ID: ALA641353
Type: Binding
Description: Inhibition of aldose reductase (aldo-keto reductase, AKR1B1) isolated from human placenta.
Bioactivity
Activity Types for Assay ALA641353
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
391.20 | 2.97 | 2.97 |
419.38 | 3.70 | 3.70 |
352.38 | 2.08 | 2.08 |
411.44 | 2.70 | 2.70 |
381.41 | 2.69 | 2.69 |
420.28 | 3.99 | 3.99 |
381.41 | 2.69 | 2.69 |
487.38 | 4.72 | 4.72 |
381.41 | 2.69 | 2.69 |
453.83 | 4.35 | 4.35 |
437.37 | 3.84 | 3.84 |
381.41 | 2.69 | 2.69 |
365.41 | 2.99 | 2.99 |
365.41 | 2.99 | 2.99 |
415.47 | 4.14 | 4.14 |
435.89 | 4.49 | 4.49 |
420.28 | 3.99 | 3.99 |
387.37 | 2.96 | 2.96 |
420.28 | 3.99 | 3.99 |
329.31 | 2.02 | 2.02 |
384.85 | 3.00 | 3.00 |
365.41 | 2.99 | 2.99 |
430.28 | 3.44 | 3.44 |
385.83 | 3.34 | 3.34 |
387.37 | 2.96 | 2.96 |
419.38 | 3.70 | 3.70 |
430.28 | 3.44 | 3.44 |
419.38 | 3.70 | 3.70 |
383.45 | 3.38 | 3.38 |
419.38 | 3.70 | 3.70 |
433.41 | 3.89 | 3.89 |
387.37 | 2.96 | 2.96 |
419.38 | 3.70 | 3.70 |
383.40 | 3.13 | 3.13 |
449.41 | 3.71 | 3.71 |
449.41 | 3.71 | 3.71 |
379.44 | 3.30 | 3.30 |
430.28 | 3.44 | 3.44 |
365.41 | 2.99 | 2.99 |
385.83 | 3.34 | 3.34 |
413.48 | 2.42 | 2.42 |
369.38 | 2.82 | 2.82 |
385.83 | 3.34 | 3.34 |
396.38 | 2.59 | 2.59 |
385.83 | 3.34 | 3.34 |
385.83 | 3.34 | 3.34 |
397.48 | 3.40 | 3.40 |
435.38 | 3.41 | 3.41 |
393.47 | 3.81 | 3.81 |
399.40 | 2.83 | 2.83 |
430.28 | 3.44 | 3.44 |
427.49 | 4.35 | 4.35 |
399.86 | 3.90 | 3.90 |
453.83 | 4.35 | 4.35 |
403.82 | 3.47 | 3.47 |
420.28 | 3.99 | 3.99 |
429.48 | 2.09 | 2.09 |
420.28 | 3.99 | 3.99 |
367.39 | 2.39 | 2.39 |
381.41 | 2.69 | 2.69 |
401.45 | 3.83 | 3.83 |
437.37 | 3.84 | 3.84 |
396.38 | 2.59 | 2.59 |
387.44 | 2.80 | 2.80 |
403.82 | 3.47 | 3.47 |
420.28 | 3.99 | 3.99 |
393.47 | 3.81 | 3.81 |
367.39 | 2.39 | 2.39 |
403.82 | 3.47 | 3.47 |
499.17 | 4.75 | 4.75 |
385.83 | 3.34 | 3.34 |
430.28 | 3.44 | 3.44 |
433.41 | 4.26 | 4.26 |
393.47 | 3.81 | 3.81 |
419.38 | 3.70 | 3.70 |
369.38 | 2.82 | 2.82 |
367.39 | 2.39 | 2.39 |
365.41 | 3.24 | 3.24 |
351.39 | 2.68 | 2.68 |
337.36 | 2.62 | 2.62 |
369.38 | 2.82 | 2.82 |
383.39 | 2.09 | 2.09 |
387.37 | 2.96 | 2.96 |
427.49 | 4.35 | 4.35 |
453.91 | 4.49 | 4.49 |