Basic Information
ID: ALA643363
Type: Binding
Description: Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsome
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA643363
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 280.40 | 4.86 | 4.86 |
| 350.49 | 5.40 | 5.40 |
| 349.46 | 4.11 | 4.11 |
| 445.37 | 6.40 | 6.40 |
| 404.54 | 5.71 | 5.71 |
| 440.57 | 4.29 | 4.29 |
| 412.46 | 5.38 | 5.38 |
| 537.51 | 6.38 | 6.38 |
| 376.48 | 5.10 | 5.10 |
| 384.93 | 6.06 | 6.06 |
| 380.51 | 5.38 | 5.38 |
| 382.53 | 5.63 | 5.63 |
| 368.50 | 5.23 | 5.23 |
| 366.49 | 4.99 | 4.99 |
| 352.46 | 4.60 | 4.60 |
| 410.54 | 4.74 | 4.74 |
| 410.54 | 4.74 | 4.74 |
| 348.52 | 6.42 | 6.42 |
| 342.47 | 6.04 | 6.04 |
| 463.39 | 5.60 | 5.60 |
| 463.39 | 5.60 | 5.60 |
| 340.45 | 4.45 | 4.45 |
| 338.43 | 4.21 | 4.21 |
| 454.55 | 4.31 | 4.31 |
| 394.50 | 4.29 | 4.29 |
| 445.37 | 6.40 | 6.40 |
| 454.55 | 4.31 | 4.31 |
| 380.47 | 3.90 | 3.90 |
| 363.49 | 4.50 | 4.50 |
| 364.47 | 4.93 | 4.93 |
| 463.39 | 5.60 | 5.60 |
| 396.51 | 4.35 | 4.35 |
| 430.48 | 4.57 | 4.57 |
| 392.52 | 5.57 | 5.57 |
| 410.54 | 4.74 | 4.74 |
| 396.51 | 4.08 | 4.08 |
| 394.50 | 4.29 | 4.29 |
| 454.55 | 4.31 | 4.31 |
| 1060.98 | ||
| 817.05 | ||
| 845.10 | ||
| 845.10 | ||
| 957.32 |