Basic Information
ID: ALA653263
Type: Functional
Description: In vitro multi drug resistance (MDR) reversal inhibitory activity against CCRF-CEM/VCR-1000 cell line
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CCRF-CEM/VCR-1000
Target: CCRF-CEM/VCR-1000(ALA614540)
Document: ALA1145893
In vitro multi drug resistance (MDR) reversal inhibitory activity against CCRF-CEM/VCR-1000 cell line: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA653263
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 341.45 | 3.24 | 3.24 |
| 323.44 | 4.25 | 4.25 |
| 458.60 | 4.37 | 4.37 |
| 462.57 | 4.20 | 4.20 |
| 353.46 | 3.34 | 3.34 |
| 369.46 | 2.57 | 2.57 |
| 355.48 | 3.58 | 3.58 |
| 355.48 | 3.58 | 3.58 |
| 367.49 | 3.73 | 3.73 |
| 383.53 | 4.36 | 4.36 |
| 474.60 | 4.07 | 4.07 |
| 247.34 | 3.03 | 3.03 |
| 293.36 | 1.35 | 1.35 |
| 372.44 | 2.59 | 2.59 |
| 327.42 | 2.80 | 2.80 |
| 456.59 | 5.08 | 5.08 |
| 307.44 | 4.76 | 4.76 |
| 454.57 | 5.23 | 5.23 |
| 307.44 | 4.76 | 4.76 |
| 389.50 | 4.03 | 4.03 |
| 367.49 | 3.73 | 3.73 |
| 383.53 | 4.36 | 4.36 |
| 462.57 | 4.20 | 4.20 |
| 464.58 | 4.05 | 4.05 |
| 459.59 | 4.23 | 4.23 |
| 369.51 | 3.58 | 3.58 |
| 385.50 | 3.08 | 3.08 |
| 279.34 | 0.96 | 0.96 |
| 372.44 | 2.59 | 2.59 |
| 431.53 | 3.64 | 3.64 |
| 434.51 | 3.62 | 3.62 |
| 383.49 | 3.00 | 3.00 |
| 291.39 | 2.50 | 2.50 |
| 489.66 | 5.94 | 5.94 |
| 369.46 | 2.57 | 2.57 |
| 447.58 | 4.82 | 4.82 |
| 383.49 | 3.43 | 3.43 |
| 474.60 | 3.77 | 3.77 |
| 357.45 | 2.95 | 2.95 |
| 564.73 | 5.64 | 5.64 |
| 493.65 | 6.05 | 6.05 |
| 458.60 | 4.06 | 4.06 |
| 277.36 | 2.11 | 2.11 |
| 385.55 | 4.21 | 4.21 |
| 417.55 | 4.88 | 4.88 |
| 474.60 | 4.07 | 4.07 |
| 369.46 | 2.61 | 2.61 |
| 509.69 | 6.56 | 6.56 |
| 399.58 | 4.87 | 4.87 |
| 478.61 | 4.71 | 4.71 |
| 383.53 | 4.23 | 4.23 |
| 371.48 | 2.42 | 2.42 |
| 474.60 | 4.07 | 4.07 |
| 465.59 | 5.62 | 5.62 |
| 433.50 | 4.14 | 4.14 |
| 381.52 | 4.16 | 4.16 |
| 375.47 | 4.35 | 4.35 |
| 444.58 | 4.06 | 4.06 |
| 473.61 | 5.31 | 5.31 |
| 277.36 | 2.11 | 2.11 |
| 509.65 | 5.38 | 5.38 |
| 462.57 | 4.20 | 4.20 |
| 367.49 | 3.73 | 3.73 |
| 419.52 | 3.73 | 3.73 |
| 433.59 | 5.51 | 5.51 |
| 399.53 | 4.07 | 4.07 |
| 479.62 | 5.66 | 5.66 |
| 543.71 | 7.21 | 7.21 |
| 279.34 | 0.96 | 0.96 |
| 372.44 | 2.59 | 2.59 |