Basic Information
ID: ALA5291799
Type: Binding
Description: Binding affinity towards human GABRA1 in an in vitro assay with cellular components measured by scintillation counting
Activity Charts
Bioactivity
Activity Types for Assay ALA5291799
AC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 162.24 | 1.85 | 1.85 |
| 361.37 | 1.54 | 1.54 |
| 232.24 | 1.42 | 1.42 |
| 300.30 | -1.52 | -1.52 |
| 236.14 | -1.06 | -1.06 |
| 264.37 | 3.08 | 3.08 |
| 441.55 | 4.37 | 4.37 |
| 249.35 | 2.15 | 2.15 |
| 268.36 | 4.83 | 4.83 |
| 314.86 | 4.53 | 4.53 |
| 216.19 | 2.55 | 2.55 |
| 258.32 | 1.34 | 1.34 |
| 236.28 | -1.42 | -1.42 |
| 231.09 | 1.81 | 1.81 |
| 454.61 | 5.09 | 5.09 |
| 180.16 | 1.31 | 1.31 |
| 341.43 | 0.56 | 0.56 |
| 259.35 | 2.58 | 2.58 |
| 328.41 | 2.14 | 2.14 |
| 466.63 | 2.39 | 2.39 |
| 330.75 | 1.89 | 1.89 |
| 300.44 | 5.60 | 5.60 |
| 326.83 | 3.72 | 3.72 |
| 399.97 | 5.97 | 5.97 |
| 331.18 | 3.75 | 3.75 |
| 232.28 | 1.86 | 1.86 |
| 395.43 | 2.42 | 2.42 |
| 375.87 | 4.43 | 4.43 |
| 340.43 | 2.88 | 2.88 |
| 194.19 | 0.08 | 0.08 |
| 282.47 | 6.11 | 6.11 |
| 153.18 | 0.60 | 0.60 |
| 76.05 | -0.96 | -0.96 |
| 414.41 | 2.41 | 2.41 |
| 441.58 | 1.98 | 1.98 |
| 351.41 | 1.56 | 1.56 |
| 410.49 | 3.59 | 3.59 |
| 468.37 | 2.11 | 2.11 |
| 406.91 | 6.61 | 6.61 |
| 261.09 | 1.88 | 1.88 |
| 160.18 | 0.92 | 0.92 |
| 111.15 | -0.09 | -0.09 |
| 275.35 | 1.77 | 1.77 |
| 198.27 | 2.70 | 2.70 |
| 379.50 | 4.36 | 4.36 |
| 309.41 | 3.42 | 3.42 |
| 259.35 | 2.78 | 2.78 |
| 296.15 | 4.74 | 4.74 |
| 304.22 | 3.38 | 3.38 |
| 287.41 | 4.70 | 4.70 |
| 206.28 | 3.07 | 3.07 |
| 211.26 | 1.08 | 1.08 |
| 314.47 | 4.72 | 4.72 |
| 122.12 | 1.38 | 1.38 |
| 94.11 | 1.39 | 1.39 |
| 223.30 | 1.94 | 1.94 |
| 393.44 | 3.41 | 3.41 |
| 354.45 | 2.65 | 2.65 |
| 365.79 | 2.36 | 2.36 |
| 151.16 | 1.35 | 1.35 |
| 166.18 | 1.57 | 1.57 |
| 352.43 | 5.26 | 5.26 |
| 380.42 | 0.95 | 0.95 |
| 118.09 | -0.06 | -0.06 |
| 359.40 | 2.28 | 2.28 |
| 613.80 | 2.87 | 2.87 |
| 567.80 | 4.75 | 4.75 |
| 253.27 | 0.83 | 0.83 |
| 305.76 | 2.73 | 2.73 |
| 471.69 | 6.45 | 6.45 |
| 456.57 | 2.72 | 2.72 |
| 502.80 | 0.42 | 0.42 |
| 341.41 | 1.53 | 1.53 |
| 314.36 | 2.56 | 2.56 |
| 123.11 | -0.42 | -0.42 |
| 350.40 | 0.70 | 0.70 |
| 131.13 | -1.10 | -1.10 |
| 194.19 | -0.18 | -0.18 |
| 287.36 | 3.38 | 3.38 |
| 201.25 | 2.69 | 2.69 |
| 281.42 | 3.22 | 3.22 |
| 340.49 | 4.48 | 4.48 |
| 277.41 | 4.17 | 4.17 |
| 392.47 | 1.90 | 1.90 |
| 349.32 | 2.18 | 2.18 |
| 294.44 | 4.12 | 4.12 |
| 300.83 | 3.68 | 3.68 |
| 266.39 | 3.02 | 3.02 |
| 272.39 | 3.61 | 3.61 |
| 255.36 | 3.35 | 3.35 |
| 287.36 | 1.85 | 1.85 |
| 1297.30 | ||
| 199.30 | 0.70 | 0.70 |
| 296.15 | 4.36 | 4.36 |
| 182.17 | -3.59 | -3.59 |
| 216.19 | 2.55 | 2.55 |
| 92.09 | -1.67 | -1.67 |
| 213.66 | 1.86 | 1.86 |
| 290.40 | 0.27 | 0.27 |
| 153.14 | 0.67 | 0.67 |
| 495.54 | 3.07 | 3.07 |
| 451.48 | 1.72 | 1.72 |
| 412.95 | 3.81 | 3.81 |
| 383.52 | 2.86 | 2.86 |
| 108.14 | 1.18 | 1.18 |
| 230.31 | 2.61 | 2.61 |
| 295.45 | 2.85 | 2.85 |
| 150.22 | 2.82 | 2.82 |
| 404.50 | 5.39 | 5.39 |
| 237.73 | 2.90 | 2.90 |
| 371.35 | 2.48 | 2.48 |
| 333.14 | -0.46 | -0.46 |
| 76.10 | -0.64 | -0.64 |
| 198.31 | 0.74 | 0.74 |
| 102.09 | -1.62 | -1.62 |
| 608.69 | 4.17 | 4.17 |
| 211.26 | 1.13 | 1.13 |
| 206.33 | 2.79 | 2.79 |
| 226.32 | 2.93 | 2.93 |
| 299.50 | 4.58 | 4.58 |
| 354.10 | -1.22 | -1.22 |
| 190.21 | -0.96 | -0.96 |
| 230.26 | 3.04 | 3.04 |
| 276.21 | 3.21 | 3.21 |
| 401.44 | 1.90 | 1.90 |
| 287.30 | 0.64 | 0.64 |
| 326.47 | 4.44 | 4.44 |
| 298.45 | 4.49 | 4.49 |
| 231.30 | 1.55 | 1.55 |
| 174.20 | 1.80 | 1.80 |
| 477.05 | 5.09 | 5.09 |
| 259.26 | 0.03 | 0.03 |
| 392.41 | 2.08 | 2.08 |
| 305.21 | 1.93 | 1.93 |
| 375.49 | 2.59 | 2.59 |
| 121.16 | -0.67 | -0.67 |
| 284.48 | 6.33 | 6.33 |
| 314.37 | 2.96 | 2.96 |
| 198.14 | 0.19 | 0.19 |
| 495.64 | 5.27 | 5.27 |
| 342.30 | -5.40 | -5.40 |
| 470.33 | 3.20 | 3.20 |
| 269.39 | 3.66 | 3.66 |
| 246.19 | -1.68 | -1.68 |
| 308.31 | 2.76 | 2.76 |
| 309.45 | 4.19 | 4.19 |
| 209.25 | 2.55 | 2.55 |
| 171.24 | 1.37 | 1.37 |
| 421.90 | 3.09 | 3.09 |
| 296.55 | 3.62 | 3.62 |
| 407.99 | 4.46 | 4.46 |
| 160.24 | 0.64 | 0.64 |
| 198.22 | 0.43 | 0.43 |
| 318.76 | 3.81 | 3.81 |
| 221.30 | 2.49 | 2.49 |
| 262.35 | 2.21 | 2.21 |
| 452.49 | 2.37 | 2.37 |
| 224.22 | -0.71 | -0.71 |
| 270.38 | 2.92 | 2.92 |
| 346.11 | ||
| 304.54 | 6.46 | 6.46 |
| 237.30 | 1.45 | 1.45 |
| 254.29 | 3.11 | 3.11 |
| 257.29 | 2.19 | 2.19 |
| 375.56 | 5.04 | 5.04 |
| 384.44 | 2.12 | 2.12 |
| 384.65 | 7.62 | 7.62 |
| 472.75 | 9.06 | 9.06 |
| 427.55 | 5.29 | 5.29 |
| 145.16 | 1.94 | 1.94 |
| 380.66 | 0.82 | 0.82 |
| 247.14 | 0.52 | 0.52 |
| 396.95 | 3.15 | 3.15 |
| 262.36 | 2.99 | 2.99 |
| 296.33 | 3.06 | 3.06 |
| 386.59 | 4.90 | 4.90 |
| 136.20 | 0.69 | 0.69 |
| 284.38 | 2.17 | 2.17 |
| 249.32 | 2.47 | 2.47 |
| 152.15 | -2.95 | -2.95 |
| 378.43 | 3.52 | 3.52 |
| 181.22 | 0.57 | 0.57 |
| 246.19 | -1.69 | -1.69 |
| 812.02 | 4.93 | 4.93 |
| 409.43 | 4.89 | 4.89 |
| 122.13 | 0.18 | 0.18 |
| 304.44 | 4.02 | 4.02 |
| 152.15 | 1.18 | 1.18 |
| 161.20 | -1.81 | -1.81 |
| 402.49 | 2.13 | 2.13 |
| 245.33 | 2.35 | 2.35 |
| 521.44 | 4.87 | 4.87 |
| 498.58 | 2.58 | 2.58 |
| 258.49 | 3.52 | 3.52 |
| 609.74 | 6.70 | 6.70 |
| 240.35 | 3.17 | 3.17 |
| 235.33 | 2.62 | 2.62 |
| 397.48 | 4.34 | 4.34 |
| 312.48 | 5.02 | 5.02 |
| 293.45 | 4.87 | 4.87 |
| 205.26 | 1.28 | 1.28 |
| 448.95 | 5.68 | 5.68 |
| 312.41 | 1.29 | 1.29 |
| 357.49 | 3.34 | 3.34 |
| 215.23 | -0.37 | -0.37 |
| 192.12 | -1.25 | -1.25 |
| 429.13 | 6.12 | 6.12 |
| 372.81 | 3.14 | 3.14 |
| 540.71 | 1.43 | 1.43 |
| 240.44 | 2.64 | 2.64 |
| 249.27 | 3.60 | 3.60 |
| 170.21 | -0.13 | -0.13 |
| 291.44 | 3.47 | 3.47 |
| 309.41 | 2.27 | 2.27 |
| 377.51 | 2.78 | 2.78 |
| 258.23 | 2.31 | 2.31 |
| 242.27 | 3.67 | 3.67 |
| 154.12 | -0.28 | -0.28 |
| 324.42 | 3.17 | 3.17 |
| 457.61 | 6.26 | 6.26 |
| 532.47 | 4.46 | 4.46 |
| 220.23 | 0.83 | 0.83 |
| 338.46 | 2.84 | 2.84 |
| 269.39 | 0.84 | 0.84 |
| 175.24 | 0.94 | 0.94 |
| 109.13 | 0.25 | 0.25 |
| 255.27 | 2.97 | 2.97 |
| 495.75 | 6.88 | 6.88 |
| 345.40 | 2.55 | 2.55 |
| 371.25 | ||
| 169.18 | 0.08 | 0.08 |
| 430.54 | 2.72 | 2.72 |
| 251.71 | 2.90 | 2.90 |
| 253.74 | 2.21 | 2.21 |
| 399.63 | 5.04 | 5.04 |
| 261.71 | 3.37 | 3.37 |
| 325.50 | 5.34 | 5.34 |
| 615.63 | -8.86 | -8.86 |
| 288.39 | 2.58 | 2.58 |
| 180.20 | 1.96 | 1.96 |
| 200.24 | 2.97 | 2.97 |
| 312.45 | 3.88 | 3.88 |
| 307.29 | 2.23 | 2.23 |
| 270.37 | 3.82 | 3.82 |
| 408.58 | 3.45 | 3.45 |
| 86.14 | -0.82 | -0.82 |
| 207.27 | 2.44 | 2.44 |
| 151.93 | ||
| 461.56 | 5.86 | 5.86 |
| 152.18 | 0.64 | 0.64 |
| 225.21 | -1.33 | -1.33 |
| 324.45 | 0.61 | 0.61 |
| 149.21 | 0.11 | 0.11 |
| 129.17 | -1.03 | -1.03 |
| 318.39 | 1.06 | 1.06 |
| 457.48 | 0.19 | 0.19 |
| 516.72 | 5.67 | 5.67 |
| 584.66 | -1.51 | -1.51 |
| 414.48 | 2.48 | 2.48 |
| 211.22 | 1.62 | 1.62 |
| 394.44 | 0.62 | 0.62 |
| 390.41 | 3.17 | 3.17 |
| 154.12 | 0.80 | 0.80 |
| 608.55 | -1.09 | -1.09 |
| 136.11 | 0.06 | 0.06 |
| 847.02 | 4.62 | 4.62 |
| 697.78 | 4.75 | 4.75 |
| 490.63 | 3.07 | 3.07 |
| 479.53 | 3.68 | 3.68 |
| 301.47 | 4.33 | 4.33 |
| 281.44 | 4.57 | 4.57 |
| 376.14 | 4.56 | 4.56 |
| 317.47 | 4.24 | 4.24 |
| 388.85 | 2.79 | 2.79 |
| 281.40 | 3.89 | 3.89 |
| 315.46 | 5.56 | 5.56 |
| 391.47 | 4.41 | 4.41 |
| 337.57 | 5.56 | 5.56 |
| 156.61 | 2.66 | 2.66 |
| 764.95 | 3.25 | 3.25 |
| 494.53 | 2.94 | 2.94 |
| 345.42 | 2.90 | 2.90 |
| 356.51 | 5.35 | 5.35 |
| 446.51 | 3.66 | 3.66 |
| 430.55 | 2.77 | 2.77 |
| 284.25 | 3.24 | 3.24 |
| 310.34 | 0.88 | 0.88 |
| 253.26 | -0.90 | -0.90 |
| 307.33 | -2.21 | -2.21 |
| 424.54 | 3.05 | 3.05 |
| 265.36 | 0.61 | 0.61 |
| 450.71 | 9.16 | 9.16 |
| 176.12 | -1.41 | -1.41 |
| 289.38 | 1.93 | 1.93 |
| 156.27 | 2.44 | 2.44 |
| 207.23 | -3.26 | -3.26 |
| 404.82 | ||
| 353.51 | 5.22 | 5.22 |
| 302.46 | 5.99 | 5.99 |
| 221.21 | -3.08 | -3.08 |
| 354.81 | 2.56 | 2.56 |
| 656.66 | 2.75 | 2.75 |
| 284.38 | 1.41 | 1.41 |
| 311.36 | 0.77 | 0.77 |
| 475.59 | -3.20 | -3.20 |
| 360.24 | 0.60 | 0.60 |
| 392.47 | 1.75 | 1.75 |
| 268.27 | -2.71 | -2.71 |
| 943.09 | 0.04 | 0.04 |
| 340.44 | 2.70 | 2.70 |
| 179.17 | -3.25 | -3.25 |
| 492.59 | 5.63 | 5.63 |
| 196.16 | -3.49 | -3.49 |
| 524.87 | 11.54 | 11.54 |
| 251.05 | ||
| 778.95 | 4.75 | 4.75 |
| 397.52 | 4.93 | 4.93 |
| 285.32 | 0.37 | 0.37 |
| 147.13 | -0.74 | -0.74 |
| 420.63 | 5.11 | 5.11 |
| 282.34 | 2.39 | 2.39 |
| 254.25 | -2.21 | -2.21 |
| 328.48 | 4.50 | 4.50 |
| 376.47 | 2.78 | 2.78 |
| 180.16 | -3.22 | -3.22 |
| 245.37 | 3.30 | 3.30 |
| 306.37 | 1.07 | 1.07 |
| 282.30 | 2.55 | 2.55 |
| 145.16 | -0.53 | -0.53 |
| 142.20 | -0.20 | -0.20 |
| 225.29 | 1.13 | 1.13 |
| 368.50 | 4.73 | 4.73 |
| 412.64 | 6.07 | 6.07 |
| 210.66 | ||
| 314.43 | 3.83 | 3.83 |
| 494.53 | 2.99 | 2.99 |
| 214.05 | 3.25 | 3.25 |
| 384.52 | 4.43 | 4.43 |
| 810.47 | 5.72 | 5.72 |
| 1056.24 | ||
| 195.22 | 0.74 | 0.74 |
| 494.58 | 3.44 | 3.44 |
| 484.97 | 4.05 | 4.05 |
| 205.25 | -1.14 | -1.14 |
| 436.52 | 2.50 | 2.50 |
| 451.62 | 3.19 | 3.19 |
| 340.46 | 4.06 | 4.06 |
| 1030.30 | ||
| 513.68 | 5.95 | 5.95 |
| 437.78 | 7.02 | 7.02 |
| 325.46 | 2.29 | 2.29 |
| 290.38 | 2.03 | 2.03 |
| 291.39 | 2.33 | 2.33 |
| 340.44 | 3.95 | 3.95 |
| 348.51 | 3.48 | 3.48 |
| 472.45 | 2.01 | 2.01 |
| 309.48 | 5.02 | 5.02 |
| 318.53 | 4.72 | 4.72 |
| 492.69 | 4.26 | 4.26 |
| 298.35 | 1.02 | 1.02 |
| 529.46 | 1.66 | 1.66 |
| 429.60 | 5.41 | 5.41 |
| 484.39 | 3.91 | 3.91 |
| 261.39 | 2.71 | 2.71 |
| 225.20 | -1.63 | -1.63 |
| 292.77 | 3.73 | 3.73 |
| 295.39 | 2.98 | 2.98 |
| 313.29 | 3.11 | 3.11 |
| 426.59 | 3.37 | 3.37 |
| 165.19 | 1.18 | 1.18 |
| 296.39 | 3.42 | 3.42 |
| 280.31 | 0.87 | 0.87 |
| 263.36 | 3.52 | 3.52 |
| 300.36 | 2.06 | 2.06 |
| 182.18 | 1.40 | 1.40 |
| 383.53 | 4.45 | 4.45 |
| 332.46 | 2.85 | 2.85 |
| 127.17 | 1.45 | 1.45 |
| 439.58 | 2.41 | 2.41 |
| 313.40 | 2.98 | 2.98 |
| 265.25 | -1.53 | -1.53 |
| 272.14 | 2.56 | 2.56 |
| 309.35 | 1.30 | 1.30 |
| 357.93 | 5.50 | 5.50 |
| 577.73 | 2.52 | 2.52 |
| 219.28 | 2.86 | 2.86 |
| 187.24 | 1.01 | 1.01 |
| 440.51 | 4.22 | 4.22 |
| 828.01 | 3.16 | 3.16 |
| 452.54 | 4.68 | 4.68 |
| 213.19 | -0.46 | -0.46 |
| 178.24 | 1.56 | 1.56 |
| 554.73 | -1.63 | -1.63 |
| 261.37 | 3.84 | 3.84 |
| 446.56 | 3.99 | 3.99 |
| 271.40 | 3.34 | 3.34 |
| 355.39 | 3.45 | 3.45 |
| 440.77 | 1.92 | 1.92 |
| 501.51 | 5.54 | 5.54 |
| 173.21 | 0.77 | 0.77 |
| 460.57 | 3.31 | 3.31 |
| 304.82 | 2.74 | 2.74 |
| 461.50 | 3.28 | 3.28 |
| 273.30 | 3.49 | 3.49 |
| 217.30 | 2.22 | 2.22 |
| 355.82 | 1.61 | 1.61 |
| 475.34 | 2.08 | 2.08 |
| 374.37 | 2.53 | 2.53 |
| 205.24 | 0.60 | 0.60 |
| 422.42 | 2.44 | 2.44 |
| 446.64 | 4.12 | 4.12 |
| 1239.45 | ||
| 145.25 | 1.27 | 1.27 |
| 408.88 | 2.27 | 2.27 |
| 415.43 | 3.75 | 3.75 |
| 170.25 | 1.47 | 1.47 |
| 392.18 | ||
| 405.97 | 6.56 | 6.56 |
| 324.38 | 2.52 | 2.52 |
| 889.02 | 8.61 | 8.61 |
| 1390.73 | ||
| 742.68 | -2.69 | -2.69 |
| 365.41 | -0.07 | -0.07 |
| 280.52 | -0.65 | -0.65 |
| 465.52 | 3.31 | 3.31 |
| 417.82 | 5.23 | 5.23 |
| 266.39 | ||
| 473.38 | 4.29 | 4.29 |
| 582.97 | 4.32 | 4.32 |
| 342.48 | 4.00 | 4.00 |
| 332.42 | 1.45 | 1.45 |
| 530.51 | 5.75 | 5.75 |
| 439.58 | 5.30 | 5.30 |
| 604.72 | -0.04 | -0.04 |
| 434.53 | 4.60 | 4.60 |
| 341.37 | 3.30 | 3.30 |
| 315.22 | -1.66 | -1.66 |