Basic Information
ID: ALA615820
Type: Binding
Description: Binding affinity against 5-hydroxytryptamine 1A receptor (5-HT1A) by displacement of [3H]8-OH-DPAT from rat hippocampus membranes
Tissue: Hippocampus
Subcellular Fraction: Membrane
Activity Charts
Bioactivity
Activity Types for Assay ALA615820
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 329.37 | 3.33 | 3.33 |
| 313.40 | 3.19 | 3.19 |
| 277.41 | 3.04 | 3.04 |
| 265.36 | 2.48 | 2.48 |
| 284.75 | 2.61 | 2.61 |
| 271.36 | 3.42 | 3.42 |
| 462.52 | 6.12 | 6.12 |
| 357.50 | 5.56 | 5.56 |
| 480.51 | 6.26 | 6.26 |
| 411.47 | 6.27 | 6.27 |
| 450.53 | 5.93 | 5.93 |
| 354.25 | 5.25 | 5.25 |
| 310.37 | 3.82 | 3.82 |
| 309.33 | 4.44 | 4.44 |
| 303.35 | 4.08 | 4.08 |
| 315.39 | 3.95 | 3.95 |
| 299.39 | 4.25 | 4.25 |
| 312.37 | 3.71 | 3.71 |
| 389.50 | 4.97 | 4.97 |
| 497.59 | 6.65 | 6.65 |
| 443.47 | 5.69 | 5.69 |
| 393.46 | 4.81 | 4.81 |
| 417.55 | 5.58 | 5.58 |
| 437.97 | 5.93 | 5.93 |
| 471.52 | 6.29 | 6.29 |
| 377.92 | 5.91 | 5.91 |
| 421.51 | 5.41 | 5.41 |
| 353.36 | 4.96 | 4.96 |
| 319.81 | 4.60 | 4.60 |
| 346.27 | 4.57 | 4.57 |
| 393.27 | 4.41 | 4.41 |
| 315.39 | 3.95 | 3.95 |
| 285.36 | 3.95 | 3.95 |
| 326.83 | 4.33 | 4.33 |
| 317.43 | 4.96 | 4.96 |
| 315.84 | 4.77 | 4.77 |
| 315.84 | 4.77 | 4.77 |
| 301.36 | 3.65 | 3.65 |
| 301.36 | 3.65 | 3.65 |
| 286.35 | 4.37 | 4.37 |
| 270.35 | 5.14 | 5.14 |
| 336.26 | 5.11 | 5.11 |
| 301.36 | 3.65 | 3.65 |
| 299.39 | 4.25 | 4.25 |
| 315.39 | 3.95 | 3.95 |
| 310.37 | 3.82 | 3.82 |
| 303.35 | 4.08 | 4.08 |
| 319.81 | 4.60 | 4.60 |
| 301.82 | 4.46 | 4.46 |
| 292.38 | 3.68 | 3.68 |
| 285.36 | 3.95 | 3.95 |
| 303.35 | 4.08 | 4.08 |
| 299.39 | 4.25 | 4.25 |
| 299.39 | 4.29 | 4.29 |
| 361.46 | 5.39 | 5.39 |
| 285.36 | 3.95 | 3.95 |
| 409.91 | 5.32 | 5.32 |
| 343.47 | 5.47 | 5.47 |
| 393.27 | 4.41 | 4.41 |
| 335.37 | 4.83 | 4.83 |
| 357.43 | 4.21 | 4.21 |
| 311.43 | 4.21 | 4.21 |
| 303.35 | 4.08 | 4.08 |
| 301.82 | 4.46 | 4.46 |
| 346.27 | 4.57 | 4.57 |
| 299.39 | 4.34 | 4.34 |
| 324.40 | 4.21 | 4.21 |
| 317.38 | 4.47 | 4.47 |
| 303.35 | 4.08 | 4.08 |
| 335.37 | 4.83 | 4.83 |
| 285.36 | 3.95 | 3.95 |
| 301.82 | 4.46 | 4.46 |
| 343.47 | 5.47 | 5.47 |
| 303.35 | 4.08 | 4.08 |
| 327.40 | 4.20 | 4.20 |
| 335.42 | 5.10 | 5.10 |
| 329.37 | 3.67 | 3.67 |
| 292.38 | 3.68 | 3.68 |
| 267.37 | 3.81 | 3.81 |
| 335.37 | 4.83 | 4.83 |