Basic Information
ID: ALA654485
Type: Binding
Description: Inhibition of GDP binding against beta-3 adrenergic receptor in brown adipose tissue (BAT) mitochondria of rats after peroral administration (Dose necessary to produce 50% of the isoprenaline effect).
Tissue: Adipose tissue
Subcellular Fraction: Mitochondria
Activity Charts
Bioactivity
Activity Types for Assay ALA654485
GDP ED50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 400.48 | 1.78 | 1.78 |
| 416.52 | 2.25 | 2.25 |
| 416.52 | 2.34 | 2.34 |
| 428.53 | 2.49 | 2.49 |
| 464.56 | 3.13 | 3.13 |
| 414.50 | 2.10 | 2.10 |
| 417.46 | 0.08 | 0.08 |
| 418.49 | 1.24 | 1.24 |
| 375.43 | 0.46 | 0.46 |
| 376.41 | 0.98 | 0.98 |
| 436.51 | 3.11 | 3.11 |
| 428.53 | 2.53 | 2.53 |
| 404.46 | 0.58 | 0.58 |
| 374.44 | 1.22 | 1.22 |
| 402.49 | 2.00 | 2.00 |
| 360.41 | 0.96 | 0.96 |
| 400.48 | 1.75 | 1.75 |
| 416.52 | 2.39 | 2.39 |
| 462.55 | 3.02 | 3.02 |
| 416.52 | 2.39 | 2.39 |
| 476.57 | 3.06 | 3.06 |
| 430.50 | 1.33 | 1.33 |
| 464.56 | 3.35 | 3.35 |
| 464.56 | 2.83 | 2.83 |
| 388.46 | 1.56 | 1.56 |
| 470.59 | 3.12 | 3.12 |
| 432.52 | 1.63 | 1.63 |
| 519.43 | 4.10 | 4.10 |
| 418.49 | 0.97 | 0.97 |
| 454.52 | 2.41 | 2.41 |
| 484.98 | 3.44 | 3.44 |
| 466.53 | 2.72 | 2.72 |
| 432.52 | 1.62 | 1.62 |
| 450.54 | 2.79 | 2.79 |
| 388.46 | 1.61 | 1.61 |
| 480.56 | 2.67 | 2.67 |
| 378.40 | 1.10 | 1.10 |
| 446.52 | 2.63 | 2.63 |
| 392.43 | 1.36 | 1.36 |
| 388.46 | 1.61 | 1.61 |
| 374.44 | 1.22 | 1.22 |
| 416.47 | 1.64 | 1.64 |
| 414.50 | 2.16 | 2.16 |
| 418.49 | 1.24 | 1.24 |
| 418.49 | 1.24 | 1.24 |
| 436.51 | 0.97 | 0.97 |
| 404.46 | 0.58 | 0.58 |
| 374.44 | 1.22 | 1.22 |
| 434.49 | 0.94 | 0.94 |