Basic Information
ID: ALA654358
Type: Functional
Description: In vitro inhibition of human recombinant IL-1-beta-induced breakdown of bovine cartilage in a cartilage organ culture assay
Organism: Bos taurus
Activity Charts
Bioactivity
Activity Types for Assay ALA654358
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 357.79 | 3.93 | 3.93 |
| 162.19 | 0.93 | 0.93 |
| 230.26 | 3.04 | 3.04 |
| 256.33 | 3.06 | 3.06 |
| 262.72 | 3.10 | 3.10 |
| 228.28 | 2.45 | 2.45 |
| 258.30 | 2.46 | 2.46 |
| 273.27 | 2.36 | 2.36 |
| 229.26 | 1.84 | 1.84 |
| 258.30 | 2.46 | 2.46 |
| 288.33 | 2.46 | 2.46 |
| 288.33 | 2.46 | 2.46 |
| 318.35 | 2.47 | 2.47 |
| 318.35 | 2.47 | 2.47 |
| 244.28 | 2.15 | 2.15 |
| 322.77 | 3.12 | 3.12 |
| 299.36 | 2.15 | 2.15 |
| 288.33 | 2.46 | 2.46 |
| 288.33 | 2.46 | 2.46 |
| 307.17 | 3.21 | 3.21 |
| 312.44 | 4.69 | 4.69 |
| 284.38 | 3.57 | 3.57 |
| 228.28 | 2.45 | 2.45 |
| 354.17 | 3.05 | 3.05 |
| 330.72 | 4.12 | 4.12 |
| 292.75 | 3.11 | 3.11 |
| 285.33 | 2.41 | 2.41 |
| 300.34 | 2.62 | 2.62 |
| 286.31 | 2.23 | 2.23 |
| 278.34 | 3.60 | 3.60 |
| 316.34 | 2.24 | 2.24 |
| 315.35 | 3.02 | 3.02 |
| 262.72 | 3.10 | 3.10 |
| 246.27 | 2.59 | 2.59 |
| 326.30 | 3.47 | 3.47 |
| 258.30 | 2.46 | 2.46 |
| 228.28 | 2.45 | 2.45 |
| 316.34 | 2.24 | 2.24 |
| 316.34 | 2.24 | 2.24 |
| 286.31 | 2.23 | 2.23 |
| 300.34 | 2.20 | 2.20 |
| 258.30 | 2.46 | 2.46 |
| 258.30 | 2.46 | 2.46 |
| 285.33 | 2.41 | 2.41 |
| 444.44 | -0.21 | -0.21 |