Assay Report Card

Basic Information

ID: ALA5291736

Type: Binding

Description: Binding affinity towards human ADRA2A in an in vitro assay with cellular components measured by scintillation counting

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
383.411.781.78
162.241.851.85
361.371.541.54
232.241.421.42
357.793.933.93
233.24-0.79-0.79
300.30-1.52-1.52
331.351.581.58
270.374.794.79
236.14-1.06-1.06
264.373.083.08
441.554.374.37
430.382.882.88
249.352.152.15
268.364.834.83
914.196.186.18
314.864.534.53
216.192.552.55
258.321.341.34
543.530.000.00
236.28-1.42-1.42
186.24-0.21-0.21
172.21-0.08-0.08
231.091.811.81
454.615.095.09
180.161.311.31
341.430.560.56
302.242.912.91
259.352.582.58
252.350.600.60
328.412.142.14
389.390.970.97
466.632.392.39
330.751.891.89
357.353.563.56
300.445.605.60
326.833.723.72
399.975.975.97
331.183.753.75
250.343.573.57
232.281.861.86
395.432.422.42
375.874.434.43
340.432.882.88
194.190.080.08
282.476.116.11
153.180.600.60
76.05-0.96-0.96
414.412.412.41
258.230.090.09
441.581.981.98
351.411.561.56
654.613.193.19
410.493.593.59
468.372.112.11
853.923.743.74
406.916.616.61
305.503.203.20
261.091.881.88
160.180.920.92
111.15-0.09-0.09
137.180.890.89
275.351.771.77
133.10-1.13-1.13
198.272.702.70
379.504.364.36
105.09-1.61-1.61
309.413.423.42
259.352.782.78
244.890.430.43
296.154.744.74
176.171.811.81
285.392.662.66
214.051.161.16
233.702.252.25
304.223.383.38
287.414.704.70
206.283.073.07
211.261.081.08
331.351.581.58
749.001.901.90
325.431.411.41
733.941.791.79
314.474.724.72
122.121.381.38
137.140.970.97
94.111.391.39
334.33-1.65-1.65
300.445.605.60
426.494.834.83
223.301.941.94
324.403.813.81
393.443.413.41
354.452.652.65
144.212.292.29
365.792.362.36
260.251.111.11
244.263.683.68
151.161.351.35
166.181.571.57
179.222.042.04
297.144.414.41
352.435.265.26
380.420.950.95
118.09-0.06-0.06
359.402.282.28
613.802.872.87
567.804.754.75
253.270.830.83
369.432.742.74
305.762.732.73
471.696.456.45
456.572.722.72
356.453.163.16
89.09-0.58-0.58
502.800.420.42
341.411.531.53
314.362.562.56
403.534.064.06
474.571.841.84
387.441.061.06
454.913.963.96
123.11-0.42-0.42
200.17-0.02-0.02
350.400.700.70
131.13-1.10-1.10
194.19-0.18-0.18
287.363.383.38
292.434.154.15
481.514.634.63
201.252.692.69
412.565.805.80
281.423.223.22
169.220.640.64
340.494.484.48
356.493.663.66
277.414.174.17
392.471.901.90
267.24-0.20-0.20
349.322.182.18
323.130.910.91
284.434.244.24
294.444.124.12
300.833.683.68
266.393.023.02
414.353.443.44
272.393.613.61
255.363.353.35
287.361.851.85
151.251.911.91
126.00-0.16-0.16
146.210.260.26
398.471.761.76
159.231.751.75
1297.30
214.652.582.58
199.300.700.70
296.154.364.36
241.293.753.75
182.17-3.59-3.59
216.192.552.55
296.413.613.61
94.120.660.66
92.09-1.67-1.67
264.372.622.62
213.661.861.86
290.400.270.27
153.140.670.67
300.445.605.60
495.543.073.07
451.481.721.72
351.454.994.99
412.953.813.81
372.553.813.81
277.28-0.83-0.83
229.26-0.59-0.59
383.522.862.86
331.874.884.88
386.534.664.66
108.141.181.18
230.312.612.61
295.452.852.85
167.200.600.60
628.814.334.33
75.07-0.49-0.49
150.222.822.82
404.505.395.39
237.732.902.90
261.231.451.45
234.202.782.78
371.352.482.48
308.380.530.53
210.282.382.38
333.14-0.46-0.46
76.10-0.64-0.64
198.310.740.74
358.461.431.43
350.40-1.89-1.89
102.09-1.62-1.62
608.694.174.17
75.07-0.97-0.97
211.261.131.13
393.35-2.68-2.68
356.065.865.86
206.332.792.79
226.322.932.93
299.504.584.58
354.10-1.22-1.22
303.362.062.06
190.21-0.96-0.96
230.263.043.04
276.213.213.21
238.25-1.19-1.19
319.253.933.93
354.493.043.04
401.441.901.90
287.300.640.64
320.320.660.66
326.474.444.44
298.454.494.49
194.242.972.97
327.813.773.77
231.301.551.55
174.201.801.80
424.502.572.57
530.465.195.19
477.055.095.09
273.25-0.33-0.33
259.260.030.03
149.210.150.15
392.412.082.08
305.211.931.93
375.492.592.59
458.585.355.35
292.24-2.07-2.07
201.222.562.56
121.16-0.67-0.67
284.486.336.33
368.525.115.11
226.232.232.23
314.372.962.96
260.242.862.86
570.933.743.74
545.632.582.58
198.140.190.19
249.10-1.27-1.27
206.03-0.99-0.99
810.993.993.99
223.271.111.11
495.645.275.27
463.505.915.91
162.14-0.31-0.31
342.30-5.40-5.40
435.892.552.55
470.333.203.20
480.654.944.94
269.393.663.66
335.341.481.48
543.530.000.00
315.875.195.19
501.675.515.51
440.612.952.95
246.19-1.68-1.68
104.17-0.32-0.32
404.345.505.50
181.190.350.35
165.190.640.64
115.13-0.18-0.18
132.16-0.86-0.86
132.12-1.73-1.73
308.312.762.76
309.454.194.19
720.965.915.91
209.252.552.55
171.241.371.37
361.404.114.11
229.63-1.08-1.08
119.12-1.22-1.22
389.891.231.23
310.340.880.88
149.281.541.54
421.903.093.09
296.553.623.62
407.994.464.46
462.542.202.20
160.240.640.64
226.240.120.12
198.220.430.43
318.763.813.81
221.302.492.49
248.331.691.69
262.352.212.21
343.884.134.13
514.59-1.04-1.04
452.492.372.37
224.22-0.71-0.71
388.903.153.15
270.382.922.92
197.190.050.05
435.294.724.72
346.11
304.546.466.46
237.301.451.45
349.770.710.71
520.48-1.13-1.13
411.473.423.42
514.637.267.26
254.293.113.11
257.292.192.19
398.35
348.496.106.10
184.152.912.91
375.565.045.04
301.392.812.81
384.442.122.12
207.230.310.31
393.361.991.99
384.657.627.62
296.392.322.32
472.759.069.06
427.555.295.29
145.161.941.94
380.660.820.82
247.140.520.52
415.50-0.32-0.32
179.221.201.20
190.151.491.49
418.574.594.59
321.381.811.81
352.484.364.36
233.353.163.16
396.953.153.15
445.552.082.08
262.362.992.99
296.333.063.06
334.172.892.89
824.973.523.52
386.594.904.90
136.200.690.69
404.502.352.35
284.382.172.17
226.662.532.53
166.241.981.98
249.322.472.47
379.443.683.68
152.15-2.95-2.95
223.271.911.91
378.433.523.52
448.394.864.86
181.220.570.57
263.382.732.73
390.36-2.43-2.43
246.19-1.69-1.69
812.024.934.93
409.434.894.89
122.130.180.18
304.444.024.02
163.17-2.97-2.97
152.151.181.18
161.20-1.81-1.81
402.492.132.13
404.934.754.75
196.11
245.332.352.35
521.444.874.87
498.582.582.58
367.882.092.09
310.834.024.02
831.98-1.84-1.84
456.686.176.17
258.493.523.52
609.746.706.70
214.25-0.56-0.56
240.353.173.17
293.412.972.97
235.332.622.62
397.484.344.34
306.453.723.72
312.485.025.02
293.454.874.87
167.210.650.65
259.352.572.57
359.452.992.99
205.261.281.28
448.955.685.68
324.383.493.49
312.411.291.29
357.493.343.34
405.501.241.24
212.253.043.04
255.372.652.65
213.242.662.66
364.445.305.30
215.23-0.37-0.37
416.954.614.61
392.503.413.41
461.472.642.64
192.12-1.25-1.25
339.614.714.71
429.136.126.12
372.813.143.14
200.282.112.11
540.711.431.43
240.442.642.64
317.222.452.45
249.273.603.60
276.291.211.21
170.21-0.13-0.13
361.394.424.42
293.434.684.68
214.210.580.58
291.443.473.47
309.412.272.27
377.512.782.78
536.8912.6112.61
525.64-0.65-0.65
258.232.312.31
242.273.673.67
154.12-0.28-0.28
324.423.173.17
265.362.692.69
457.616.266.26
532.474.464.46
220.230.830.83
191.14-1.28-1.28
338.462.842.84
547.672.382.38
269.390.840.84
280.324.254.25
175.240.940.94
109.130.250.25
693.738.388.38
131.13-1.21-1.21
255.272.972.97
495.756.886.88
345.402.552.55
371.25
416.473.093.09
475.520.940.94
510.835.455.45
169.180.080.08
556.777.057.05
430.542.722.72
251.712.902.90
363.503.313.31
447.542.972.97
253.742.212.21
399.635.045.04
261.252.352.35
261.713.373.37
325.505.345.34
615.63-8.86-8.86
288.392.582.58
298.433.643.64
180.201.961.96
200.242.972.97
312.453.883.88
435.892.522.52
700.794.574.57
307.292.232.23
270.373.823.82
408.583.453.45
86.14-0.82-0.82
207.272.442.44
151.93
137.160.320.32
519.691.711.71
461.565.865.86
152.180.640.64
534.494.974.97
225.21-1.33-1.33
324.450.610.61
339.37-0.40-0.40
1084.25
1069.24
435.904.394.39
130.08-0.80-0.80
149.210.110.11
129.17-1.03-1.03
318.391.061.06
457.480.190.19
516.725.675.67
584.66-1.51-1.51
157.10-0.58-0.58
555.527.137.13
236.300.810.81
414.482.482.48
359.262.672.67
384.440.550.55
182.220.730.73
211.221.621.62
394.440.620.62
180.17-1.04-1.04
215.221.561.56
390.413.173.17
154.120.800.80
1007.21
608.55-1.09-1.09
1134.99
136.110.060.06
518.095.145.14
310.474.634.63
847.024.624.62
697.784.754.75
242.670.290.29
500.584.434.43
459.564.884.88
490.633.073.07
312.453.883.88
479.533.683.68
317.343.383.38
522.582.012.01
365.504.014.01
301.474.334.33
281.444.574.57
408.882.272.27
376.144.564.56
344.252.112.11
329.874.934.93
317.474.244.24
388.852.792.79
295.433.803.80
382.464.444.44
281.403.893.89
315.465.565.56
391.474.414.41
337.575.565.56
156.612.662.66
764.953.253.25
494.532.942.94
76.05-0.94-0.94
346.342.182.18
345.422.902.90
342.30-5.40-5.40
382.533.823.82
269.310.380.38
356.515.355.35
114.170.710.71
446.513.663.66
475.684.024.02
430.552.772.77
488.612.072.07
444.420.910.91
284.253.243.24
324.464.054.05
310.484.874.87
396.667.647.64
310.340.880.88
253.26-0.90-0.90
475.635.545.54
444.668.928.92
307.33-2.21-2.21
318.352.012.01
424.543.053.05
151.211.281.28
265.360.610.61
478.890.440.44
450.719.169.16
408.881.841.84
392.584.484.48
469.391.691.69
1255.44
176.12-1.41-1.41
926.110.940.94
289.381.931.93
156.272.442.44
207.23-3.26-3.26
404.82
353.515.225.22
302.465.995.99
221.21-3.08-3.08
468.593.313.31
645.61-8.56-8.56
354.812.562.56
656.662.752.75
284.381.411.41
311.360.770.77
475.59-3.20-3.20
360.240.600.60
392.471.751.75
368.471.941.94
371.30-1.74-1.74
358.273.263.26
438.522.572.57
268.27-2.71-2.71
175.19-1.15-1.15
421.314.714.71
811.883.163.16
985.130.610.61
943.090.040.04
317.392.282.28
340.442.702.70
390.965.565.56
228.252.632.63
343.905.105.10
179.17-3.25-3.25
473.571.101.10
363.390.150.15
492.595.635.63
402.492.562.56
196.16-3.49-3.49
260.22-1.57-1.57
877.045.655.65
317.524.664.66
1270.29
863.3617.8517.85
278.445.665.66
524.8711.5411.54
538.584.934.93
182.17-3.59-3.59
278.341.481.48
251.05
326.443.403.40
539.59-0.23-0.23
778.954.754.75
410.472.092.09
397.524.934.93
285.320.370.37
268.27-2.71-2.71
747.962.442.44
147.13-0.74-0.74
420.635.115.11
282.342.392.39
303.360.920.92
260.341.801.80
254.25-2.21-2.21
520.395.305.30
328.484.504.50
376.472.782.78
190.201.581.58
383.900.940.94
240.31-0.81-0.81
452.552.612.61
398.421.391.39
245.661.181.18
180.16-3.22-3.22
446.643.183.18
245.373.303.30
221.261.791.79
306.371.071.07
315.595.295.29
282.302.552.55
398.45-3.26-3.26
898.053.913.91
422.401.311.31
145.16-0.53-0.53
320.402.592.59
510.48-0.17-0.17
142.20-0.20-0.20
464.443.993.99
225.291.131.13
354.452.952.95
316.383.723.72
368.504.734.73
412.646.076.07
483.470.630.63
305.372.372.37
428.605.145.14
289.813.303.30
301.392.872.87
242.232.622.62
210.66
314.433.833.83
330.362.122.12
1431.06
521.054.094.09
494.532.992.99
214.053.253.25
384.524.434.43
810.475.725.72
1056.24
734.0510.6110.61
454.973.893.89
312.454.504.50
195.220.740.74
229.242.192.19
494.583.443.44
484.974.054.05
405.43-0.01-0.01
396.576.136.13
495.034.604.60
205.25-1.14-1.14
436.522.502.50
557.610.830.83
398.342.462.46
519.57-0.71-0.71
182.22-0.25-0.25
451.623.193.19
384.524.584.58
340.464.064.06
1030.30
513.685.955.95
471.55-0.73-0.73
437.787.027.02
1209.42
254.29-0.19-0.19
325.462.292.29
290.382.032.03
291.392.332.33
334.264.124.12
1269.43
388.462.582.58
340.443.953.95
140.19-1.02-1.02
307.432.392.39
348.513.483.48
319.253.933.93
1268.88
472.452.012.01
317.502.852.85
1311.47
256.332.612.61
309.485.025.02
502.758.248.24
318.534.724.72
410.461.841.84
388.904.174.17
411.595.385.38
373.453.893.89
190.16-1.03-1.03
288.182.862.86
310.443.663.66
180.16-3.83-3.83
488.33-2.23-2.23
356.230.400.40
492.694.264.26
835.092.202.20
476.870.220.22
283.413.643.64
298.351.021.02
514.53-0.14-0.14
529.461.661.66
184.283.383.38
429.605.415.41
519.59-1.84-1.84
426.864.074.07
493.54-1.36-1.36
275.350.360.36
244.252.342.34
211.220.140.14
142.180.740.74
248.162.332.33
416.512.372.37
484.393.913.91
379.891.601.60
455.383.743.74
294.310.710.71
159.192.252.25
234.261.301.30
261.392.712.71
225.20-1.63-1.63
308.342.132.13
340.384.084.08
438.483.573.57
292.773.733.73
295.392.982.98
219.630.700.70
320.393.953.95
190.161.851.85
313.293.113.11
426.593.373.37
250.261.871.87
370.494.194.19
365.347.007.00
165.191.181.18
288.353.933.93
234.280.200.20
314.864.074.07
296.393.423.42
403.442.892.89
280.310.870.87
263.363.523.52
395.505.425.42
300.362.062.06
444.902.412.41
387.231.781.78
182.181.401.40
271.091.271.27
360.472.232.23
481.531.651.65
383.534.454.45
245.332.622.62
332.462.852.85
367.453.583.58
276.383.683.68
206.312.502.50
279.383.963.96
1093.33
624.875.465.46
127.171.451.45
439.582.412.41
313.402.982.98
265.25-1.53-1.53
556.661.321.32
272.142.562.56
370.792.612.61
309.351.301.30
794.982.872.87
482.634.774.77
137.191.301.30
398.552.502.50
357.935.505.50
577.732.522.52
219.282.862.86
314.411.461.46
187.241.011.01
440.514.224.22
476.54-1.04-1.04
361.421.061.06
887.131.711.71
828.013.163.16
166.220.920.92
482.825.695.69
583.60-7.95-7.95
452.544.684.68
234.292.842.84
221.651.851.85
404.462.152.15
427.424.344.34
444.522.972.97
491.543.823.82
213.19-0.46-0.46
546.944.514.51
649.676.586.58
249.352.552.55
178.241.561.56
554.73-1.63-1.63
261.373.843.84
446.563.993.99
286.283.003.00
382.891.181.18
271.403.343.34
231.23-0.84-0.84
355.393.453.45
284.36-2.67-2.67
272.352.862.86
286.443.853.85
300.495.265.26
440.771.921.92
501.515.545.54
371.431.101.10
623.724.044.04
173.210.770.77
418.410.340.34
297.404.134.13
408.363.013.01
460.573.313.31
470.542.672.67
304.822.742.74
461.503.283.28
273.303.493.49
354.193.583.58
217.302.222.22
355.821.611.61
255.321.141.14
475.342.082.08
370.31-1.14-1.14
374.372.532.53
205.240.600.60
548.461.851.85
450.921.611.61
591.568.528.52
422.422.442.44
404.553.433.43
476.622.972.97
446.644.124.12
1239.45
145.251.271.27
408.882.272.27
1237.52
427.564.674.67
349.472.642.64
361.03
531.323.783.78
415.433.753.75
790.002.752.75
411.474.634.63
2296.97
170.251.471.47
352.352.862.86
627.641.551.55
392.18
405.976.566.56
507.623.773.77
418.583.563.56
324.382.522.52
889.028.618.61
416.874.484.48
1390.73
563.676.126.12
742.68-2.69-2.69
463.561.321.32
330.364.054.05
504.970.510.51
1040.24
365.41-0.07-0.07
480.530.660.66
552.722.702.70
478.594.504.50
521.561.441.44
443.313.393.39
584.115.095.09
461.500.830.83
280.52-0.65-0.65
465.523.313.31
198.23-0.37-0.37
486.605.105.10
417.825.235.23
530.182.092.09
266.39
473.384.294.29
582.974.324.32
342.484.004.00
483.502.982.98
332.421.451.45
530.515.755.75
439.585.305.30
511.580.840.84
757.953.903.90
604.72-0.04-0.04
434.534.604.60
1620.69
341.373.303.30
315.22-1.66-1.66