Basic Information
ID: ALA615420
Type: Binding
Description: Ability of compound to inhibit the activity of 3-hydroxy-3-methylglutarylcoenzyme A(HMGR) reductase in rat liver microsomes
Format: BAO_0000251
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsome
Target: HMG-CoA reductase(ALA3247)
Document: ALA1124675
Ability of compound to inhibit the activity of 3-hydroxy-3-methylglutarylcoenzyme A(HMGR) reductase in rat liver microsomes: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA615420
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 422.56 | 4.00 | 4.00 |
| 350.41 | 2.50 | 2.50 |
| 408.54 | 3.47 | 3.47 |
| 424.58 | 3.80 | 3.80 |
| 238.28 | 1.21 | 1.21 |
| 406.52 | 3.68 | 3.68 |
| 236.27 | 1.41 | 1.41 |