Basic Information
ID: ALA5291776
Type: Binding
Description: Binding affinity towards human CRHR2 in an in vitro assay with cellular components measured by scintillation proximity assay
Activity Charts
Bioactivity
Activity Types for Assay ALA5291776
AC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.41 | 1.78 | 1.78 |
| 357.79 | 3.93 | 3.93 |
| 331.35 | 1.58 | 1.58 |
| 135.21 | 1.58 | 1.58 |
| 264.37 | 3.08 | 3.08 |
| 280.42 | 3.88 | 3.88 |
| 441.55 | 4.37 | 4.37 |
| 430.38 | 2.88 | 2.88 |
| 284.75 | 3.15 | 3.15 |
| 267.37 | 1.61 | 1.61 |
| 268.36 | 4.83 | 4.83 |
| 252.27 | 1.77 | 1.77 |
| 914.19 | 6.18 | 6.18 |
| 804.03 | 4.64 | 4.64 |
| 290.32 | 1.26 | 1.26 |
| 454.61 | 5.09 | 5.09 |
| 398.40 | 3.70 | 3.70 |
| 414.53 | 3.37 | 3.37 |
| 180.16 | 1.31 | 1.31 |
| 407.51 | 4.95 | 4.95 |
| 259.35 | 2.58 | 2.58 |
| 252.35 | 0.60 | 0.60 |
| 211.26 | 1.13 | 1.13 |
| 297.75 | -0.35 | -0.35 |
| 330.75 | 1.89 | 1.89 |
| 255.32 | 1.53 | 1.53 |
| 309.33 | 4.44 | 4.44 |
| 253.28 | 1.37 | 1.37 |
| 326.83 | 3.72 | 3.72 |
| 315.72 | 3.04 | 3.04 |
| 280.31 | 0.87 | 0.87 |
| 250.34 | 3.57 | 3.57 |
| 232.28 | 1.86 | 1.86 |
| 302.24 | 1.99 | 1.99 |
| 267.33 | 2.85 | 2.85 |
| 375.87 | 4.43 | 4.43 |
| 266.30 | 2.65 | 2.65 |
| 444.49 | -0.14 | -0.14 |
| 137.14 | -0.31 | -0.31 |
| 258.23 | 0.09 | 0.09 |
| 441.58 | 1.98 | 1.98 |
| 370.59 | 5.89 | 5.89 |
| 369.37 | 3.52 | 3.52 |
| 299.37 | 1.50 | 1.50 |
| 318.87 | 4.89 | 4.89 |
| 329.37 | 3.33 | 3.33 |
| 358.85 | 4.18 | 4.18 |
| 234.34 | 2.58 | 2.58 |
| 473.59 | 6.08 | 6.08 |
| 371.52 | 6.00 | 6.00 |
| 654.61 | 3.19 | 3.19 |
| 410.49 | 3.59 | 3.59 |
| 299.80 | 2.00 | 2.00 |
| 853.92 | 3.74 | 3.74 |
| 243.31 | 2.53 | 2.53 |
| 276.75 | 1.74 | 1.74 |
| 379.50 | 4.36 | 4.36 |
| 404.55 | 4.20 | 4.20 |
| 274.80 | 3.82 | 3.82 |
| 339.48 | 3.36 | 3.36 |
| 206.28 | 3.07 | 3.07 |
| 313.29 | 2.55 | 2.55 |
| 270.72 | 3.13 | 3.13 |
| 749.00 | 1.90 | 1.90 |
| 314.50 | 4.27 | 4.27 |
| 344.85 | 5.38 | 5.38 |
| 306.28 | 0.74 | 0.74 |
| 324.40 | 3.81 | 3.81 |
| 354.45 | 2.65 | 2.65 |
| 144.21 | 2.29 | 2.29 |
| 776.87 | 4.56 | 4.56 |
| 463.80 | 5.94 | 5.94 |
| 284.43 | 4.24 | 4.24 |
| 242.70 | 3.06 | 3.06 |
| 194.19 | -1.03 | -1.03 |
| 286.72 | 2.45 | 2.45 |
| 356.42 | 4.37 | 4.37 |
| 297.14 | 4.41 | 4.41 |
| 123.11 | 0.78 | 0.78 |
| 376.45 | 1.60 | 1.60 |
| 321.16 | 3.10 | 3.10 |
| 670.86 | 3.09 | 3.09 |
| 253.27 | 0.83 | 0.83 |
| 381.38 | 3.51 | 3.51 |
| 260.38 | 2.85 | 2.85 |
| 471.69 | 6.45 | 6.45 |
| 356.45 | 3.16 | 3.16 |
| 357.44 | 2.49 | 2.49 |
| 281.36 | 2.84 | 2.84 |
| 351.41 | 1.95 | 1.95 |
| 314.36 | 2.56 | 2.56 |
| 516.86 | 9.91 | 9.91 |
| 387.44 | 1.06 | 1.06 |
| 123.11 | -0.42 | -0.42 |
| 371.87 | 2.36 | 2.36 |
| 470.02 | 3.55 | 3.55 |
| 277.41 | 4.17 | 4.17 |
| 295.41 | 1.32 | 1.32 |
| 358.43 | 1.77 | 1.77 |
| 267.24 | -0.20 | -0.20 |
| 284.43 | 4.24 | 4.24 |
| 360.45 | 1.56 | 1.56 |
| 325.45 | 2.37 | 2.37 |
| 230.10 | 2.36 | 2.36 |
| 371.28 | 2.68 | 2.68 |
| 272.39 | 3.61 | 3.61 |
| 255.36 | 3.35 | 3.35 |
| 308.77 | 3.58 | 3.58 |
| 146.21 | 0.26 | 0.26 |
| 275.40 | 4.55 | 4.55 |
| 360.84 | 4.68 | 4.68 |
| 281.23 | 4.15 | 4.15 |
| 296.15 | 4.36 | 4.36 |
| 296.41 | 3.61 | 3.61 |
| 264.37 | 2.62 | 2.62 |
| 213.66 | 1.86 | 1.86 |
| 451.48 | 1.72 | 1.72 |
| 298.39 | 2.20 | 2.20 |
| 412.95 | 3.81 | 3.81 |
| 372.55 | 3.81 | 3.81 |
| 229.26 | -0.59 | -0.59 |
| 312.44 | 3.44 | 3.44 |
| 383.52 | 2.86 | 2.86 |
| 406.48 | 3.74 | 3.74 |
| 437.53 | 4.31 | 4.31 |
| 373.95 | 4.58 | 4.58 |
| 628.81 | 4.33 | 4.33 |
| 256.10 | 2.01 | 2.01 |
| 284.75 | 2.61 | 2.61 |
| 270.35 | 1.78 | 1.78 |
| 303.36 | 2.06 | 2.06 |
| 454.45 | 0.27 | 0.27 |
| 291.38 | 1.22 | 1.22 |
| 230.26 | 3.04 | 3.04 |
| 179.31 | 2.69 | 2.69 |
| 306.24 | 5.18 | 5.18 |
| 194.15 | -2.08 | -2.08 |
| 424.52 | 4.74 | 4.74 |
| 312.42 | 2.32 | 2.32 |
| 157.22 | -0.21 | -0.21 |
| 320.32 | 0.66 | 0.66 |
| 327.81 | 3.77 | 3.77 |
| 263.79 | 3.96 | 3.96 |
| 235.07 | -1.66 | -1.66 |
| 424.50 | 2.57 | 2.57 |
| 530.46 | 5.19 | 5.19 |
| 458.58 | 5.35 | 5.35 |
| 314.37 | 2.96 | 2.96 |
| 204.31 | -0.29 | -0.29 |
| 249.10 | -1.27 | -1.27 |
| 1202.63 | ||
| 321.34 | 0.54 | 0.54 |
| 239.75 | 3.30 | 3.30 |
| 271.40 | 3.38 | 3.38 |
| 374.91 | 3.06 | 3.06 |
| 337.46 | -0.77 | -0.77 |
| 269.35 | 1.91 | 1.91 |
| 307.40 | 3.25 | 3.25 |
| 501.67 | 5.51 | 5.51 |
| 283.11 | -0.37 | -0.37 |
| 301.39 | 2.96 | 2.96 |
| 720.96 | 5.91 | 5.91 |
| 171.24 | 1.37 | 1.37 |
| 229.63 | -1.08 | -1.08 |
| 551.63 | 4.20 | 4.20 |
| 270.21 | 3.25 | 3.25 |
| 151.21 | 1.07 | 1.07 |
| 300.75 | 2.47 | 2.47 |
| 705.65 | 5.58 | 5.58 |
| 198.22 | 0.43 | 0.43 |
| 224.22 | -0.71 | -0.71 |
| 319.23 | 0.50 | 0.50 |
| 382.89 | 4.89 | 4.89 |
| 388.90 | 3.15 | 3.15 |
| 366.55 | 4.83 | 4.83 |
| 197.19 | 0.05 | 0.05 |
| 237.30 | 1.45 | 1.45 |
| 610.67 | 6.32 | 6.32 |
| 440.46 | 4.03 | 4.03 |
| 514.63 | 7.26 | 7.26 |
| 301.39 | 2.81 | 2.81 |
| 290.27 | 1.55 | 1.55 |
| 159.23 | 1.08 | 1.08 |
| 418.57 | 4.59 | 4.59 |
| 353.47 | 1.94 | 1.94 |
| 352.48 | 4.36 | 4.36 |
| 293.32 | 4.03 | 4.03 |
| 364.42 | 3.04 | 3.04 |
| 445.55 | 2.08 | 2.08 |
| 231.26 | 3.25 | 3.25 |
| 253.72 | 1.72 | 1.72 |
| 365.41 | 0.02 | 0.02 |
| 334.42 | 2.30 | 2.30 |
| 448.39 | 4.86 | 4.86 |
| 313.79 | 3.43 | 3.43 |
| 299.41 | 3.43 | 3.43 |
| 416.52 | 2.38 | 2.38 |
| 310.83 | 4.02 | 4.02 |
| 397.48 | 4.34 | 4.34 |
| 443.64 | 3.47 | 3.47 |
| 284.45 | 4.25 | 4.25 |
| 167.21 | 0.65 | 0.65 |
| 359.45 | 2.99 | 2.99 |
| 388.82 | 1.57 | 1.57 |
| 260.33 | 2.02 | 2.02 |
| 405.50 | 1.24 | 1.24 |
| 266.34 | 0.45 | 0.45 |
| 378.11 | 3.19 | 3.19 |
| 265.36 | 2.69 | 2.69 |
| 191.14 | -1.28 | -1.28 |
| 205.26 | 0.24 | 0.24 |
| 324.34 | -0.80 | -0.80 |
| 251.71 | 2.90 | 2.90 |
| 273.36 | 2.01 | 2.01 |
| 413.43 | 2.88 | 2.88 |
| 325.50 | 5.34 | 5.34 |
| 416.58 | 4.85 | 4.85 |
| 581.58 | -8.16 | -8.16 |
| 165.24 | 1.33 | 1.33 |
| 279.86 | 4.74 | 4.74 |
| 461.56 | 5.86 | 5.86 |
| 822.95 | 4.34 | 4.34 |
| 534.49 | 4.97 | 4.97 |
| 225.21 | -1.33 | -1.33 |
| 339.37 | -0.40 | -0.40 |
| 435.90 | 4.39 | 4.39 |
| 129.17 | -1.03 | -1.03 |
| 444.44 | -0.35 | -0.35 |
| 362.47 | 1.78 | 1.78 |
| 339.40 | 0.39 | 0.39 |
| 180.17 | -1.04 | -1.04 |
| 299.37 | 1.93 | 1.93 |
| 308.33 | 3.61 | 3.61 |
| 136.11 | 0.06 | 0.06 |
| 164.20 | 2.09 | 2.09 |
| 500.58 | 4.43 | 4.43 |
| 384.26 | 3.96 | 3.96 |
| 422.92 | 4.27 | 4.27 |
| 474.59 | 1.61 | 1.61 |
| 558.65 | 6.31 | 6.31 |
| 408.88 | 2.27 | 2.27 |
| 338.44 | 3.46 | 3.46 |
| 346.34 | 2.18 | 2.18 |
| 383.38 | 2.88 | 2.88 |
| 428.54 | 4.78 | 4.78 |
| 277.27 | 1.15 | 1.15 |
| 650.98 | 3.95 | 3.95 |
| 469.39 | 1.69 | 1.69 |
| 645.61 | -8.56 | -8.56 |
| 149.24 | 1.97 | 1.97 |
| 360.37 | 2.57 | 2.57 |
| 408.92 | 2.17 | 2.17 |
| 165.24 | 1.33 | 1.33 |
| 438.52 | 2.57 | 2.57 |
| 390.96 | 5.56 | 5.56 |
| 347.40 | 0.44 | 0.44 |
| 465.95 | 3.36 | 3.36 |
| 583.69 | 2.08 | 2.08 |
| 564.57 | 4.67 | 4.67 |
| 424.99 | 0.39 | 0.39 |
| 192.26 | 1.59 | 1.59 |
| 321.83 | 3.67 | 3.67 |
| 398.42 | 1.39 | 1.39 |
| 371.82 | 3.18 | 3.18 |
| 414.50 | 3.12 | 3.12 |
| 257.25 | -1.76 | -1.76 |
| 205.30 | 2.60 | 2.60 |
| 296.41 | 4.03 | 4.03 |
| 521.05 | 4.09 | 4.09 |
| 558.60 | 4.17 | 4.17 |
| 177.25 | 1.74 | 1.74 |
| 254.29 | -0.19 | -0.19 |
| 289.42 | 3.92 | 3.92 |
| 183.68 | 2.62 | 2.62 |
| 380.46 | 1.87 | 1.87 |
| 339.48 | 4.28 | 4.28 |
| 263.38 | 2.63 | 2.63 |
| 1058.05 | ||
| 434.50 | 2.47 | 2.47 |
| 279.38 | 3.96 | 3.96 |
| 314.41 | 1.46 | 1.46 |
| 485.51 | 5.82 | 5.82 |
| 411.47 | 4.63 | 4.63 |
| 490.44 | 2.35 | 2.35 |