Basic Information
ID: ALA639302
Type: Binding
Description: In vitro Acyl coenzyme A:cholesterol acyltransferase inhibitory activity (IAI) was determined by measuring the incorporation of [1-14C]oleolyl-CoA into cholesterol esters by intestinal microsomes isolated from cholesterol-fed rabbits
Organism: Oryctolagus cuniculus
Tissue: Intestine
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA639302
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 433.63 | 8.08 | 8.08 |
| 377.53 | 6.52 | 6.52 |
| 431.53 | 6.95 | 6.95 |
| 517.80 | 10.42 | 10.42 |
| 489.74 | 9.64 | 9.64 |
| 447.66 | 8.47 | 8.47 |
| 473.75 | 8.81 | 8.81 |
| 362.51 | 6.16 | 6.16 |
| 430.55 | 6.98 | 6.98 |
| 487.77 | 9.20 | 9.20 |
| 363.50 | 6.13 | 6.13 |
| 461.69 | 8.86 | 8.86 |
| 319.45 | 4.52 | 4.52 |
| 433.63 | 8.08 | 8.08 |
| 475.71 | 9.20 | 9.20 |
| 475.71 | 9.25 | 9.25 |
| 435.67 | 8.41 | 8.41 |
| 419.61 | 7.69 | 7.69 |
| 405.58 | 7.30 | 7.30 |
| 461.69 | 8.72 | 8.72 |
| 345.49 | 5.63 | 5.63 |
| 427.55 | 6.92 | 6.92 |
| 465.77 | 9.51 | 9.51 |
| 477.76 | 9.57 | 9.57 |
| 375.56 | 6.08 | 6.08 |
| 430.55 | 6.52 | 6.52 |
| 390.57 | 6.94 | 6.94 |
| 317.43 | 4.27 | 4.27 |
| 399.56 | 6.51 | 6.51 |
| 349.47 | 5.74 | 5.74 |
| 357.48 | 5.93 | 5.93 |
| 394.54 | 4.21 | 4.21 |
| 405.95 | 6.73 | 6.73 |
| 371.50 | 6.08 | 6.08 |
| 441.64 | 8.18 | 8.18 |
| 489.74 | 9.64 | 9.64 |
| 561.64 | 9.64 | 9.64 |
| 391.55 | 6.91 | 6.91 |
| 383.49 | 5.79 | 5.79 |
| 423.60 | 7.53 | 7.53 |
| 413.51 | 6.89 | 6.89 |
| 395.55 | 6.09 | 6.09 |
| 415.54 | 7.01 | 7.01 |
| 429.56 | 7.36 | 7.36 |
| 405.58 | 7.30 | 7.30 |
| 461.69 | 8.86 | 8.86 |
| 467.60 | 6.64 | 6.64 |
| 443.59 | 6.88 | 6.88 |
| 429.56 | 6.55 | 6.55 |
| 445.59 | 7.48 | 7.48 |
| 404.60 | 7.33 | 7.33 |
| 407.56 | 6.05 | 6.05 |
| 481.68 | 8.16 | 8.16 |
| 413.47 | 5.07 | 5.07 |
| 355.43 | 5.36 | 5.36 |
| 391.47 | 6.37 | 6.37 |
| 341.41 | 5.22 | 5.22 |
| 425.57 | 7.47 | 7.47 |
| 313.35 | 4.21 | 4.21 |
| 488.76 | 9.67 | 9.67 |
| 363.50 | 6.13 | 6.13 |
| 416.52 | 6.98 | 6.98 |
| 385.53 | 6.12 | 6.12 |
| 361.46 | 5.67 | 5.67 |
| 474.73 | 9.28 | 9.28 |
| 460.70 | 8.89 | 8.89 |
| 432.65 | 8.11 | 8.11 |
| 432.65 | 8.11 | 8.11 |
| 424.59 | 7.50 | 7.50 |
| 421.65 | 8.02 | 8.02 |
| 363.52 | 6.21 | 6.21 |
| 449.70 | 8.79 | 8.79 |
| 455.62 | 6.57 | 6.57 |
| 449.70 | 8.80 | 8.80 |
| 393.59 | 7.24 | 7.24 |
| 363.50 | 6.13 | 6.13 |
| 363.50 | 6.13 | 6.13 |