Assay Report Card

Basic Information

ID: ALA5291845

Type: Functional

Description: Antagonist activity at human NR1I2 in an in vitro cell free assay measured by time-resolved fluorescence resonance energy transfer method

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
135.211.581.58
441.554.374.37
430.382.882.88
249.352.152.15
252.271.771.77
804.034.644.64
454.615.095.09
398.403.703.70
416.361.891.89
581.671.991.99
263.383.833.83
212.250.790.79
375.874.434.43
278.445.665.66
395.483.223.22
223.282.682.68
272.371.091.09
243.394.334.33
267.25-1.98-1.98
266.393.533.53
232.281.351.35
276.423.753.75
371.526.006.00
654.613.193.19
410.493.593.59
354.493.483.48
316.430.500.50
308.342.522.52
275.351.771.77
228.252.032.03
440.954.634.63
339.483.363.36
264.322.472.47
333.361.611.61
206.283.073.07
383.41-0.56-0.56
314.504.274.27
733.941.791.79
398.483.333.33
265.351.991.99
426.494.834.83
352.473.253.25
399.442.872.87
393.443.413.41
404.352.042.04
260.251.111.11
179.262.032.03
463.805.945.94
238.332.852.85
351.351.801.80
151.161.351.35
254.283.403.40
348.401.131.13
395.462.552.55
260.382.852.85
356.453.163.16
336.484.144.14
357.442.492.49
207.231.311.31
163.20-0.49-0.49
131.13-0.62-0.62
575.695.705.70
241.680.820.82
339.393.863.86
382.543.953.95
246.312.792.79
146.24-1.92-1.92
291.732.852.85
230.313.303.30
396.450.590.59
407.585.685.68
354.471.701.70
337.351.121.12
352.452.702.70
383.47-0.31-0.31
412.565.805.80
277.414.174.17
341.453.243.24
277.413.043.04
381.914.304.30
323.130.910.91
255.363.723.72
405.442.362.36
414.353.443.44
265.362.482.48
315.371.051.05
277.414.214.21
189.220.160.16
183.210.350.35
367.810.620.62
295.302.972.97
296.154.364.36
296.413.613.61
218.100.860.86
136.200.840.84
213.661.861.86
387.480.720.72
475.364.434.43
229.26-0.59-0.59
312.443.443.44
331.874.884.88
270.763.633.63
386.534.664.66
379.502.892.89
406.483.743.74
211.180.020.02
429.564.604.60
234.202.782.78
308.380.530.53
347.22-1.86-1.86
303.834.194.19
260.382.852.85
295.381.531.53
160.221.231.23
299.35-0.18-0.18
199.16-1.10-1.10
327.473.373.37
284.752.612.61
586.208.958.95
612.633.633.63
454.450.270.27
369.473.463.46
230.263.043.04
378.324.454.45
219.241.461.46
142.16-0.91-0.91
158.16-1.94-1.94
194.15-2.08-2.08
319.253.933.93
317.233.843.84
246.31-0.28-0.28
182.17-0.23-0.23
404.493.803.80
621.934.634.63
263.793.963.96
435.44-1.17-1.17
546.59-1.30-1.30
368.302.012.01
220.281.371.37
292.141.761.76
470.616.336.33
218.261.471.47
290.793.403.40
314.372.962.96
588.561.341.34
348.442.122.12
1202.63
277.193.003.00
471.522.992.99
435.892.552.55
480.654.944.94
285.372.202.20
484.645.105.10
543.530.000.00
214.272.192.19
315.875.195.19
404.345.505.50
501.482.702.70
554.59-1.20-1.20
301.392.962.96
308.312.762.76
446.914.284.28
171.241.371.37
284.362.952.95
319.412.922.92
551.634.204.20
352.744.094.09
270.213.003.00
705.655.585.58
339.442.512.51
356.813.563.56
325.453.773.77
535.525.425.42
427.460.100.10
139.150.400.40
322.484.634.63
214.23-0.25-0.25
366.554.834.83
244.383.153.15
610.676.326.32
440.464.034.03
514.637.267.26
340.472.932.93
277.505.305.30
301.392.812.81
384.442.122.12
339.39-0.24-0.24
356.513.623.62
307.392.572.57
432.604.194.19
328.431.171.17
307.424.954.95
159.231.081.08
418.574.594.59
287.362.352.35
365.410.020.02
411.573.493.49
246.352.732.73
204.231.301.30
289.362.032.03
179.220.720.72
491.635.755.75
288.443.903.90
311.473.963.96
290.370.260.26
212.252.982.98
500.438.648.64
432.503.413.41
448.394.864.86
118.16-0.22-0.22
413.565.735.73
309.494.404.40
337.464.504.50
291.444.714.71
424.532.442.44
462.51-0.23-0.23
153.140.670.67
367.882.092.09
317.433.243.24
287.361.921.92
261.714.094.09
220.322.322.32
294.392.562.56
339.420.700.70
308.422.952.95
193.252.232.23
378.410.490.49
301.734.344.34
388.821.571.57
348.454.024.02
192.262.512.51
256.102.012.01
390.390.450.45
372.813.143.14
452.605.225.22
170.21-0.13-0.13
380.471.351.35
473.417.497.49
380.494.474.47
531.444.214.21
363.803.293.29
315.484.274.27
362.412.422.42
679.78-2.40-2.40
163.20-0.49-0.49
273.724.164.16
279.382.982.98
273.242.552.55
272.393.263.26
464.835.555.55
195.692.592.59
606.788.688.68
349.410.320.32
405.460.330.33
281.444.994.99
415.833.473.47
373.462.072.07
363.503.313.31
307.392.772.77
206.283.073.07
314.475.855.85
413.432.882.88
399.635.045.04
403.215.035.03
286.341.091.09
416.584.854.85
302.464.274.27
435.892.522.52
211.271.801.80
994.21-3.04-3.04
700.794.574.57
527.531.031.03
307.292.232.23
527.643.523.52
266.341.121.12
207.272.442.44
563.630.750.75
315.421.161.16
488.023.313.31
407.322.022.02
461.565.865.86
822.954.344.34
418.452.972.97
255.23-1.97-1.97
130.08-0.80-0.80
454.52-0.64-0.64
424.39-0.54-0.54
453.882.692.69
480.57-1.28-1.28
602.687.337.33
424.095.465.46
315.684.074.07
327.123.863.86
366.845.515.51
135.13-0.11-0.11
204.302.152.15
433.502.522.52
259.22-2.70-2.70
369.491.291.29
237.732.902.90
308.333.613.61
459.512.702.70
179.20-0.78-0.78
392.584.484.48
490.633.073.07
419.534.914.91
558.656.316.31
351.374.084.08
304.322.982.98
611.746.486.48
481.552.402.40
212.250.940.94
346.342.182.18
342.30-5.40-5.40
434.502.422.42
335.472.202.20
324.403.813.81
366.504.314.31
434.502.272.27
530.663.013.01
349.525.405.40
293.734.164.16
284.253.243.24
246.351.771.77
339.353.653.65
387.53-1.31-1.31
461.500.090.09
453.46-0.54-0.54
391.565.975.97
392.584.484.48
594.67-0.59-0.59
366.482.172.17
455.554.404.40
360.372.572.57
268.27-1.18-1.18
465.531.301.30
367.452.232.23
220.313.463.46
570.776.836.83
394.462.732.73
295.854.174.17
349.410.350.35
253.353.243.24
575.63-1.40-1.40
460.512.432.43
421.314.714.71
420.51-1.60-1.60
285.69-0.30-0.30
441.40-0.04-0.04
317.392.282.28
776.874.564.56
551.773.293.29
435.481.271.27
537.584.644.64
344.31-5.76-5.76
645.68-1.11-1.11
473.45-0.73-0.73
116.07-0.29-0.29
385.382.462.46
539.643.623.62
455.47-0.62-0.62
627.755.815.81
289.163.593.59
289.301.151.15
747.962.442.44
420.635.115.11
780.952.222.22
378.523.173.17
225.291.521.52
321.833.673.67
359.350.760.76
450.355.045.04
386.452.382.38
143.231.541.54
414.344.874.87
370.851.841.84
414.503.123.12
466.984.104.10
227.742.762.76
532.574.464.46
485.954.394.39
270.762.422.42
328.451.671.67
412.646.076.07
282.453.523.52
334.576.066.06
486.444.614.61
243.173.053.05
332.484.404.40
424.625.125.12
380.875.875.87
183.251.131.13
521.053.943.94
422.492.442.44
307.444.424.42
557.845.975.97
511.57-0.87-0.87
404.512.422.42
177.250.980.98
474.552.222.22
181.21-0.60-0.60
753.008.718.71
274.803.823.82
382.544.264.26
421.474.524.52
238.200.700.70
215.291.421.42
456.35-1.61-1.61
441.522.562.56
322.504.394.39
837.062.212.21
193.200.890.89
356.230.400.40
492.694.264.26
390.523.583.58
216.282.142.14
572.565.715.71
1058.05
185.232.152.15
376.422.352.35
321.164.094.09
515.54-2.49-2.49
236.310.160.16
436.964.194.19
454.875.645.64
342.864.204.20
386.484.644.64
242.240.090.09
312.763.823.82
396.573.893.89
298.351.531.53
221.302.742.74
325.844.334.33
450.535.745.74
340.464.374.37
465.571.741.74
370.494.194.19
244.27-0.75-0.75
295.454.684.68
218.270.490.49
266.26-1.19-1.19
294.351.191.19
257.22-1.45-1.45
371.832.302.30
349.821.521.52
400.656.596.59
345.851.901.90
466.41-2.88-2.88
354.473.093.09
279.342.892.89
556.661.321.32
203.24-1.24-1.24
249.31-0.05-0.05
288.393.053.05
392.881.901.90
141.262.342.34
365.483.343.34
145.541.151.15
482.634.774.77
298.363.763.76
295.343.433.43
264.321.891.89
308.423.723.72
440.514.224.22
193.201.271.27
468.596.206.20
248.202.002.00
482.825.695.69
291.693.483.48
330.516.476.47
385.492.982.98
563.586.326.32
312.453.883.88
406.501.711.71
546.944.514.51
452.414.754.75
402.503.133.13
231.291.621.62
395.383.333.33
284.36-2.67-2.67
383.470.730.73
574.994.994.99
501.515.545.54
522.57-3.16-3.16
283.330.760.76
313.340.950.95
412.884.514.51
527.533.853.85
238.333.273.27
379.503.863.86
246.311.811.81
144.13-0.11-0.11
284.444.314.31
374.372.532.53
380.533.893.89
358.442.572.57
339.33-0.80-0.80
469.955.165.16
426.591.571.57
415.433.753.75
713.1414.5714.57
411.474.634.63
416.874.484.48
868.468.668.66
466.462.632.63
285.774.264.26
441.233.013.01
406.422.802.80
506.614.944.94
666.915.485.48
499.624.514.51
572.754.734.73
520.503.403.40
443.313.393.39
217.22-1.83-1.83
280.411.651.65
530.515.755.75
434.534.604.60
398.503.583.58