Basic Information
ID: ALA620594
Type: Functional
Description: Antagonistic activity evaluated by ability to block serotonin induced relaxation (mediated by activation of 5-hydroxytryptamine 4 receptor) in carbamylcholine (10e-6 M) contracted esophagus at a concentration of 10e-5 M.
Format: BAO_0000221
Organism: Rattus norvegicus
Tissue: Esophagus
Target: Serotonin 4 (5-HT4) receptor(ALA4317)
Document: ALA1131384
Antagonistic activity evaluated by ability to block serotonin induced relaxation (mediated by activation of 5-hydroxytryptamine 4 receptor) in carbamylcholine (10e-6 M) contracted esophagus at a concentration of 10e-5 M.: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA620594
Relaxation
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.42 | 2.32 | 2.32 |
| 284.36 | 1.92 | 1.92 |
| 284.36 | 2.95 | 2.95 |
| 323.82 | 2.29 | 2.29 |
| 294.40 | 3.19 | 3.19 |
| 314.43 | 2.83 | 2.83 |
| 465.95 | 3.36 | 3.36 |
| 348.87 | 3.41 | 3.41 |