Basic Information
ID: ALA653496
Type: Binding
Description: Inhibition of human brain beta-secretase, using MBPC125Swe (maltose-binding-protein C-125 Swedish) assay
Cell type: PC-12
Activity Charts
Bioactivity
Activity Types for Assay ALA653496
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1651.83 | ||
| 2066.21 | ||
| 2140.38 | ||
| 2121.38 | ||
| 2064.28 | ||
| 2092.34 | ||
| 2151.32 | ||
| 2142.31 | ||
| 2126.33 | ||
| 2106.36 | ||
| 2050.26 | ||
| 2132.27 | ||
| 2094.26 | ||
| 2124.25 | ||
| 877.01 | -1.40 | -1.40 |
| 2052.18 | ||
| 2108.29 | ||
| 735.84 | -1.72 | -1.72 |
| 746.93 | -0.25 | -0.25 |
| 892.09 | 0.32 | 0.32 |
| 866.05 | -0.16 | -0.16 |
| 934.17 | 1.40 | 1.40 |
| 928.12 | 0.67 | 0.67 |
| 546.73 | 0.89 | 0.89 |
| 894.10 | 0.47 | 0.47 |
| 942.15 | 1.06 | 1.06 |
| 851.08 | 1.61 | 1.61 |
| 617.81 | 0.40 | 0.40 |
| 896.07 | -0.80 | -0.80 |
| 1667.79 | ||
| 1823.98 | ||
| 2096.24 | ||
| 834.97 | -1.58 | -1.58 |
| 1667.79 | ||
| 833.96 | -1.93 | -1.93 |
| 836.07 | 0.63 | 0.63 |
| 818.00 | -0.75 | -0.75 |
| 832.03 | -0.36 | -0.36 |
| 964.08 | -2.23 | -2.23 |
| 936.03 | -2.87 | -2.87 |
| 1623.78 | ||
| 1709.82 |