Basic Information
ID: ALA640700
Type: Binding
Description: Binding affinity towards the adenosine A1 receptor in cerebral cortices of Sprague-Dawley male rats using [3H]CHA as radioligand.
Activity Charts
Bioactivity
Activity Types for Assay ALA640700
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 227.27 | 2.10 | 2.10 |
| 241.30 | 2.12 | 2.12 |
| 255.32 | 2.66 | 2.66 |
| 275.35 | 2.62 | 2.62 |
| 222.25 | 0.08 | 0.08 |
| 194.19 | -1.03 | -1.03 |
| 285.69 | 2.77 | 2.77 |
| 349.39 | 0.18 | 0.18 |
| 297.32 | 1.74 | 1.74 |
| 365.87 | 4.54 | 4.54 |
| 263.25 | 2.38 | 2.38 |
| 245.26 | 2.24 | 2.24 |
| 289.73 | 2.45 | 2.45 |
| 245.26 | 2.24 | 2.24 |
| 324.17 | 3.11 | 3.11 |
| 280.35 | 3.94 | 3.94 |
| 261.26 | 1.94 | 1.94 |
| 337.81 | 4.42 | 4.42 |
| 295.73 | 3.18 | 3.18 |
| 289.77 | 3.09 | 3.09 |
| 255.32 | 2.43 | 2.43 |
| 275.74 | 3.06 | 3.06 |
| 241.30 | 2.41 | 2.41 |
| 379.72 | 4.41 | 4.41 |
| 343.74 | 3.80 | 3.80 |
| 233.66 | 1.82 | 1.82 |
| 259.29 | 2.26 | 2.26 |
| 295.27 | 3.12 | 3.12 |
| 299.23 | 2.87 | 2.87 |
| 219.63 | 1.51 | 1.51 |
| 313.21 | 2.39 | 2.39 |
| 203.18 | 1.00 | 1.00 |
| 281.36 | 2.83 | 2.83 |
| 203.18 | 1.00 | 1.00 |
| 329.67 | 2.91 | 2.91 |
| 267.34 | 2.44 | 2.44 |
| 283.33 | 1.68 | 1.68 |
| 261.72 | 2.75 | 2.75 |
| 249.22 | 1.99 | 1.99 |
| 287.63 | 2.53 | 2.53 |
| 283.38 | 3.25 | 3.25 |
| 255.32 | 2.83 | 2.83 |
| 185.19 | 0.86 | 0.86 |
| 338.24 | 3.99 | 3.99 |
| 303.80 | 3.34 | 3.34 |
| 219.63 | 1.51 | 1.51 |
| 231.23 | 1.85 | 1.85 |
| 231.23 | 1.85 | 1.85 |
| 365.87 | 4.54 | 4.54 |
| 329.84 | 4.24 | 4.24 |
| 253.31 | 2.27 | 2.27 |
| 213.24 | 1.71 | 1.71 |
| 199.22 | 1.32 | 1.32 |
| 269.35 | 2.69 | 2.69 |
| 323.79 | 4.24 | 4.24 |
| 315.81 | 3.85 | 3.85 |
| 257.30 | 1.24 | 1.24 |
| 254.30 | 0.69 | 0.69 |
| 268.32 | 1.03 | 1.03 |
| 291.31 | 2.94 | 2.94 |
| 273.31 | 2.80 | 2.80 |
| 243.27 | 1.43 | 1.43 |
| 296.16 | 3.40 | 3.40 |
| 273.31 | 2.80 | 2.80 |
| 324.22 | 3.97 | 3.97 |
| 289.77 | 3.31 | 3.31 |
| 231.23 | 1.56 | 1.56 |
| 247.69 | 2.08 | 2.08 |
| 239.28 | 1.88 | 1.88 |
| 269.35 | 2.90 | 2.90 |
| 241.30 | 2.49 | 2.49 |
| 227.27 | 1.88 | 1.88 |
| 219.18 | 0.70 | 0.70 |
| 275.29 | 2.25 | 2.25 |
| 247.69 | 2.08 | 2.08 |
| 213.24 | 1.42 | 1.42 |
| 253.31 | 2.19 | 2.19 |
| 282.13 | 2.73 | 2.73 |
| 213.24 | 1.34 | 1.34 |
| 253.26 | 1.40 | 1.40 |
| 353.32 | 4.18 | 4.18 |
| 369.78 | 4.69 | 4.69 |
| 355.75 | 4.30 | 4.30 |
| 215.22 | 0.87 | 0.87 |
| 271.18 | 2.02 | 2.02 |
| 313.26 | 3.26 | 3.26 |
| 329.71 | 3.77 | 3.77 |
| 241.30 | 2.27 | 2.27 |
| 277.28 | 2.40 | 2.40 |
| 289.77 | 3.31 | 3.31 |
| 271.32 | 2.28 | 2.28 |
| 259.29 | 2.41 | 2.41 |
| 308.30 | -1.84 | -1.84 |