Basic Information
ID: ALA618436
Type: Functional
Description: In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.
Activity Charts
Bioactivity
Activity Types for Assay ALA618436
Kd
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 293.37 | 3.13 | 3.13 |
| 309.80 | 1.75 | 1.75 |
| 473.53 | 2.54 | 2.54 |
| 394.38 | 1.66 | 1.66 |
| 331.20 | 2.95 | 2.95 |
| 409.41 | 1.36 | 1.36 |
| 419.43 | 1.23 | 1.23 |
| 449.46 | 1.24 | 1.24 |
| 435.48 | 2.54 | 2.54 |
| 447.49 | 2.15 | 2.15 |
| 362.39 | 1.67 | 1.67 |
| 436.46 | 2.19 | 2.19 |
| 463.53 | 3.18 | 3.18 |
| 475.54 | 2.79 | 2.79 |
| 419.43 | 1.23 | 1.23 |
| 403.44 | 1.53 | 1.53 |
| 503.62 | 2.15 | 2.15 |
| 407.42 | 1.76 | 1.76 |
| 461.52 | 2.54 | 2.54 |
| 409.96 | 3.32 | 3.32 |
| 395.93 | 2.93 | 2.93 |
| 368.87 | 1.34 | 1.34 |
| 403.31 | 2.00 | 2.00 |
| 339.82 | 1.46 | 1.46 |
| 353.85 | 1.76 | 1.76 |
| 378.69 | 2.53 | 2.53 |
| 388.30 | 2.41 | 2.41 |
| 314.21 | 3.78 | 3.78 |
| 419.43 | 1.23 | 1.23 |
| 419.43 | 1.23 | 1.23 |