Basic Information
ID: ALA641353
Type: Binding
Description: Inhibition of aldose reductase (aldo-keto reductase, AKR1B1) isolated from human placenta.
Format: BAO_0000019
Target: Aldose reductase(ALA1900)
Document: ALA1125712
Inhibition of aldose reductase (aldo-keto reductase, AKR1B1) isolated from human placenta.: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA641353
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 391.20 | 2.97 | 2.97 |
| 419.38 | 3.70 | 3.70 |
| 352.38 | 2.08 | 2.08 |
| 411.44 | 2.70 | 2.70 |
| 381.41 | 2.69 | 2.69 |
| 420.28 | 3.99 | 3.99 |
| 381.41 | 2.69 | 2.69 |
| 487.38 | 4.72 | 4.72 |
| 381.41 | 2.69 | 2.69 |
| 453.83 | 4.35 | 4.35 |
| 437.37 | 3.84 | 3.84 |
| 381.41 | 2.69 | 2.69 |
| 365.41 | 2.99 | 2.99 |
| 365.41 | 2.99 | 2.99 |
| 415.47 | 4.14 | 4.14 |
| 435.89 | 4.49 | 4.49 |
| 420.28 | 3.99 | 3.99 |
| 387.37 | 2.96 | 2.96 |
| 420.28 | 3.99 | 3.99 |
| 329.31 | 2.02 | 2.02 |
| 384.85 | 3.00 | 3.00 |
| 365.41 | 2.99 | 2.99 |
| 430.28 | 3.44 | 3.44 |
| 385.83 | 3.34 | 3.34 |
| 387.37 | 2.96 | 2.96 |
| 419.38 | 3.70 | 3.70 |
| 430.28 | 3.44 | 3.44 |
| 419.38 | 3.70 | 3.70 |
| 383.45 | 3.38 | 3.38 |
| 419.38 | 3.70 | 3.70 |
| 433.41 | 3.89 | 3.89 |
| 387.37 | 2.96 | 2.96 |
| 419.38 | 3.70 | 3.70 |
| 383.40 | 3.13 | 3.13 |
| 449.41 | 3.71 | 3.71 |
| 449.41 | 3.71 | 3.71 |
| 379.44 | 3.30 | 3.30 |
| 430.28 | 3.44 | 3.44 |
| 365.41 | 2.99 | 2.99 |
| 385.83 | 3.34 | 3.34 |
| 413.48 | 2.42 | 2.42 |
| 369.38 | 2.82 | 2.82 |
| 385.83 | 3.34 | 3.34 |
| 396.38 | 2.59 | 2.59 |
| 385.83 | 3.34 | 3.34 |
| 385.83 | 3.34 | 3.34 |
| 397.48 | 3.40 | 3.40 |
| 435.38 | 3.41 | 3.41 |
| 393.47 | 3.81 | 3.81 |
| 399.40 | 2.83 | 2.83 |
| 430.28 | 3.44 | 3.44 |
| 427.49 | 4.35 | 4.35 |
| 399.86 | 3.90 | 3.90 |
| 453.83 | 4.35 | 4.35 |
| 403.82 | 3.47 | 3.47 |
| 420.28 | 3.99 | 3.99 |
| 429.48 | 2.09 | 2.09 |
| 420.28 | 3.99 | 3.99 |
| 367.39 | 2.39 | 2.39 |
| 381.41 | 2.69 | 2.69 |
| 401.45 | 3.83 | 3.83 |
| 437.37 | 3.84 | 3.84 |
| 396.38 | 2.59 | 2.59 |
| 387.44 | 2.80 | 2.80 |
| 403.82 | 3.47 | 3.47 |
| 420.28 | 3.99 | 3.99 |
| 393.47 | 3.81 | 3.81 |
| 367.39 | 2.39 | 2.39 |
| 403.82 | 3.47 | 3.47 |
| 499.17 | 4.75 | 4.75 |
| 385.83 | 3.34 | 3.34 |
| 430.28 | 3.44 | 3.44 |
| 433.41 | 4.26 | 4.26 |
| 393.47 | 3.81 | 3.81 |
| 419.38 | 3.70 | 3.70 |
| 369.38 | 2.82 | 2.82 |
| 367.39 | 2.39 | 2.39 |
| 365.41 | 3.24 | 3.24 |
| 351.39 | 2.68 | 2.68 |
| 337.36 | 2.62 | 2.62 |
| 369.38 | 2.82 | 2.82 |
| 383.39 | 2.09 | 2.09 |
| 387.37 | 2.96 | 2.96 |
| 427.49 | 4.35 | 4.35 |
| 453.91 | 4.49 | 4.49 |