Basic Information
ID: ALA646770
Type: Functional
Description: Ability to antagonize the inhibitory effect of clonidine on the mouse vas deferens is the presynaptic alpha-2 adrenergic receptor antagonist potency relative to idazoxan = 1.
Tissue: Vas deferens
Activity Charts
Bioactivity
Activity Types for Assay ALA646770
Antagonist potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 202.26 | 1.24 | 1.24 |
| 190.20 | 0.79 | 0.79 |
| 202.26 | 1.38 | 1.38 |
| 218.26 | 1.22 | 1.22 |
| 204.23 | 1.18 | 1.18 |
| 252.75 | 1.61 | 1.61 |
| 303.59 | 1.75 | 1.75 |
| 285.14 | 0.70 | 0.70 |
| 266.77 | 2.16 | 2.16 |
| 285.14 | 0.70 | 0.70 |
| 266.73 | 1.19 | 1.19 |
| 252.75 | 1.61 | 1.61 |
| 252.75 | 1.61 | 1.61 |
| 238.72 | 1.38 | 1.38 |
| 238.72 | 1.30 | 1.30 |
| 238.72 | 1.55 | 1.55 |
| 238.72 | 1.30 | 1.30 |
| 224.69 | 0.99 | 0.99 |
| 293.58 | 2.30 | 2.30 |
| 285.14 | 0.70 | 0.70 |
| 259.14 | 1.65 | 1.65 |
| 259.14 | 1.65 | 1.65 |
| 238.74 | 2.25 | 2.25 |
| 254.72 | 1.00 | 1.00 |
| 238.72 | 1.30 | 1.30 |
| 222.68 | 1.78 | 1.78 |
| 254.72 | 1.00 | 1.00 |
| 328.84 | 2.99 | 2.99 |
| 294.83 | 2.94 | 2.94 |
| 254.72 | 1.00 | 1.00 |
| 259.14 | 1.65 | 1.65 |
| 238.72 | 1.30 | 1.30 |
| 273.16 | 1.95 | 1.95 |
| 252.75 | 1.77 | 1.77 |
| 240.76 | 1.71 | 1.71 |
| 293.58 | 2.30 | 2.30 |
| 242.68 | 1.13 | 1.13 |