Assay Report Card

Basic Information

ID: ALA5291861

Type: Functional

Description: Antagonist activity at human PGR in an in vitro cell free assay measured by time-resolved fluorescence resonance energy transfer method

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
369.341.701.70
319.341.271.27
135.211.581.58
303.291.771.77
441.554.374.37
430.382.882.88
249.352.152.15
167.302.422.42
252.271.771.77
804.034.644.64
305.160.290.29
236.28-1.42-1.42
222.25-0.86-0.86
266.340.450.45
266.341.381.38
416.361.891.89
375.401.981.98
401.442.372.37
211.261.131.13
330.751.891.89
248.722.522.52
264.311.171.17
250.280.860.86
581.671.991.99
263.383.833.83
278.341.481.48
226.281.181.18
226.281.181.18
212.250.790.79
198.220.500.50
267.311.671.67
224.260.960.96
214.250.090.09
393.474.514.51
303.143.613.61
232.281.861.86
211.220.440.44
276.381.961.96
375.874.434.43
354.495.655.65
278.445.665.66
395.483.223.22
137.14-0.31-0.31
255.272.292.29
272.371.091.09
243.394.334.33
182.190.070.07
267.25-1.98-1.98
287.22-0.05-0.05
266.393.533.53
232.281.351.35
319.884.814.81
276.423.753.75
371.526.006.00
654.613.193.19
410.493.593.59
354.493.483.48
316.430.500.50
248.331.911.91
308.342.522.52
924.090.710.71
416.136.456.45
807.893.263.26
236.302.732.73
275.351.771.77
228.252.032.03
440.954.634.63
339.483.363.36
264.322.472.47
333.361.611.61
281.272.382.38
178.273.643.64
331.351.581.58
383.41-0.56-0.56
308.383.793.79
278.363.953.95
314.504.274.27
733.941.791.79
384.594.164.16
426.564.134.13
309.434.014.01
265.351.991.99
426.494.834.83
352.473.253.25
313.403.193.19
507.18-1.63-1.63
399.442.872.87
393.443.413.41
404.352.042.04
260.251.111.11
179.262.032.03
463.805.945.94
238.332.852.85
351.351.801.80
352.772.812.81
244.263.683.68
151.161.351.35
254.283.403.40
403.983.943.94
254.293.113.11
238.160.070.07
281.313.043.04
165.191.451.45
348.401.131.13
316.162.632.63
310.405.195.19
505.642.402.40
260.382.852.85
172.182.012.01
257.383.083.08
357.442.492.49
259.142.762.76
207.231.311.31
163.20-0.49-0.49
131.13-0.62-0.62
575.695.705.70
241.680.820.82
339.393.863.86
382.543.953.95
247.342.212.21
146.24-1.92-1.92
291.732.852.85
209.321.311.31
123.11-0.42-0.42
230.313.303.30
396.450.590.59
407.585.685.68
387.913.783.78
354.471.701.70
337.351.121.12
352.452.702.70
383.47-0.31-0.31
287.363.383.38
412.565.805.80
287.414.994.99
335.193.133.13
278.310.190.19
277.414.174.17
341.453.243.24
381.914.304.30
323.130.910.91
235.331.341.34
255.363.723.72
336.432.372.37
405.442.362.36
414.353.443.44
265.362.482.48
371.282.682.68
315.371.051.05
151.251.911.91
277.414.214.21
146.210.260.26
171.160.090.09
263.384.304.30
189.220.160.16
183.210.350.35
367.810.620.62
244.292.672.67
355.875.185.18
295.302.972.97
241.293.753.75
261.373.923.92
218.100.860.86
143.140.370.37
141.170.450.45
203.241.331.33
136.200.840.84
324.383.663.66
249.301.461.46
213.661.861.86
387.480.720.72
475.364.434.43
389.461.351.35
372.553.813.81
222.242.852.85
252.272.862.86
229.26-0.59-0.59
239.311.311.31
331.874.884.88
386.534.664.66
420.324.534.53
500.632.592.59
379.502.892.89
406.483.743.74
334.783.293.29
310.784.634.63
211.180.020.02
234.202.782.78
468.544.904.90
212.230.620.62
308.380.530.53
347.22-1.86-1.86
303.834.194.19
260.382.852.85
295.381.531.53
160.221.231.23
299.35-0.18-0.18
608.694.174.17
199.16-1.10-1.10
327.473.373.37
284.752.612.61
586.208.958.95
612.633.633.63
505.464.184.18
189.211.161.16
369.473.463.46
230.263.043.04
378.324.454.45
243.22-2.56-2.56
276.213.213.21
381.695.805.80
219.241.461.46
306.245.185.18
142.16-0.91-0.91
158.16-1.94-1.94
194.15-2.08-2.08
319.253.933.93
317.233.843.84
318.343.203.20
311.411.771.77
246.31-0.28-0.28
361.833.553.55
404.493.803.80
621.934.634.63
263.793.963.96
435.44-1.17-1.17
546.59-1.30-1.30
292.381.701.70
220.281.371.37
292.141.761.76
416.655.705.70
279.341.811.81
289.555.145.14
381.453.773.77
211.22-0.50-0.50
278.403.923.92
470.616.336.33
218.260.540.54
244.320.800.80
292.24-2.07-2.07
218.261.471.47
475.585.315.31
290.793.403.40
368.525.115.11
314.372.962.96
204.31-0.29-0.29
588.561.341.34
1449.27
363.411.701.70
348.442.122.12
157.210.840.84
365.842.712.71
277.193.003.00
247.25-0.46-0.46
471.522.992.99
171.241.901.90
263.20-1.29-1.29
435.892.552.55
480.654.944.94
285.372.202.20
250.203.043.04
543.530.000.00
214.272.192.19
315.875.195.19
400.984.244.24
307.403.253.25
178.190.420.42
404.345.505.50
501.482.702.70
554.59-1.20-1.20
283.11-0.37-0.37
301.392.962.96
410.511.521.52
308.312.762.76
226.282.642.64
720.965.915.91
446.914.284.28
171.241.371.37
284.362.952.95
211.331.581.58
319.412.922.92
229.63-1.08-1.08
305.423.793.79
260.313.173.17
551.634.204.20
179.312.552.55
147.20-0.21-0.21
352.744.094.09
187.292.182.18
270.213.003.00
282.223.543.54
705.655.585.58
312.412.532.53
218.250.980.98
339.442.512.51
356.813.563.56
286.465.515.51
317.485.775.77
535.525.425.42
427.460.100.10
319.230.500.50
350.464.154.15
469.677.227.22
300.753.373.37
354.454.614.61
139.150.400.40
337.381.641.64
322.484.634.63
214.23-0.25-0.25
366.554.834.83
244.383.153.15
610.676.326.32
440.464.034.03
514.637.267.26
266.344.604.60
340.472.932.93
277.505.305.30
261.091.881.88
200.283.183.18
301.392.812.81
384.442.122.12
434.472.252.25
339.39-0.24-0.24
219.28-1.45-1.45
356.513.623.62
307.392.572.57
248.311.681.68
131.180.590.59
432.604.194.19
328.431.171.17
307.424.954.95
338.770.920.92
159.231.081.08
418.574.594.59
287.362.352.35
345.442.582.58
268.741.401.40
228.293.373.37
287.453.943.94
418.975.785.78
427.534.114.11
129.160.360.36
365.410.020.02
302.373.573.57
411.573.493.49
343.473.493.49
246.352.732.73
238.240.960.96
204.231.301.30
289.362.032.03
179.220.720.72
491.635.755.75
288.443.903.90
311.473.963.96
217.271.771.77
225.160.970.97
351.843.333.33
212.252.982.98
500.438.648.64
432.503.413.41
294.362.412.41
334.422.302.30
448.394.864.86
180.17-1.04-1.04
118.16-0.22-0.22
413.565.735.73
405.450.880.88
309.494.404.40
296.20-0.80-0.80
326.445.175.17
337.464.504.50
291.444.714.71
424.532.442.44
327.343.053.05
462.51-0.23-0.23
348.432.532.53
373.883.333.33
384.25
704.874.214.21
429.564.044.04
332.35-2.93-2.93
153.140.670.67
367.882.092.09
317.433.243.24
287.361.921.92
261.714.094.09
270.341.231.23
220.322.322.32
294.392.562.56
339.420.700.70
308.422.952.95
193.252.232.23
262.220.840.84
378.410.490.49
301.734.344.34
247.280.530.53
397.766.526.52
388.821.571.57
348.454.024.02
192.262.512.51
256.102.012.01
188.221.891.89
255.372.652.65
390.390.450.45
392.503.413.41
415.574.114.11
412.536.686.68
372.813.143.14
452.605.225.22
317.222.452.45
240.312.822.82
170.21-0.13-0.13
378.113.193.19
346.855.045.04
380.471.351.35
473.417.497.49
380.494.474.47
411.796.646.64
531.444.214.21
363.803.293.29
315.484.274.27
362.412.422.42
679.78-2.40-2.40
82.110.720.72
290.362.042.04
163.20-0.49-0.49
273.724.164.16
279.382.982.98
221.301.051.05
273.242.552.55
272.393.263.26
767.911.521.52
280.324.254.25
464.835.555.55
433.353.723.72
199.321.561.56
195.692.592.59
416.473.093.09
606.788.688.68
349.410.320.32
510.835.455.45
929.168.078.07
572.886.116.11
344.412.222.22
405.460.330.33
281.444.994.99
415.833.473.47
169.571.771.77
373.462.072.07
363.503.313.31
384.432.602.60
307.392.772.77
260.313.173.17
206.283.073.07
360.382.312.31
314.475.855.85
413.432.882.88
399.635.045.04
387.483.743.74
286.341.091.09
484.50-7.29-7.29
416.584.854.85
435.892.522.52
211.271.801.80
994.21-3.04-3.04
585.61-8.42-8.42
303.361.871.87
700.794.574.57
581.58-8.16-8.16
527.531.031.03
307.292.232.23
527.643.523.52
427.552.312.31
266.341.121.12
323.421.631.63
207.272.442.44
563.630.750.75
315.421.161.16
488.023.313.31
407.322.022.02
461.565.865.86
230.681.681.68
418.452.972.97
255.23-1.97-1.97
454.52-0.64-0.64
424.39-0.54-0.54
453.882.692.69
480.57-1.28-1.28
602.687.337.33
169.180.090.09
332.31-3.58-3.58
585.660.510.51
444.44-0.21-0.21
166.251.281.28
458.501.981.98
828.013.013.01
424.095.465.46
315.684.074.07
406.55-0.86-0.86
327.123.863.86
366.845.515.51
135.13-0.11-0.11
202.641.071.07
211.221.621.62
204.302.152.15
210.280.070.07
433.502.522.52
259.22-2.70-2.70
369.491.291.29
237.732.902.90
236.23-0.21-0.21
129.09-0.51-0.51
308.333.613.61
353.333.523.52
336.302.902.90
459.512.702.70
179.20-0.78-0.78
534.434.954.95
753.942.732.73
228.253.463.46
392.584.484.48
318.301.741.74
419.534.914.91
496.633.903.90
161.220.180.18
265.343.243.24
198.18-1.03-1.03
244.21-3.17-3.17
351.374.084.08
611.746.486.48
344.462.732.73
481.552.402.40
212.250.940.94
342.30-5.40-5.40
335.472.202.20
324.403.813.81
434.502.272.27
442.42-0.44-0.44
170.241.381.38
530.663.013.01
305.342.642.64
302.282.522.52
248.311.961.96
391.296.116.11
293.734.164.16
246.351.771.77
289.740.880.88
339.353.653.65
335.883.783.78
387.53-1.31-1.31
461.500.090.09
453.46-0.54-0.54
391.565.975.97
392.584.484.48
645.61-8.56-8.56
492.534.284.28
594.67-0.59-0.59
315.412.972.97
366.482.172.17
300.403.593.59
789.10-0.03-0.03
167.211.421.42
455.554.404.40
268.27-1.18-1.18
417.511.601.60
465.531.301.30
367.452.232.23
324.402.212.21
464.860.260.26
220.313.463.46
570.776.836.83
394.462.732.73
295.854.174.17
257.260.810.81
423.470.480.48
542.58-0.92-0.92
349.410.350.35
410.43-0.05-0.05
253.353.243.24
575.63-1.40-1.40
460.512.432.43
470.463.633.63
420.51-1.60-1.60
309.410.630.63
785.896.166.16
285.69-0.30-0.30
441.40-0.04-0.04
317.392.282.28
776.874.564.56
343.905.105.10
434.472.352.35
551.773.293.29
244.21-3.01-3.01
371.392.582.58
435.481.271.27
250.301.641.64
537.584.644.64
267.28-4.49-4.49
344.31-5.76-5.76
536.8912.9412.94
634.734.574.57
427.46-0.54-0.54
645.68-1.11-1.11
473.45-0.73-0.73
421.421.631.63
116.07-0.29-0.29
186.241.561.56
385.382.462.46
539.643.623.62
388.423.203.20
455.47-0.62-0.62
813.983.623.62
627.755.815.81
289.163.593.59
289.301.151.15
747.962.442.44
420.635.115.11
303.360.920.92
303.68-0.35-0.35
780.952.222.22
378.523.173.17
138.06-0.09-0.09
225.291.521.52
331.300.010.01
321.833.673.67
398.421.391.39
359.350.760.76
450.355.045.04
386.452.382.38
143.231.541.54
414.344.874.87
367.493.993.99
274.413.513.51
365.21-1.72-1.72
370.851.841.84
414.503.123.12
450.934.114.11
464.443.993.99
227.742.762.76
1139.76
532.574.464.46
485.954.394.39
270.762.422.42
328.451.671.67
412.646.076.07
477.564.264.26
282.453.523.52
334.576.066.06
296.412.662.66
486.444.614.61
243.173.053.05
341.430.280.28
404.423.073.07
387.725.865.86
578.664.164.16
284.362.212.21
424.625.125.12
412.615.095.09
273.741.621.62
380.875.875.87
183.251.131.13
224.260.960.96
329.443.473.47
528.546.586.58
398.342.462.46
431.952.242.24
451.623.193.19
241.240.530.53
228.21-2.14-2.14
231.251.421.42
228.220.180.18
307.444.424.42
612.650.330.33
340.494.834.83
239.311.911.91
557.845.975.97
613.913.123.12
511.57-0.87-0.87
353.534.114.11
529.794.414.41
404.512.422.42
177.250.980.98
474.552.222.22
433.046.546.54
357.426.146.14
319.253.933.93
314.261.741.74
181.21-0.60-0.60
382.535.315.31
753.008.718.71
1322.50
289.813.533.53
354.37-1.44-1.44
167.210.770.77
111.15-0.09-0.09
291.392.182.18
278.424.364.36
357.322.712.71
274.803.823.82
382.544.264.26
421.474.524.52
238.200.700.70
215.291.421.42
322.504.394.39
349.394.444.44
837.062.212.21
477.425.185.18
193.200.890.89
356.230.400.40
492.694.264.26
527.570.470.47
390.523.583.58
216.282.142.14
572.565.715.71
1058.05
185.232.152.15
376.422.352.35
321.164.094.09
582.664.694.69
429.605.415.41
515.54-2.49-2.49
236.310.160.16
436.964.194.19
454.875.645.64
342.864.204.20
386.484.644.64
420.851.491.49
242.240.090.09
289.371.931.93
312.763.823.82
298.351.531.53
308.252.242.24
603.752.832.83
221.302.742.74
325.844.334.33
177.462.132.13
450.535.745.74
465.571.741.74
255.792.832.83
276.383.483.48
244.27-0.75-0.75
218.270.490.49
266.26-1.19-1.19
447.472.562.56
294.351.191.19
257.22-1.45-1.45
416.136.456.45
328.443.773.77
349.821.521.52
400.656.596.59
345.851.901.90
466.41-2.88-2.88
354.473.093.09
279.342.892.89
455.417.307.30
556.661.321.32
203.24-1.24-1.24
249.31-0.05-0.05
288.393.053.05
392.881.901.90
141.262.342.34
365.483.343.34
145.541.151.15
482.634.774.77
431.562.662.66
298.363.763.76
295.343.433.43
264.321.891.89
440.514.224.22
193.201.271.27
392.523.773.77
468.596.206.20
259.393.553.55
248.202.002.00
482.825.695.69
291.693.483.48
330.516.476.47
1346.38
385.492.982.98
563.586.326.32
406.501.711.71
308.124.504.50
546.944.514.51
452.414.754.75
602.64-0.45-0.45
380.514.154.15
231.291.621.62
395.383.333.33
286.283.003.00
284.36-2.67-2.67
383.470.730.73
326.441.551.55
574.994.994.99
501.515.545.54
283.312.752.75
522.57-3.16-3.16
283.330.760.76
565.805.625.62
386.493.303.30
313.340.950.95
412.884.514.51
527.533.853.85
345.874.524.52
238.333.273.27
379.503.863.86
246.311.811.81
144.13-0.11-0.11
346.385.005.00
374.372.532.53
380.533.893.89
358.442.572.57
339.33-0.80-0.80
469.955.165.16
1227.40
426.591.571.57
415.433.753.75
505.574.214.21
395.572.142.14
713.1414.5714.57
372.556.266.26
411.474.634.63
584.681.001.00
398.687.727.72
416.874.484.48
868.468.668.66
331.471.321.32
203.282.922.92
466.462.632.63
285.774.264.26
441.233.013.01
406.422.802.80
506.614.944.94
540.023.913.91
389.430.710.71
666.915.485.48
499.624.514.51
572.754.734.73
520.503.403.40
490.442.352.35
443.313.393.39
446.564.184.18
239.363.753.75
217.22-1.83-1.83
280.411.651.65
499.435.015.01
509.642.022.02
434.534.604.60
398.503.583.58