
146.210.260.26
171.160.090.09
263.384.304.30
275.404.554.55
360.844.684.68
244.292.672.67
295.302.972.97
281.234.154.15
296.154.364.36
241.293.753.75
261.373.923.92
329.495.435.43
296.413.613.61
143.140.370.37
141.170.450.45
203.241.331.33
264.372.622.62
249.301.461.46
213.661.861.86
451.481.721.72
387.480.720.72
298.392.202.20
412.953.813.81
389.461.351.35
372.553.813.81
222.242.852.85
252.272.862.86
229.26-0.59-0.59
239.311.311.31
312.443.443.44
383.522.862.86
290.453.963.96
500.632.592.59
406.483.743.74
437.534.314.31
334.783.293.29
310.784.634.63
373.954.584.58
628.814.334.33
256.102.012.01
212.230.620.62
256.091.931.93
295.381.531.53
608.694.174.17
389.412.212.21
284.752.612.61
270.351.781.78
505.464.184.18
303.362.062.06
294.753.273.27
189.211.161.16
454.450.270.27
369.473.463.46
291.381.221.22
209.25-0.13-0.13
230.263.043.04
378.324.454.45
243.22-2.56-2.56
276.213.213.21
179.312.692.69
381.695.805.80
306.245.185.18
158.16-1.94-1.94
194.15-2.08-2.08
424.524.744.74
312.422.322.32
318.343.203.20
157.22-0.21-0.21
311.411.771.77
320.320.660.66
361.833.553.55
327.813.773.77
404.493.803.80
263.793.963.96
235.07-1.66-1.66
180.251.151.15
424.502.572.57
292.381.701.70
295.73-0.06-0.06
416.655.705.70
279.341.811.81
295.454.374.37
211.22-0.50-0.50
278.403.923.92
458.585.355.35
218.260.540.54
244.320.800.80
292.24-2.07-2.07
246.101.551.55
475.585.315.31
368.525.115.11
314.372.962.96
204.31-0.29-0.29
588.561.341.34
1449.27
249.10-1.27-1.27
1202.63
157.210.840.84
365.842.712.71
321.340.540.54
277.193.003.00
247.25-0.46-0.46
171.241.901.90
263.20-1.29-1.29
239.753.303.30
480.654.944.94
271.403.383.38
374.913.063.06
285.372.202.20
250.203.043.04
337.46-0.77-0.77
543.530.000.00
269.351.911.91
400.984.244.24
307.403.253.25
501.675.515.51
178.190.420.42
404.345.505.50
283.11-0.37-0.37
301.392.962.96
395.42-0.17-0.17
504.64-0.02-0.02
226.282.642.64
171.241.371.37
211.331.581.58
229.63-1.08-1.08
290.413.713.71
305.423.793.79
260.313.173.17
551.634.204.20
179.312.552.55
270.213.253.25
151.211.071.07
147.20-0.21-0.21
300.752.472.47
387.894.004.00
187.292.182.18
282.223.543.54
705.655.585.58
312.412.532.53
218.250.980.98
198.220.430.43
286.465.515.51
317.485.775.77
224.22-0.71-0.71
319.230.500.50
382.894.894.89
388.903.153.15
300.753.373.37
354.454.614.61
337.381.641.64
366.554.834.83
197.190.050.05
237.301.451.45
244.383.153.15
610.676.326.32
440.464.034.03
514.637.267.26
266.344.604.60
261.091.881.88
200.283.183.18
301.392.812.81
307.392.572.57
248.311.681.68
131.180.590.59
290.271.551.55
307.424.954.95
338.770.920.92
159.231.081.08
418.574.594.59
287.362.352.35
353.471.941.94
345.442.582.58
352.484.364.36
268.741.401.40
228.293.373.37
293.324.034.03
287.453.943.94
364.423.043.04
445.552.082.08
231.263.253.25
253.721.721.72
129.160.360.36
365.410.020.02
302.373.573.57
343.473.493.49
238.240.960.96
298.302.752.75
354.193.913.91
143.231.691.69
217.271.771.77
225.160.970.97
351.843.333.33
294.362.412.41
334.422.302.30
448.394.864.86
313.793.433.43
180.17-1.04-1.04
296.20-0.80-0.80
326.445.175.17
424.532.442.44
327.343.053.05
348.432.532.53
299.413.433.43
384.25
298.433.493.49
704.874.214.21
429.564.044.04
332.35-2.93-2.93
416.522.382.38
344.504.844.84
310.834.024.02
297.424.634.63
176.180.600.60
270.341.231.23
604.703.543.54
397.484.344.34
443.643.473.47
284.454.254.25
262.220.840.84
167.210.650.65
359.452.992.99
247.280.530.53
397.766.526.52
388.821.571.57
260.332.022.02
405.501.241.24
188.221.891.89
255.372.652.65
374.914.044.04
416.954.614.61
392.503.413.41
415.574.114.11
266.340.450.45
317.222.452.45
240.312.822.82
378.113.193.19
380.471.351.35
324.423.173.17
531.444.214.21
265.362.692.69
82.110.720.72
191.14-1.28-1.28
273.724.164.16
221.301.051.05
273.242.552.55
767.911.521.52
280.324.254.25
464.835.555.55
199.321.561.56
205.260.240.24
426.563.963.96
324.34-0.80-0.80
557.055.935.93
416.473.093.09
510.835.455.45
929.168.078.07
572.886.116.11
344.412.222.22
430.542.722.72
251.712.902.90
169.571.771.77
273.362.012.01
260.313.173.17
413.432.882.88
325.505.345.34
484.50-7.29-7.29
416.584.854.85
585.61-8.42-8.42
581.58-8.16-8.16
427.552.312.31
323.421.631.63
165.241.331.33
279.864.744.74
488.023.313.31
461.565.865.86
288.433.883.88
425.923.353.35
230.681.681.68
822.954.344.34
418.452.972.97
392.471.901.90
225.21-1.33-1.33
339.37-0.40-0.40
129.17-1.03-1.03
444.44-0.35-0.35
480.57-1.28-1.28
169.180.090.09
332.31-3.58-3.58
585.660.510.51
555.527.137.13
444.44-0.21-0.21
166.251.281.28
362.471.781.78
424.095.465.46
315.684.074.07
336.453.333.33
406.55-0.86-0.86
366.845.515.51
202.641.071.07
211.221.621.62
180.17-1.04-1.04
204.302.152.15
210.280.070.07
299.371.931.93
369.491.291.29
236.23-0.21-0.21
129.09-0.51-0.51
308.333.613.61
353.333.523.52
336.302.902.90
679.862.452.45
136.110.060.06
164.202.092.09
534.434.954.95
500.584.434.43
228.253.463.46
318.301.741.74
337.464.224.22
384.263.963.96
419.534.914.91
496.633.903.90
161.220.180.18
265.343.243.24
198.18-1.03-1.03
422.924.274.27
474.591.611.61
558.656.316.31
244.21-3.17-3.17
408.882.272.27
611.746.486.48
344.462.732.73
338.443.463.46
476.593.643.64
346.342.182.18
383.382.882.88
428.544.784.78
442.42-0.44-0.44
170.241.381.38
305.342.642.64
302.282.522.52
248.311.961.96
391.296.116.11
349.525.405.40
284.253.243.24
289.740.880.88
335.883.783.78
277.271.151.15
650.983.953.95
318.352.012.01
391.565.975.97
408.881.841.84
469.391.691.69
217.290.630.63
645.61-8.56-8.56
315.412.972.97
300.403.593.59
789.10-0.03-0.03
149.241.971.97
167.211.421.42
360.372.572.57
410.584.984.98
324.402.212.21
165.241.331.33
464.860.260.26
438.522.572.57
257.260.810.81
423.470.480.48
542.58-0.92-0.92
421.314.714.71
470.463.633.63
309.410.630.63
785.896.166.16
390.965.565.56
343.905.105.10
434.472.352.35
244.21-3.01-3.01
371.392.582.58
435.481.271.27
250.301.641.64
267.28-4.49-4.49
351.474.434.43
634.734.574.57
320.055.935.93
538.584.934.93
432.563.133.13
421.421.631.63
186.241.561.56
385.382.462.46
388.423.203.20
347.400.440.44
465.953.363.36
583.692.082.08
813.983.623.62
303.360.920.92
303.68-0.35-0.35
780.952.222.22
424.990.390.39
138.06-0.09-0.09
192.261.591.59
331.300.010.01
321.833.673.67
398.421.391.39
450.355.045.04
371.823.183.18
414.503.123.12
257.25-1.76-1.76
1139.76
532.574.464.46
323.372.982.98
477.564.264.26
205.302.602.60
341.430.280.28
404.423.073.07
296.414.034.03
488.583.703.70
387.725.865.86
821.14-1.63-1.63
578.664.164.16
414.595.295.29
376.472.922.92
284.362.212.21
370.534.504.50
412.615.095.09
558.604.174.17
273.741.621.62
502.583.523.52
380.875.875.87
224.260.960.96
428.615.975.97
329.443.473.47
528.546.586.58
398.342.462.46
431.952.242.24
451.623.193.19
416.512.332.33
241.240.530.53
228.21-2.14-2.14
310.443.923.92
364.535.235.23
231.251.421.42
344.503.943.94
307.444.424.42
612.650.330.33
177.251.741.74
340.494.834.83
254.29-0.19-0.19
239.311.911.91
289.423.923.92
353.534.114.11
404.512.422.42
183.682.622.62
319.253.933.93
314.261.741.74
1322.50
289.813.533.53
354.37-1.44-1.44
167.210.770.77
111.15-0.09-0.09
291.392.182.18
278.424.364.36
357.322.712.71
339.441.921.92
380.461.871.87
421.474.524.52
322.504.394.39
339.484.284.28
263.382.632.63
527.570.470.47
185.232.152.15
429.605.415.41
524.694.824.82
386.484.644.64
289.371.931.93
603.752.832.83
177.462.132.13
255.792.832.83
276.383.483.48
295.454.684.68
434.502.472.47
371.832.302.30
457.693.533.53
279.383.963.96
365.483.343.34
431.562.662.66
314.411.461.46
259.393.553.55
392.505.085.08
540.704.704.70
1346.38
385.492.982.98
602.64-0.45-0.45
326.441.551.55
283.312.752.75
386.493.303.30
345.874.524.52
1227.40
505.574.214.21
395.572.142.14
411.474.634.63
398.687.727.72
331.471.321.32
203.282.922.92
540.023.913.91
1526.77
490.442.352.35
239.363.753.75
740.761.541.54