Assay Report Card

Basic Information

ID: ALA5291765

Type: Functional

Description: Antagonist activity at human CHRM2 in an in vitro cell-based assay measured by fluorescent imaging plate reader

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
383.411.781.78
357.793.933.93
369.341.701.70
331.351.581.58
319.341.271.27
135.211.581.58
264.373.083.08
280.423.883.88
365.842.082.08
303.291.771.77
441.554.374.37
430.382.882.88
284.753.153.15
267.371.611.61
249.352.152.15
268.364.834.83
167.302.422.42
252.271.771.77
914.196.186.18
804.034.644.64
314.864.534.53
305.160.290.29
236.28-1.42-1.42
222.25-0.86-0.86
290.321.261.26
454.615.095.09
398.403.703.70
414.533.373.37
266.340.450.45
180.161.311.31
407.514.954.95
259.352.582.58
266.341.381.38
334.400.860.86
416.361.891.89
252.350.600.60
375.401.981.98
401.442.372.37
211.261.131.13
297.75-0.35-0.35
330.751.891.89
248.722.522.52
255.321.531.53
264.311.171.17
250.280.860.86
581.671.991.99
309.334.444.44
253.281.371.37
326.833.723.72
263.383.833.83
278.341.481.48
226.281.181.18
226.281.181.18
212.250.790.79
198.220.500.50
299.762.952.95
315.723.043.04
267.311.671.67
280.310.870.87
224.260.960.96
214.250.090.09
393.474.514.51
303.143.613.61
250.343.573.57
232.281.861.86
385.512.092.09
302.241.991.99
395.432.422.42
211.220.440.44
276.381.961.96
267.332.852.85
375.874.434.43
354.495.655.65
266.302.652.65
278.445.665.66
444.49-0.14-0.14
341.430.560.56
223.282.682.68
137.14-0.31-0.31
258.230.090.09
255.272.292.29
272.371.091.09
494.013.643.64
441.581.981.98
243.394.334.33
182.190.070.07
267.25-1.98-1.98
370.595.895.89
369.373.523.52
287.22-0.05-0.05
299.371.501.50
318.874.894.89
266.393.533.53
232.281.351.35
319.884.814.81
329.373.333.33
358.854.184.18
234.342.582.58
351.411.561.56
276.423.753.75
473.596.086.08
371.526.006.00
654.613.193.19
347.382.652.65
410.493.593.59
299.802.002.00
853.923.743.74
354.493.483.48
243.312.532.53
276.751.741.74
316.430.500.50
248.331.911.91
924.090.710.71
416.136.456.45
807.893.263.26
236.302.732.73
275.351.771.77
379.504.364.36
404.554.204.20
228.252.032.03
274.803.823.82
259.352.782.78
440.954.634.63
187.201.021.02
339.483.363.36
264.322.472.47
333.361.611.61
206.283.073.07
313.292.552.55
281.272.382.38
270.723.133.13
178.273.643.64
331.351.581.58
383.41-0.56-0.56
308.383.793.79
278.363.953.95
749.001.901.90
314.504.274.27
733.941.791.79
384.594.164.16
314.474.724.72
426.564.134.13
309.434.014.01
398.483.333.33
344.855.385.38
265.351.991.99
306.280.740.74
426.494.834.83
352.473.253.25
313.403.193.19
507.18-1.63-1.63
324.403.813.81
399.442.872.87
393.443.413.41
354.452.652.65
144.212.292.29
404.352.042.04
260.251.111.11
179.262.032.03
776.874.564.56
463.805.945.94
238.332.852.85
351.351.801.80
352.772.812.81
244.263.683.68
284.434.244.24
242.703.063.06
151.161.351.35
254.283.403.40
194.19-1.03-1.03
403.983.943.94
286.722.452.45
356.424.374.37
297.144.414.41
236.311.771.77
254.293.113.11
238.160.070.07
281.313.043.04
123.110.780.78
165.191.451.45
348.401.131.13
376.451.601.60
321.163.103.10
316.162.632.63
310.405.195.19
670.863.093.09
505.642.402.40
253.270.830.83
381.383.513.51
395.462.552.55
260.382.852.85
172.182.012.01
471.696.456.45
257.383.083.08
356.453.163.16
357.442.492.49
259.142.762.76
281.362.842.84
207.231.311.31
351.411.951.95
163.20-0.49-0.49
131.13-0.62-0.62
575.695.705.70
314.362.562.56
241.680.820.82
339.393.863.86
382.543.953.95
247.342.212.21
516.869.919.91
246.312.792.79
146.24-1.92-1.92
291.732.852.85
387.441.061.06
209.321.311.31
123.11-0.42-0.42
230.313.303.30
396.450.590.59
407.585.685.68
387.913.783.78
354.471.701.70
337.351.121.12
383.47-0.31-0.31
371.872.362.36
287.363.383.38
470.023.553.55
281.423.223.22
287.414.994.99
188.231.481.48
278.310.190.19
277.414.174.17
295.411.321.32
341.453.243.24
645.326.946.94
358.431.771.77
277.413.043.04
267.24-0.20-0.20
381.914.304.30
235.331.341.34
255.363.723.72
336.432.372.37
284.434.244.24
360.451.561.56
325.452.372.37
343.224.234.23
405.442.362.36
374.481.801.80
414.353.443.44
230.102.362.36
265.362.482.48
325.774.324.32
371.282.682.68
315.371.051.05
272.393.613.61
255.363.353.35
151.251.911.91
308.773.583.58
277.414.214.21
171.160.090.09
263.384.304.30
275.404.554.55
189.220.160.16
360.844.684.68
159.231.751.75
183.210.350.35
367.810.620.62
244.292.672.67
355.875.185.18
295.302.972.97
281.234.154.15
296.154.364.36
241.293.753.75
261.373.923.92
329.495.435.43
296.413.613.61
218.100.860.86
143.140.370.37
141.170.450.45
203.241.331.33
334.383.103.10
264.372.622.62
136.200.840.84
324.383.663.66
249.301.461.46
213.661.861.86
451.481.721.72
387.480.720.72
475.364.434.43
298.392.202.20
412.953.813.81
389.461.351.35
372.553.813.81
222.242.852.85
252.272.862.86
229.26-0.59-0.59
239.311.311.31
312.443.443.44
383.522.862.86
331.874.884.88
270.763.633.63
290.453.963.96
420.324.534.53
500.632.592.59
379.502.892.89
406.483.743.74
437.534.314.31
334.783.293.29
310.784.634.63
373.954.584.58
628.814.334.33
211.180.020.02
429.564.604.60
256.102.012.01
234.202.782.78
468.544.904.90
212.230.620.62
308.380.530.53
347.22-1.86-1.86
303.834.194.19
256.091.931.93
260.382.852.85
295.381.531.53
160.221.231.23
299.35-0.18-0.18
608.694.174.17
199.16-1.10-1.10
389.412.212.21
327.473.373.37
284.752.612.61
270.351.781.78
586.208.958.95
612.633.633.63
505.464.184.18
303.362.062.06
294.753.273.27
189.211.161.16
454.450.270.27
369.473.463.46
291.381.221.22
518.066.096.09
209.25-0.13-0.13
230.263.043.04
378.324.454.45
243.22-2.56-2.56
276.213.213.21
179.312.692.69
381.695.805.80
219.241.461.46
306.245.185.18
142.16-0.91-0.91
158.16-1.94-1.94
194.15-2.08-2.08
319.253.933.93
317.233.843.84
424.524.744.74
312.422.322.32
318.343.203.20
157.22-0.21-0.21
311.411.771.77
246.31-0.28-0.28
320.320.660.66
361.833.553.55
182.17-0.23-0.23
327.813.773.77
404.493.803.80
621.934.634.63
263.793.963.96
235.07-1.66-1.66
180.251.151.15
408.522.342.34
435.44-1.17-1.17
546.59-1.30-1.30
424.502.572.57
292.381.701.70
295.73-0.06-0.06
220.281.371.37
292.141.761.76
416.655.705.70
279.341.811.81
289.555.145.14
295.454.374.37
381.453.773.77
211.22-0.50-0.50
278.403.923.92
458.585.355.35
470.616.336.33
218.260.540.54
244.320.800.80
292.24-2.07-2.07
218.261.471.47
246.101.551.55
475.585.315.31
290.793.403.40
368.525.115.11
314.372.962.96
204.31-0.29-0.29
588.561.341.34
1449.27
249.10-1.27-1.27
363.411.701.70
348.442.122.12
1202.63
157.210.840.84
365.842.712.71
321.340.540.54
277.193.003.00
247.25-0.46-0.46
471.522.992.99
171.241.901.90
263.20-1.29-1.29
239.753.303.30
480.654.944.94
271.403.383.38
374.913.063.06
285.372.202.20
250.203.043.04
337.46-0.77-0.77
484.645.105.10
543.530.000.00
269.351.911.91
214.272.192.19
400.984.244.24
307.403.253.25
501.675.515.51
178.190.420.42
404.345.505.50
501.482.702.70
554.59-1.20-1.20
283.11-0.37-0.37
301.392.962.96
410.511.521.52
395.42-0.17-0.17
308.312.762.76
504.64-0.02-0.02
226.282.642.64
720.965.915.91
446.914.284.28
171.241.371.37
284.362.952.95
211.331.581.58
319.412.922.92
229.63-1.08-1.08
290.413.713.71
305.423.793.79
260.313.173.17
551.634.204.20
179.312.552.55
270.213.253.25
151.211.071.07
300.752.472.47
387.894.004.00
352.744.094.09
187.292.182.18
270.213.003.00
282.223.543.54
705.655.585.58
312.412.532.53
218.250.980.98
198.220.430.43
339.442.512.51
248.331.691.69
343.884.134.13
325.453.773.77
286.465.515.51
514.59-1.04-1.04
317.485.775.77
535.525.425.42
224.22-0.71-0.71
427.460.100.10
319.230.500.50
382.894.894.89
469.677.227.22
388.903.153.15
300.753.373.37
354.454.614.61
139.150.400.40
337.381.641.64
322.484.634.63
214.23-0.25-0.25
366.554.834.83
197.190.050.05
237.301.451.45
244.383.153.15
610.676.326.32
440.464.034.03
514.637.267.26
266.344.604.60
340.472.932.93
261.091.881.88
200.283.183.18
301.392.812.81
384.442.122.12
434.472.252.25
339.39-0.24-0.24
219.28-1.45-1.45
356.513.623.62
307.392.572.57
248.311.681.68
131.180.590.59
290.271.551.55
432.604.194.19
328.431.171.17
307.424.954.95
338.770.920.92
415.50-0.32-0.32
159.231.081.08
418.574.594.59
287.362.352.35
353.471.941.94
345.442.582.58
352.484.364.36
268.741.401.40
228.293.373.37
293.324.034.03
287.453.943.94
364.423.043.04
445.552.082.08
418.975.785.78
231.263.253.25
427.534.114.11
253.721.721.72
129.160.360.36
365.410.020.02
302.373.573.57
411.573.493.49
343.473.493.49
246.352.732.73
238.240.960.96
204.231.301.30
298.302.752.75
354.193.913.91
289.362.032.03
143.231.691.69
179.220.720.72
491.635.755.75
288.443.903.90
311.473.963.96
290.370.260.26
217.271.771.77
225.160.970.97
351.843.333.33
212.252.982.98
500.438.648.64
432.503.413.41
294.362.412.41
334.422.302.30
448.394.864.86
313.793.433.43
180.17-1.04-1.04
118.16-0.22-0.22
405.450.880.88
309.494.404.40
296.20-0.80-0.80
326.445.175.17
337.464.504.50
291.444.714.71
424.532.442.44
327.343.053.05
462.51-0.23-0.23
348.432.532.53
373.883.333.33
299.413.433.43
384.25
298.433.493.49
704.874.214.21
429.564.044.04
332.35-2.93-2.93
416.522.382.38
153.140.670.67
344.504.844.84
367.882.092.09
310.834.024.02
297.424.634.63
176.180.600.60
317.433.243.24
287.361.921.92
261.714.094.09
270.341.231.23
220.322.322.32
294.392.562.56
339.420.700.70
604.703.543.54
397.484.344.34
308.422.952.95
443.643.473.47
284.454.254.25
193.252.232.23
262.220.840.84
302.413.973.97
378.410.490.49
301.734.344.34
167.210.650.65
359.452.992.99
247.280.530.53
397.766.526.52
388.821.571.57
348.454.024.02
192.262.512.51
256.102.012.01
260.332.022.02
405.501.241.24
188.221.891.89
255.372.652.65
213.242.662.66
374.914.044.04
303.411.171.17
390.390.450.45
392.503.413.41
461.472.642.64
415.574.114.11
266.340.450.45
412.536.686.68
372.813.143.14
452.605.225.22
317.222.452.45
240.312.822.82
170.21-0.13-0.13
378.113.193.19
346.855.045.04
380.471.351.35
473.417.497.49
380.494.474.47
324.423.173.17
411.796.646.64
531.444.214.21
363.803.293.29
315.484.274.27
362.412.422.42
265.362.692.69
679.78-2.40-2.40
82.110.720.72
290.362.042.04
191.14-1.28-1.28
163.20-0.49-0.49
273.724.164.16
279.382.982.98
221.301.051.05
273.242.552.55
272.393.263.26
767.911.521.52
280.324.254.25
464.835.555.55
433.353.723.72
205.260.240.24
426.563.963.96
324.34-0.80-0.80
240.374.214.21
195.692.592.59
416.473.093.09
606.788.688.68
349.410.320.32
510.835.455.45
929.168.078.07
572.886.116.11
344.412.222.22
405.460.330.33
281.444.994.99
430.542.722.72
415.833.473.47
251.712.902.90
169.571.771.77
373.462.072.07
363.503.313.31
384.432.602.60
307.392.772.77
273.362.012.01
260.313.173.17
206.283.073.07
360.382.312.31
314.475.855.85
413.432.882.88
399.635.045.04
387.483.743.74
403.215.035.03
286.341.091.09
325.505.345.34
484.50-7.29-7.29
416.584.854.85
302.464.274.27
435.892.522.52
211.271.801.80
994.21-3.04-3.04
585.61-8.42-8.42
303.361.871.87
581.58-8.16-8.16
293.372.932.93
527.643.523.52
427.552.312.31
266.341.121.12
323.421.631.63
165.241.331.33
207.272.442.44
563.630.750.75
279.864.744.74
315.421.161.16
488.023.313.31
407.322.022.02
461.565.865.86
288.433.883.88
425.923.353.35
230.681.681.68
822.954.344.34
418.452.972.97
392.471.901.90
255.23-1.97-1.97
225.21-1.33-1.33
339.37-0.40-0.40
129.17-1.03-1.03
444.44-0.35-0.35
454.52-0.64-0.64
424.39-0.54-0.54
453.882.692.69
480.57-1.28-1.28
602.687.337.33
169.180.090.09
332.31-3.58-3.58
585.660.510.51
555.527.137.13
444.44-0.21-0.21
166.251.281.28
458.501.981.98
828.013.013.01
362.471.781.78
424.095.465.46
315.684.074.07
336.453.333.33
406.55-0.86-0.86
327.123.863.86
366.845.515.51
135.13-0.11-0.11
202.641.071.07
211.221.621.62
180.17-1.04-1.04
204.302.152.15
210.280.070.07
433.502.522.52
299.371.931.93
369.491.291.29
237.732.902.90
236.23-0.21-0.21
129.09-0.51-0.51
308.333.613.61
353.333.523.52
336.302.902.90
136.110.060.06
459.512.702.70
179.20-0.78-0.78
164.202.092.09
534.434.954.95
500.584.434.43
753.942.732.73
228.253.463.46
392.584.484.48
318.301.741.74
337.464.224.22
384.263.963.96
419.534.914.91
496.633.903.90
265.343.243.24
198.18-1.03-1.03
422.924.274.27
474.591.611.61
558.656.316.31
244.21-3.17-3.17
408.882.272.27
351.374.084.08
304.322.982.98
611.746.486.48
344.462.732.73
338.443.463.46
481.552.402.40
476.593.643.64
212.250.940.94
346.342.182.18
383.382.882.88
342.30-5.40-5.40
434.502.422.42
335.472.202.20
324.403.813.81
366.504.314.31
434.502.272.27
428.544.784.78
442.42-0.44-0.44
170.241.381.38
530.663.013.01
305.342.642.64
302.282.522.52
248.311.961.96
391.296.116.11
349.525.405.40
293.734.164.16
284.253.243.24
529.536.366.36
246.351.771.77
289.740.880.88
310.484.874.87
339.353.653.65
335.883.783.78
387.53-1.31-1.31
461.500.090.09
453.46-0.54-0.54
277.271.151.15
650.983.953.95
391.565.975.97
392.584.484.48
469.391.691.69
217.290.630.63
645.61-8.56-8.56
492.534.284.28
594.67-0.59-0.59
315.412.972.97
366.482.172.17
300.403.593.59
789.10-0.03-0.03
149.241.971.97
167.211.421.42
455.554.404.40
360.372.572.57
268.27-1.18-1.18
417.511.601.60
465.531.301.30
410.584.984.98
324.402.212.21
165.241.331.33
464.860.260.26
438.522.572.57
220.313.463.46
570.776.836.83
295.854.174.17
257.260.810.81
423.470.480.48
542.58-0.92-0.92
349.410.350.35
410.43-0.05-0.05
253.353.243.24
575.63-1.40-1.40
460.512.432.43
421.314.714.71
470.463.633.63
420.51-1.60-1.60
309.410.630.63
785.896.166.16
285.69-0.30-0.30
441.40-0.04-0.04
390.965.565.56
776.874.564.56
228.252.632.63
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