Basic Information
ID: ALA651146
Type: Binding
Description: Dose necessary to produce 50% of the isoprenaline effect to inhibit GDP binding to beta-3 adrenergic receptor in brown adipose tissue (BAT mitochondria) of rats after subcutaneous administration.
Tissue: Adipose tissue
Subcellular Fraction: Mitochondria
Activity Charts
Bioactivity
Activity Types for Assay ALA651146
ED50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 211.26 | 1.13 | 1.13 |
| 417.50 | 2.82 | 2.82 |
| 373.45 | 2.20 | 2.20 |
| 375.42 | 1.65 | 1.65 |
| 389.45 | 2.04 | 2.04 |
| 361.39 | 1.56 | 1.56 |
| 375.42 | 1.65 | 1.65 |
| 377.87 | 3.15 | 3.15 |
| 314.38 | 1.45 | 1.45 |
| 287.36 | 2.09 | 2.09 |
| 359.42 | 1.81 | 1.81 |
| 361.39 | 1.56 | 1.56 |
| 277.19 | 3.00 | 3.00 |
| 313.40 | 2.73 | 2.73 |
| 343.42 | 2.43 | 2.43 |
| 403.48 | 2.43 | 2.43 |
| 389.45 | 2.04 | 2.04 |
| 225.29 | 1.13 | 1.13 |
| 427.88 | 1.35 | 1.35 |
| 446.33 | 2.30 | 2.30 |
| 429.87 | 1.79 | 1.79 |
| 429.87 | 1.79 | 1.79 |
| 446.33 | 2.30 | 2.30 |
| 415.85 | 1.70 | 1.70 |
| 429.87 | 1.79 | 1.79 |
| 375.42 | 1.65 | 1.65 |
| 407.46 | 2.04 | 2.04 |
| 397.86 | 1.56 | 1.56 |