Assay Report Card

Basic Information

ID: ALA5291814

Type: Functional

Description: Antagonist activity at human HTR1A in an in vitro cell-based assay measured by fluorescent imaging plate reader

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
383.411.781.78
357.793.933.93
331.351.581.58
135.211.581.58
280.423.883.88
303.291.771.77
441.554.374.37
430.382.882.88
284.753.153.15
267.371.611.61
249.352.152.15
268.364.834.83
167.302.422.42
252.271.771.77
914.196.186.18
804.034.644.64
305.160.290.29
236.28-1.42-1.42
222.25-0.86-0.86
290.321.261.26
454.615.095.09
398.403.703.70
414.533.373.37
180.161.311.31
407.514.954.95
259.352.582.58
266.341.381.38
416.361.891.89
252.350.600.60
375.401.981.98
401.442.372.37
211.261.131.13
297.75-0.35-0.35
330.751.891.89
248.722.522.52
255.321.531.53
250.280.860.86
309.334.444.44
253.281.371.37
326.833.723.72
263.383.833.83
278.341.481.48
226.281.181.18
226.281.181.18
198.220.500.50
315.723.043.04
280.310.870.87
224.260.960.96
214.250.090.09
393.474.514.51
303.143.613.61
250.343.573.57
232.281.861.86
302.241.991.99
395.432.422.42
211.220.440.44
267.332.852.85
375.874.434.43
354.495.655.65
266.302.652.65
444.49-0.14-0.14
395.483.223.22
223.282.682.68
137.14-0.31-0.31
258.230.090.09
255.272.292.29
494.013.643.64
441.581.981.98
243.394.334.33
182.190.070.07
267.25-1.98-1.98
370.595.895.89
369.373.523.52
287.22-0.05-0.05
299.371.501.50
318.874.894.89
266.393.533.53
319.884.814.81
329.373.333.33
358.854.184.18
234.342.582.58
473.596.086.08
371.526.006.00
654.613.193.19
410.493.593.59
299.802.002.00
853.923.743.74
354.493.483.48
305.503.203.20
243.312.532.53
276.751.741.74
316.430.500.50
248.331.911.91
924.090.710.71
416.136.456.45
807.893.263.26
275.351.771.77
379.504.364.36
404.554.204.20
228.252.032.03
274.803.823.82
187.201.021.02
339.483.363.36
264.322.472.47
333.361.611.61
206.283.073.07
313.292.552.55
281.272.382.38
270.723.133.13
178.273.643.64
331.351.581.58
308.383.793.79
749.001.901.90
733.941.791.79
314.474.724.72
309.434.014.01
344.855.385.38
306.280.740.74
426.494.834.83
507.18-1.63-1.63
324.403.813.81
399.442.872.87
393.443.413.41
144.212.292.29
776.874.564.56
463.805.945.94
352.772.812.81
244.263.683.68
284.434.244.24
242.703.063.06
151.161.351.35
194.19-1.03-1.03
403.983.943.94
286.722.452.45
356.424.374.37
297.144.414.41
254.293.113.11
238.160.070.07
123.110.780.78
165.191.451.45
348.401.131.13
376.451.601.60
321.163.103.10
316.162.632.63
310.405.195.19
670.863.093.09
253.270.830.83
381.383.513.51
260.382.852.85
172.182.012.01
471.696.456.45
257.383.083.08
356.453.163.16
281.362.842.84
351.411.951.95
163.20-0.49-0.49
314.362.562.56
241.680.820.82
382.543.953.95
516.869.919.91
246.312.792.79
291.732.852.85
387.441.061.06
209.321.311.31
123.11-0.42-0.42
396.450.590.59
354.471.701.70
337.351.121.12
383.47-0.31-0.31
371.872.362.36
287.363.383.38
287.414.994.99
335.193.133.13
277.414.174.17
295.411.321.32
341.453.243.24
358.431.771.77
267.24-0.20-0.20
381.914.304.30
235.331.341.34
255.363.723.72
336.432.372.37
284.434.244.24
360.451.561.56
325.452.372.37
343.224.234.23
374.481.801.80
414.353.443.44
230.102.362.36
265.362.482.48
371.282.682.68
272.393.613.61
255.363.353.35
151.251.911.91
308.773.583.58
277.414.214.21
171.160.090.09
263.384.304.30
275.404.554.55
189.220.160.16
360.844.684.68
183.210.350.35
244.292.672.67
295.302.972.97
281.234.154.15
296.154.364.36
241.293.753.75
261.373.923.92
218.100.860.86
141.170.450.45
203.241.331.33
334.383.103.10
264.372.622.62
136.200.840.84
213.661.861.86
451.481.721.72
298.392.202.20
372.553.813.81
222.242.852.85
252.272.862.86
229.26-0.59-0.59
239.311.311.31
312.443.443.44
331.874.884.88
270.763.633.63
420.324.534.53
500.632.592.59
379.502.892.89
437.534.314.31
334.783.293.29
310.784.634.63
373.954.584.58
628.814.334.33
429.564.604.60
256.102.012.01
234.202.782.78
212.230.620.62
308.380.530.53
303.834.194.19
160.221.231.23
299.35-0.18-0.18
608.694.174.17
199.16-1.10-1.10
389.412.212.21
327.473.373.37
284.752.612.61
270.351.781.78
612.633.633.63
505.464.184.18
303.362.062.06
294.753.273.27
454.450.270.27
291.381.221.22
230.263.043.04
378.324.454.45
243.22-2.56-2.56
276.213.213.21
179.312.692.69
381.695.805.80
219.241.461.46
306.245.185.18
158.16-1.94-1.94
194.15-2.08-2.08
319.253.933.93
424.524.744.74
312.422.322.32
157.22-0.21-0.21
246.31-0.28-0.28
320.320.660.66
361.833.553.55
182.17-0.23-0.23
327.813.773.77
404.493.803.80
621.934.634.63
263.793.963.96
235.07-1.66-1.66
180.251.151.15
408.522.342.34
435.44-1.17-1.17
546.59-1.30-1.30
424.502.572.57
292.381.701.70
220.281.371.37
416.655.705.70
279.341.811.81
381.453.773.77
211.22-0.50-0.50
278.403.923.92
458.585.355.35
470.616.336.33
218.260.540.54
244.320.800.80
218.261.471.47
246.101.551.55
290.793.403.40
368.525.115.11
314.372.962.96
204.31-0.29-0.29
588.561.341.34
1449.27
249.10-1.27-1.27
1202.63
157.210.840.84
365.842.712.71
321.340.540.54
277.193.003.00
171.241.901.90
263.20-1.29-1.29
239.753.303.30
271.403.383.38
374.913.063.06
285.372.202.20
250.203.043.04
337.46-0.77-0.77
484.645.105.10
214.272.192.19
400.984.244.24
307.403.253.25
501.675.515.51
178.190.420.42
501.482.702.70
554.59-1.20-1.20
283.11-0.37-0.37
301.392.962.96
410.511.521.52
395.42-0.17-0.17
504.64-0.02-0.02
226.282.642.64
720.965.915.91
446.914.284.28
171.241.371.37
211.331.581.58
319.412.922.92
229.63-1.08-1.08
305.423.793.79
260.313.173.17
551.634.204.20
179.312.552.55
270.213.253.25
151.211.071.07
147.20-0.21-0.21
300.752.472.47
352.744.094.09
270.213.003.00
282.223.543.54
705.655.585.58
312.412.532.53
218.250.980.98
198.220.430.43
339.442.512.51
286.465.515.51
317.485.775.77
224.22-0.71-0.71
427.460.100.10
319.230.500.50
382.894.894.89
388.903.153.15
300.753.373.37
139.150.400.40
337.381.641.64
214.23-0.25-0.25
366.554.834.83
197.190.050.05
237.301.451.45
610.676.326.32
440.464.034.03
514.637.267.26
266.344.604.60
277.505.305.30
261.091.881.88
200.283.183.18
301.392.812.81
434.472.252.25
339.39-0.24-0.24
356.513.623.62
307.392.572.57
248.311.681.68
131.180.590.59
290.271.551.55
432.604.194.19
328.431.171.17
307.424.954.95
338.770.920.92
415.50-0.32-0.32
159.231.081.08
418.574.594.59
287.362.352.35
352.484.364.36
268.741.401.40
228.293.373.37
293.324.034.03
287.453.943.94
364.423.043.04
445.552.082.08
231.263.253.25
253.721.721.72
365.410.020.02
411.573.493.49
343.473.493.49
246.352.732.73
238.240.960.96
204.231.301.30
298.302.752.75
354.193.913.91
289.362.032.03
179.220.720.72
288.443.903.90
311.473.963.96
290.370.260.26
217.271.771.77
225.160.970.97
351.843.333.33
212.252.982.98
500.438.648.64
294.362.412.41
334.422.302.30
313.793.433.43
180.17-1.04-1.04
118.16-0.22-0.22
413.565.735.73
405.450.880.88
309.494.404.40
337.464.504.50
291.444.714.71
424.532.442.44
327.343.053.05
462.51-0.23-0.23
348.432.532.53
299.413.433.43
384.25
704.874.214.21
429.564.044.04
332.35-2.93-2.93
416.522.382.38
344.504.844.84
367.882.092.09
310.834.024.02
176.180.600.60
317.433.243.24
261.714.094.09
270.341.231.23
220.322.322.32
339.420.700.70
397.484.344.34
308.422.952.95
443.643.473.47
284.454.254.25
193.252.232.23
262.220.840.84
302.413.973.97
378.410.490.49
301.734.344.34
167.210.650.65
359.452.992.99
397.766.526.52
388.821.571.57
348.454.024.02
192.262.512.51
260.332.022.02
405.501.241.24
188.221.891.89
212.253.043.04
255.372.652.65
374.914.044.04
392.503.413.41
266.340.450.45
412.536.686.68
372.813.143.14
452.605.225.22
317.222.452.45
240.312.822.82
170.21-0.13-0.13
378.113.193.19
346.855.045.04
380.471.351.35
473.417.497.49
380.494.474.47
315.484.274.27
362.412.422.42
265.362.692.69
82.110.720.72
191.14-1.28-1.28
163.20-0.49-0.49
273.724.164.16
221.301.051.05
273.242.552.55
767.911.521.52
433.353.723.72
199.321.561.56
205.260.240.24
324.34-0.80-0.80
240.374.214.21
195.692.592.59
416.473.093.09
349.410.320.32
510.835.455.45
572.886.116.11
344.412.222.22
430.542.722.72
415.833.473.47
251.712.902.90
169.571.771.77
373.462.072.07
363.503.313.31
384.432.602.60
307.392.772.77
273.362.012.01
260.313.173.17
206.283.073.07
360.382.312.31
314.475.855.85
413.432.882.88
387.483.743.74
325.505.345.34
484.50-7.29-7.29
416.584.854.85
302.464.274.27
211.271.801.80
994.21-3.04-3.04
585.61-8.42-8.42
581.58-8.16-8.16
293.372.932.93
266.341.121.12
323.421.631.63
165.241.331.33
563.630.750.75
279.864.744.74
137.160.320.32
315.421.161.16
488.023.313.31
407.322.022.02
461.565.865.86
288.433.883.88
425.923.353.35
230.681.681.68
822.954.344.34
418.452.972.97
392.471.901.90
255.23-1.97-1.97
225.21-1.33-1.33
339.37-0.40-0.40
129.17-1.03-1.03
444.44-0.35-0.35
454.52-0.64-0.64
424.39-0.54-0.54
453.882.692.69
480.57-1.28-1.28
602.687.337.33
169.180.090.09
332.31-3.58-3.58
444.44-0.21-0.21
166.251.281.28
828.013.013.01
362.471.781.78
424.095.465.46
315.684.074.07
336.453.333.33
406.55-0.86-0.86
366.845.515.51
135.13-0.11-0.11
202.641.071.07
211.221.621.62
180.17-1.04-1.04
204.302.152.15
259.22-2.70-2.70
299.371.931.93
369.491.291.29
129.09-0.51-0.51
308.333.613.61
336.302.902.90
136.110.060.06
179.20-0.78-0.78
164.202.092.09
534.434.954.95
500.584.434.43
228.253.463.46
392.584.484.48
318.301.741.74
337.464.224.22
384.263.963.96
419.534.914.91
496.633.903.90
265.343.243.24
198.18-1.03-1.03
422.924.274.27
474.591.611.61
558.656.316.31
244.21-3.17-3.17
408.882.272.27
304.322.982.98
611.746.486.48
344.462.732.73
338.443.463.46
481.552.402.40
212.250.940.94
346.342.182.18
383.382.882.88
342.30-5.40-5.40
434.502.422.42
324.403.813.81
269.310.380.38
434.502.272.27
428.544.784.78
442.42-0.44-0.44
170.241.381.38
530.663.013.01
305.342.642.64
302.282.522.52
391.296.116.11
349.525.405.40
293.734.164.16
246.351.771.77
324.464.054.05
289.740.880.88
335.883.783.78
387.53-1.31-1.31
277.271.151.15
650.983.953.95
392.584.484.48
469.391.691.69
645.61-8.56-8.56
492.534.284.28
315.412.972.97
366.482.172.17
300.403.593.59
789.10-0.03-0.03
149.241.971.97
167.211.421.42
360.372.572.57
268.27-1.18-1.18
465.531.301.30
410.584.984.98
324.402.212.21
165.241.331.33
464.860.260.26
438.522.572.57
220.313.463.46
301.391.731.73
295.854.174.17
257.260.810.81
423.470.480.48
410.43-0.05-0.05
253.353.243.24
575.63-1.40-1.40
460.512.432.43
420.51-1.60-1.60
285.69-0.30-0.30
441.40-0.04-0.04
390.965.565.56
776.874.564.56
343.905.105.10
551.773.293.29
363.390.150.15
371.392.582.58
402.492.562.56
435.481.271.27
537.584.644.64
344.31-5.76-5.76
634.734.574.57
320.055.935.93
427.46-0.54-0.54
538.584.934.93
645.68-1.11-1.11
473.45-0.73-0.73
432.563.133.13
421.421.631.63
116.07-0.29-0.29
186.241.561.56
385.382.462.46
388.423.203.20
347.400.440.44
465.953.363.36
455.47-0.62-0.62
813.983.623.62
289.163.593.59
303.360.920.92
303.68-0.35-0.35
780.952.222.22
424.990.390.39
378.523.173.17
138.06-0.09-0.09
192.261.591.59
331.300.010.01
321.833.673.67
398.421.391.39
359.350.760.76
450.355.045.04
386.452.382.38
414.344.874.87
365.21-1.72-1.72
371.823.183.18
510.48-0.17-0.17
414.503.123.12
257.25-1.76-1.76
450.934.114.11
610.714.954.95
227.742.762.76
1139.76
532.574.464.46
485.954.394.39
270.762.422.42
328.451.671.67
477.564.264.26
305.372.372.37
205.302.602.60
486.444.614.61
243.173.053.05
341.430.280.28
404.423.073.07
296.414.034.03
504.603.823.82
488.583.703.70
387.725.865.86
821.14-1.63-1.63
521.054.094.09
578.664.164.16
284.362.212.21
370.534.504.50
558.604.174.17
273.741.621.62
502.583.523.52
380.875.875.87
183.251.131.13
224.260.960.96
329.443.473.47
369.514.714.71
415.573.153.15
528.546.586.58
422.492.442.44
557.610.830.83
431.952.242.24
416.512.332.33
241.240.530.53
228.21-2.14-2.14
310.443.923.92
364.535.235.23
231.251.421.42
344.503.943.94
471.55-0.73-0.73
228.220.180.18
307.444.424.42
612.650.330.33
177.251.741.74
340.494.834.83
254.29-0.19-0.19
239.311.911.91
289.423.923.92
353.534.114.11
529.794.414.41
388.462.582.58
177.250.980.98
474.552.222.22
183.682.622.62
433.046.546.54
319.253.933.93
314.261.741.74
181.21-0.60-0.60
753.008.718.71
354.37-1.44-1.44
167.210.770.77
291.392.182.18
278.424.364.36
357.322.712.71
274.803.823.82
380.461.871.87
382.544.264.26
421.474.524.52
190.16-1.03-1.03
215.291.421.42
322.504.394.39
339.484.284.28
288.182.862.86
349.394.444.44
837.062.212.21
193.200.890.89
356.230.400.40
492.694.264.26
263.382.632.63
527.570.470.47
390.523.583.58
216.282.142.14
572.565.715.71
185.232.152.15
376.422.352.35
321.164.094.09
429.605.415.41
436.964.194.19
386.484.644.64
420.851.491.49
396.573.893.89
298.351.531.53
308.252.242.24
379.891.601.60
603.752.832.83
325.844.334.33
177.462.132.13
190.161.851.85
340.464.374.37
465.571.741.74
255.792.832.83
276.383.483.48
218.270.490.49
266.26-1.19-1.19
434.502.472.47
257.22-1.45-1.45
371.832.302.30
416.136.456.45
349.821.521.52
345.851.901.90
466.41-2.88-2.88
354.473.093.09
279.383.963.96
392.881.901.90
365.483.343.34
482.634.774.77
431.562.662.66
295.343.433.43
314.411.461.46
308.423.723.72
193.201.271.27
392.523.773.77
813.982.622.62
540.704.704.70
330.516.476.47
1346.38
385.492.982.98
312.453.883.88
452.414.754.75
231.291.621.62
382.891.181.18
383.470.730.73
326.441.551.55
501.515.545.54
283.312.752.75
470.542.672.67
283.330.760.76
313.340.950.95
527.533.853.85
345.874.524.52
238.333.273.27
379.503.863.86
246.311.811.81
144.13-0.11-0.11
284.444.314.31
380.533.893.89
339.33-0.80-0.80
293.454.504.50
426.591.571.57
372.556.266.26
411.474.634.63
2296.97
398.687.727.72
416.874.484.48
563.676.126.12
331.471.321.32
466.462.632.63
285.774.264.26
441.233.013.01
406.422.802.80
506.614.944.94
540.023.913.91
389.430.710.71
666.915.485.48
499.624.514.51
572.754.734.73
520.503.403.40
490.442.352.35
443.313.393.39
198.23-0.37-0.37
499.435.015.01
576.733.683.68
511.580.840.84
740.761.541.54