Basic Information
ID: ALA653497
Type: Binding
Description: Inhibition of human beta-secretase (BACE) in MBP-C125 assay
Activity Charts
Bioactivity
Activity Types for Assay ALA653497
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 763.89 | 0.81 | 0.81 |
| 829.95 | 1.34 | 1.34 |
| 894.10 | 0.47 | 0.47 |
| 755.87 | 0.81 | 0.81 |
| 861.99 | 2.39 | 2.39 |
| 847.96 | 2.60 | 2.60 |
| 847.96 | 2.60 | 2.60 |
| 815.97 | 2.99 | 2.99 |
| 751.82 | 3.53 | 3.53 |
| 655.79 | 2.54 | 2.54 |
| 627.74 | 2.37 | 2.37 |
| 591.71 | 3.31 | 3.31 |
| 775.85 | 1.60 | 1.60 |
| 739.87 | 1.32 | 1.32 |
| 789.93 | 2.47 | 2.47 |
| 737.96 | 3.24 | 3.24 |
| 775.90 | 2.54 | 2.54 |
| 783.92 | 1.93 | 1.93 |
| 620.54 | 2.92 | 2.92 |
| 737.96 | 3.21 | 3.21 |
| 685.97 | 3.65 | 3.65 |
| 805.93 | 1.96 | 1.96 |
| 834.76 | 1.57 | 1.57 |
| 802.04 | 2.44 | 2.44 |
| 737.96 | 3.21 | 3.21 |
| 675.89 | 1.79 | 1.79 |
| 703.94 | 2.27 | 2.27 |
| 619.83 | 1.70 | 1.70 |
| 659.93 | 3.11 | 3.11 |
| 693.95 | 3.51 | 3.51 |
| 783.92 | 1.64 | 1.64 |
| 769.89 | 1.46 | 1.46 |
| 797.95 | 2.57 | 2.57 |
| 781.95 | 2.59 | 2.59 |
| 689.92 | 2.18 | 2.18 |
| 773.99 | 2.27 | 2.27 |
| 767.99 | 2.98 | 2.98 |
| 694.94 | 2.91 | 2.91 |