Basic Information
ID: ALA619256
Type: Binding
Description: Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).
Activity Charts
Bioactivity
Activity Types for Assay ALA619256
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 302.37 | 3.57 | 3.57 |
| 338.74 | 3.36 | 3.36 |
| 226.23 | 2.23 | 2.23 |
| 374.39 | 3.59 | 3.59 |
| 346.34 | 3.64 | 3.64 |
| 356.38 | 4.06 | 4.06 |
| 401.37 | 3.96 | 3.96 |
| 386.40 | 4.07 | 4.07 |
| 376.36 | 3.00 | 3.00 |
| 392.36 | 2.70 | 2.70 |
| 662.74 | 8.32 | 8.32 |
| 359.34 | 4.14 | 4.14 |
| 362.34 | 3.35 | 3.35 |
| 358.39 | 3.98 | 3.98 |
| 448.47 | 4.00 | 4.00 |
| 418.45 | 3.99 | 3.99 |
| 296.32 | 3.14 | 3.14 |
| 330.34 | 3.94 | 3.94 |
| 360.37 | 3.29 | 3.29 |
| 386.45 | 4.76 | 4.76 |
| 342.39 | 4.71 | 4.71 |
| 472.58 | 5.89 | 5.89 |
| 344.37 | 3.59 | 3.59 |
| 389.36 | 3.49 | 3.49 |
| 450.49 | 5.16 | 5.16 |
| 388.42 | 3.98 | 3.98 |
| 374.39 | 3.68 | 3.68 |
| 372.42 | 4.37 | 4.37 |
| 464.52 | 5.56 | 5.56 |