Basic Information
ID: ALA5303714
Type: Functional
Description: Inhibition of SARS-CoV-2 3CL-Pro proteolytic cleavage of a dual-labeled substrate by FRET at 1mM DTT.
Organism: Severe acute respiratory syndrome coronavirus 2
Activity Charts
Bioactivity
Activity Types for Assay ALA5303714
IC50 relative
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 270.24 | 2.58 | 2.58 |
| 302.37 | 3.57 | 3.57 |
| 369.37 | 3.52 | 3.52 |
| 172.18 | 2.01 | 2.01 |
| 222.27 | 0.66 | 0.66 |
| 209.30 | 2.57 | 2.57 |
| 227.29 | 3.05 | 3.05 |
| 231.66 | 1.03 | 1.03 |
| 149.22 | 2.29 | 2.29 |
| 351.86 | 2.69 | 2.69 |
| 475.63 | 3.59 | 3.59 |
| 318.24 | 1.69 | 1.69 |
| 220.18 | 1.02 | 1.02 |
| 154.60 | 2.11 | 2.11 |
| 171.27 | 1.54 | 1.54 |
| 213.19 | -0.24 | -0.24 |
| 299.31 | -1.69 | -1.69 |
| 296.37 | 3.44 | 3.44 |
| 245.88 | 2.52 | 2.52 |
| 519.69 | 1.71 | 1.71 |
| 178.22 | 0.95 | 0.95 |
| 353.20 | 2.18 | 2.18 |
| 428.49 | 5.68 | 5.68 |
| 345.42 | 2.90 | 2.90 |
| 436.32 | 3.42 | 3.42 |
| 257.26 | 0.81 | 0.81 |
| 332.50 | 5.71 | 5.71 |
| 290.26 | 1.92 | 1.92 |
| 291.78 | 2.38 | 2.38 |
| 261.35 | 3.48 | 3.48 |
| 306.32 | 1.89 | 1.89 |
| 960.82 | 6.67 | 6.67 |
| 182.22 | -0.25 | -0.25 |
| 505.51 | 4.84 | 4.84 |
| 293.71 | -1.76 | -1.76 |
| 374.65 | 2.56 | 2.56 |
| 361.61 | 2.65 | 2.65 |
| 472.69 | 5.21 | 5.21 |
| 241.32 | 3.36 | 3.36 |
| 334.42 | 2.30 | 2.30 |
| 127.17 | 0.61 | 0.61 |
| 296.39 | 3.15 | 3.15 |
| 415.49 | 5.25 | 5.25 |
| 231.28 | 2.41 | 2.41 |
| 415.46 | 4.69 | 4.69 |
| 346.77 | 3.32 | 3.32 |
| 180.23 | 1.86 | 1.86 |
| 359.43 | 3.05 | 3.05 |
| 302.36 | 1.85 | 1.85 |
| 362.48 | 3.08 | 3.08 |
| 273.33 | 3.81 | 3.81 |
| 316.36 | 2.56 | 2.56 |
| 212.66 | 2.68 | 2.68 |
| 1017.64 | 9.00 | 9.00 |
| 497.92 | 5.71 | 5.71 |
| 260.30 | 3.53 | 3.53 |
| 380.47 | 3.47 | 3.47 |
| 658.83 | 7.59 | 7.59 |
| 381.35 | 3.56 | 3.56 |
| 668.67 | 0.01 | 0.01 |
| 375.46 | 4.57 | 4.57 |
| 233.10 | 1.52 | 1.52 |
| 473.44 | 2.45 | 2.45 |
| 406.37 | 2.88 | 2.88 |