Basic Information
ID: ALA648847
Type: Functional
Description: In vitro antagonistic activity for angiotensin II receptor, type 1 by displacing 125I[Sar, ILe8 ]AII radioligand in rabbit aorta membrane without using bovine serum albumin (BSA)
Organism: Oryctolagus cuniculus
Tissue: Aorta
Subcellular Fraction: Membrane
Activity Charts
Bioactivity
Activity Types for Assay ALA648847
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 520.42 | 5.58 | 5.58 |
| 485.98 | 4.93 | 4.93 |
| 445.57 | 4.33 | 4.33 |
| 519.53 | 5.29 | 5.29 |
| 436.90 | 4.47 | 4.47 |
| 375.44 | 3.22 | 3.22 |
| 509.57 | 4.03 | 4.03 |
| 523.60 | 4.05 | 4.05 |
| 509.57 | 3.96 | 3.96 |
| 465.56 | 4.58 | 4.58 |
| 481.56 | 4.28 | 4.28 |
| 496.53 | 4.18 | 4.18 |
| 500.01 | 5.17 | 5.17 |
| 465.56 | 4.58 | 4.58 |
| 500.01 | 5.32 | 5.32 |
| 483.96 | 4.54 | 4.54 |
| 555.51 | 5.03 | 5.03 |
| 523.60 | 4.12 | 4.12 |
| 523.60 | 4.12 | 4.12 |
| 479.59 | 4.89 | 4.89 |
| 471.95 | 4.54 | 4.54 |
| 523.60 | 4.12 | 4.12 |
| 447.50 | 2.93 | 2.93 |
| 461.53 | 3.02 | 3.02 |
| 433.52 | 2.84 | 2.84 |
| 460.54 | 2.59 | 2.59 |
| 463.55 | 4.06 | 4.06 |
| 656.79 | 6.51 | 6.51 |
| 527.63 | 5.94 | 5.94 |
| 493.62 | 5.40 | 5.40 |
| 609.70 | 5.18 | 5.18 |
| 566.67 | 5.87 | 5.87 |
| 465.56 | 4.58 | 4.58 |
| 443.56 | 4.40 | 4.40 |
| 481.56 | 4.28 | 4.28 |
| 451.53 | 4.27 | 4.27 |
| 477.57 | 4.14 | 4.14 |
| 494.60 | 4.34 | 4.34 |
| 496.53 | 4.18 | 4.18 |
| 485.98 | 4.93 | 4.93 |
| 431.54 | 4.25 | 4.25 |
| 417.52 | 3.69 | 3.69 |
| 415.50 | 3.62 | 3.62 |
| 417.52 | 3.86 | 3.86 |
| 431.54 | 4.08 | 4.08 |
| 403.49 | 3.30 | 3.30 |
| 469.94 | 4.46 | 4.46 |
| 465.56 | 4.33 | 4.33 |
| 389.46 | 2.82 | 2.82 |
| 479.59 | 4.64 | 4.64 |
| 493.57 | 4.17 | 4.17 |
| 459.55 | 3.37 | 3.37 |
| 479.59 | 4.64 | 4.64 |
| 471.61 | 4.86 | 4.86 |
| 482.50 | 3.79 | 3.79 |
| 475.55 | 3.56 | 3.56 |
| 541.48 | 4.97 | 4.97 |
| 526.56 | 4.19 | 4.19 |
| 493.62 | 4.92 | 4.92 |
| 479.59 | 4.53 | 4.53 |
| 480.49 | 3.72 | 3.72 |
| 452.52 | 3.67 | 3.67 |
| 510.56 | 4.57 | 4.57 |
| 489.58 | 3.65 | 3.65 |
| 504.97 | 5.03 | 5.03 |
| 541.66 | 5.86 | 5.86 |
| 509.57 | 4.06 | 4.06 |
| 466.55 | 3.85 | 3.85 |
| 469.52 | 4.41 | 4.41 |
| 530.43 | 5.03 | 5.03 |
| 495.54 | 3.97 | 3.97 |
| 414.47 | 2.81 | 2.81 |
| 457.46 | 3.85 | 3.85 |
| 509.57 | 4.06 | 4.06 |
| 469.52 | 4.41 | 4.41 |
| 447.50 | 2.46 | 2.46 |
| 479.59 | 4.83 | 4.83 |
| 481.56 | 4.28 | 4.28 |
| 496.53 | 4.18 | 4.18 |
| 485.98 | 4.93 | 4.93 |
| 431.54 | 4.04 | 4.04 |
| 429.53 | 3.69 | 3.69 |
| 431.54 | 3.94 | 3.94 |
| 580.69 | 4.94 | 4.94 |
| 566.67 | 4.95 | 4.95 |
| 497.63 | 5.03 | 5.03 |
| 516.01 | 4.97 | 4.97 |
| 493.62 | 4.77 | 4.77 |
| 515.62 | 5.48 | 5.48 |
| 515.62 | 5.48 | 5.48 |
| 422.92 | 4.27 | 4.27 |