Basic Information
ID: ALA616344
Type: Binding
Description: Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacement
Format: BAO_0000019
Target: Serotonin 1a (5-HT1a) receptor(ALA273)
Document: ALA1129278
Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacement: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA616344
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 249.35 | 2.15 | 2.15 |
| 209.29 | 1.42 | 1.42 |
| 190.25 | 1.68 | 1.68 |
| 218.30 | 2.28 | 2.28 |
| 247.38 | 3.37 | 3.37 |
| 192.26 | 1.10 | 1.10 |
| 162.24 | 1.10 | 1.10 |
| 316.43 | 0.50 | 0.50 |
| 248.33 | 1.91 | 1.91 |
| 261.41 | 3.67 | 3.67 |
| 204.27 | 1.98 | 1.98 |
| 190.25 | 1.76 | 1.76 |
| 176.22 | 1.37 | 1.37 |
| 212.30 | 2.25 | 2.25 |
| 176.22 | 1.37 | 1.37 |
| 371.87 | 2.36 | 2.36 |
| 228.29 | 1.96 | 1.96 |
| 412.49 | 2.94 | 2.94 |
| 330.47 | 3.55 | 3.55 |
| 291.19 | 3.65 | 3.65 |
| 216.26 | 2.68 | 2.68 |
| 257.29 | 2.80 | 2.80 |
| 306.38 | 4.69 | 4.69 |
| 318.42 | 4.47 | 4.47 |
| 270.33 | 2.81 | 2.81 |
| 268.40 | 3.76 | 3.76 |
| 298.43 | 4.14 | 4.14 |
| 266.82 | 3.65 | 3.65 |
| 364.45 | 2.28 | 2.28 |
| 277.17 | 3.31 | 3.31 |
| 470.65 | 4.98 | 4.98 |
| 281.40 | 3.38 | 3.38 |
| 290.39 | 2.29 | 2.29 |
| 225.29 | 1.00 | 1.00 |
| 244.34 | 2.96 | 2.96 |
| 248.33 | 1.60 | 1.60 |
| 281.40 | 3.68 | 3.68 |
| 275.39 | 3.36 | 3.36 |
| 414.55 | 3.42 | 3.42 |
| 306.41 | 1.85 | 1.85 |
| 320.32 | 2.92 | 2.92 |
| 238.76 | 2.87 | 2.87 |
| 350.42 | 2.44 | 2.44 |
| 363.46 | 2.89 | 2.89 |
| 333.43 | 1.64 | 1.64 |
| 367.49 | 3.03 | 3.03 |
| 408.50 | 3.40 | 3.40 |
| 316.45 | 3.16 | 3.16 |
| 216.28 | 1.99 | 1.99 |
| 210.71 | 2.09 | 2.09 |
| 379.46 | 2.50 | 2.50 |
| 407.51 | 3.28 | 3.28 |
| 258.39 | 3.61 | 3.61 |
| 412.57 | 4.19 | 4.19 |
| 242.32 | 2.26 | 2.26 |
| 256.35 | 3.20 | 3.20 |
| 270.38 | 3.68 | 3.68 |
| 371.49 | 1.70 | 1.70 |
| 423.51 | 2.90 | 2.90 |
| 265.36 | 3.54 | 3.54 |
| 358.44 | 2.41 | 2.41 |
| 310.44 | 3.45 | 3.45 |
| 315.50 | 5.04 | 5.04 |
| 269.35 | 2.85 | 2.85 |
| 233.36 | 1.55 | 1.55 |
| 335.41 | 2.10 | 2.10 |
| 314.82 | 3.23 | 3.23 |
| 232.71 | 3.20 | 3.20 |
| 214.27 | 2.25 | 2.25 |
| 273.42 | 3.87 | 3.87 |
| 289.38 | 3.95 | 3.95 |
| 379.50 | 2.89 | 2.89 |
| 273.34 | 1.78 | 1.78 |
| 252.75 | 2.40 | 2.40 |
| 226.32 | 3.20 | 3.20 |
| 446.61 | 3.78 | 3.78 |
| 224.74 | 2.48 | 2.48 |
| 332.49 | 3.94 | 3.94 |
| 373.54 | 3.29 | 3.29 |
| 377.43 | 3.67 | 3.67 |
| 265.40 | 3.77 | 3.77 |
| 255.41 | 3.65 | 3.65 |
| 288.39 | 4.46 | 4.46 |
| 302.42 | 4.41 | 4.41 |
| 347.50 | 2.90 | 2.90 |
| 365.41 | 0.95 | 0.95 |
| 426.48 | 3.15 | 3.15 |
| 289.38 | 3.95 | 3.95 |
| 324.47 | 3.84 | 3.84 |
| 406.48 | 3.74 | 3.74 |
| 275.40 | 1.72 | 1.72 |
| 309.45 | 4.17 | 4.17 |
| 233.35 | 3.11 | 3.11 |
| 284.36 | 3.06 | 3.06 |
| 164.21 | -0.11 | -0.11 |
| 408.46 | 2.79 | 2.79 |
| 425.62 | 3.93 | 3.93 |
| 286.81 | 3.66 | 3.66 |
| 297.40 | 3.63 | 3.63 |
| 309.41 | 0.63 | 0.63 |