Basic Information
ID: ALA617720
Type: Functional
Description: 5-hydroxytryptamine 3 receptor antagonistic activity measured by inhibition of 5-HT-induced bradycardia (iv administration 10 ug/kg dose in urethane-anesthetized rats)
Format: BAO_0000218
Target: Serotonin 3 (5-HT3) receptor(ALA2094116)
Document: ALA1125286
5-hydroxytryptamine 3 receptor antagonistic activity measured by inhibition of 5-HT-induced bradycardia (iv administration 10 ug/kg dose in urethane-anesthetized rats): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA617720
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 284.36 | 2.95 | 2.95 |
| 299.37 | 3.52 | 3.52 |
| 330.43 | 2.37 | 2.37 |
| 328.46 | 3.06 | 3.06 |
| 393.33 | 3.52 | 3.52 |
| 332.42 | 2.89 | 2.89 |
| 315.41 | 3.18 | 3.18 |
| 315.41 | 3.10 | 3.10 |
| 314.43 | 2.76 | 2.76 |
| 301.39 | 2.71 | 2.71 |
| 287.36 | 2.40 | 2.40 |
| 299.37 | 3.52 | 3.52 |
| 348.87 | 3.41 | 3.41 |
| 348.87 | 3.41 | 3.41 |
| 334.85 | 3.02 | 3.02 |
| 314.43 | 2.76 | 2.76 |
| 300.40 | 2.37 | 2.37 |
| 335.40 | 4.37 | 4.37 |
| 301.39 | 2.79 | 2.79 |
| 330.43 | 2.46 | 2.46 |
| 344.46 | 2.76 | 2.76 |
| 314.43 | 2.76 | 2.76 |
| 314.43 | 2.76 | 2.76 |
| 335.83 | 3.45 | 3.45 |
| 319.38 | 2.93 | 2.93 |
| 331.41 | 2.80 | 2.80 |
| 315.41 | 3.35 | 3.35 |
| 314.21 | 3.78 | 3.78 |
| 348.87 | 3.41 | 3.41 |
| 349.86 | 3.84 | 3.84 |