Basic Information
ID: ALA5291756
Type: Functional
Description: Compound was evaluated for inhibition of human CACNA1C in an in vitro cell-based assay measured by IonWorks automated patch clamp
Format: BAO_0000219
Target: Voltage-gated L-type calcium channel alpha-1C subunit(ALA1940)
Document: ALA5291721
Compound was evaluated for inhibition of human CACNA1C in an in vitro cell-based assay measured by IonWorks automated patch clamp: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5291756
AC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 280.42 | 3.88 | 3.88 |
| 252.27 | 1.77 | 1.77 |
| 914.19 | 6.18 | 6.18 |
| 804.03 | 4.64 | 4.64 |
| 414.53 | 3.37 | 3.37 |
| 259.35 | 2.58 | 2.58 |
| 326.83 | 3.72 | 3.72 |
| 444.49 | -0.14 | -0.14 |
| 272.37 | 1.09 | 1.09 |
| 441.58 | 1.98 | 1.98 |
| 318.87 | 4.89 | 4.89 |
| 266.39 | 3.53 | 3.53 |
| 410.49 | 3.59 | 3.59 |
| 440.95 | 4.63 | 4.63 |
| 339.48 | 3.36 | 3.36 |
| 733.94 | 1.79 | 1.79 |
| 384.59 | 4.16 | 4.16 |
| 399.44 | 2.87 | 2.87 |
| 179.26 | 2.03 | 2.03 |
| 471.69 | 6.45 | 6.45 |
| 337.35 | 1.12 | 1.12 |
| 281.42 | 3.22 | 3.22 |
| 277.41 | 4.17 | 4.17 |
| 341.45 | 3.24 | 3.24 |
| 645.32 | 6.94 | 6.94 |
| 323.13 | 0.91 | 0.91 |
| 414.35 | 3.44 | 3.44 |
| 255.36 | 3.35 | 3.35 |
| 171.16 | 0.09 | 0.09 |
| 355.87 | 5.18 | 5.18 |
| 329.49 | 5.43 | 5.43 |
| 264.37 | 2.62 | 2.62 |
| 412.95 | 3.81 | 3.81 |
| 229.26 | -0.59 | -0.59 |
| 383.52 | 2.86 | 2.86 |
| 234.20 | 2.78 | 2.78 |
| 284.75 | 2.61 | 2.61 |
| 369.47 | 3.46 | 3.46 |
| 306.24 | 5.18 | 5.18 |
| 318.34 | 3.20 | 3.20 |
| 392.41 | 2.08 | 2.08 |
| 458.58 | 5.35 | 5.35 |
| 475.58 | 5.31 | 5.31 |
| 495.64 | 5.27 | 5.27 |
| 543.53 | 0.00 | 0.00 |
| 501.67 | 5.51 | 5.51 |
| 554.59 | -1.20 | -1.20 |
| 382.89 | 4.89 | 4.89 |
| 366.55 | 4.83 | 4.83 |
| 304.54 | 6.46 | 6.46 |
| 262.36 | 2.99 | 2.99 |
| 343.47 | 3.49 | 3.49 |
| 379.44 | 3.68 | 3.68 |
| 297.42 | 4.63 | 4.63 |
| 303.41 | 1.17 | 1.17 |
| 324.42 | 3.17 | 3.17 |
| 272.39 | 3.26 | 3.26 |
| 281.44 | 4.99 | 4.99 |
| 403.21 | 5.03 | 5.03 |
| 427.55 | 2.31 | 2.31 |
| 407.32 | 2.02 | 2.02 |
| 461.56 | 5.86 | 5.86 |
| 425.92 | 3.35 | 3.35 |
| 418.45 | 2.97 | 2.97 |
| 211.22 | 1.62 | 1.62 |
| 496.63 | 3.90 | 3.90 |
| 479.53 | 3.68 | 3.68 |
| 408.88 | 2.27 | 2.27 |
| 611.74 | 6.48 | 6.48 |
| 346.34 | 2.18 | 2.18 |
| 444.42 | 0.91 | 0.91 |
| 529.53 | 6.36 | 6.36 |
| 391.56 | 5.97 | 5.97 |
| 404.82 | ||
| 360.37 | 2.57 | 2.57 |
| 295.85 | 4.17 | 4.17 |
| 421.31 | 4.71 | 4.71 |
| 343.90 | 5.10 | 5.10 |
| 244.21 | -3.01 | -3.01 |
| 371.39 | 2.58 | 2.58 |
| 492.59 | 5.63 | 5.63 |
| 465.95 | 3.36 | 3.36 |
| 420.63 | 5.11 | 5.11 |
| 450.35 | 5.04 | 5.04 |
| 464.44 | 3.99 | 3.99 |
| 424.62 | 5.12 | 5.12 |
| 382.54 | 4.26 | 4.26 |
| 238.20 | 0.70 | 0.70 |
| 349.39 | 4.44 | 4.44 |
| 489.93 | 5.54 | 5.54 |
| 356.23 | 0.40 | 0.40 |
| 529.46 | 1.66 | 1.66 |
| 738.89 | 6.22 | 6.22 |
| 308.12 | 4.50 | 4.50 |
| 326.44 | 1.55 | 1.55 |
| 505.57 | 4.21 | 4.21 |
| 441.23 | 3.01 | 3.01 |
| 540.02 | 3.91 | 3.91 |
| 582.97 | 4.32 | 4.32 |
| 483.50 | 2.98 | 2.98 |