Basic Information
ID: ALA656719
Type: Functional
Description: Reversal of sensitivity of multidrug resistant chinese hamster ovary cell line CHRC/5 expressed as concentration that restores 50% of cytotoxic activity of 5 ug/mL toward doxorubicin
Organism: Cricetulus griseus
Cell type: CHRC5 cell line
Activity Charts
Bioactivity
Activity Types for Assay ALA656719
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.61 | 5.09 | 5.09 |
| 645.32 | 6.94 | 6.94 |
| 469.63 | 6.30 | 6.30 |
| 583.66 | 6.71 | 6.71 |
| 581.67 | 6.19 | 6.19 |
| 579.70 | 6.88 | 6.88 |
| 655.70 | 6.44 | 6.44 |
| 535.64 | 6.35 | 6.35 |
| 539.61 | 6.18 | 6.18 |
| 564.69 | 6.40 | 6.40 |
| 551.64 | 6.05 | 6.05 |
| 547.66 | 6.59 | 6.59 |
| 533.63 | 6.51 | 6.51 |
| 567.71 | 6.98 | 6.98 |
| 522.61 | 5.56 | 5.56 |
| 599.66 | 6.41 | 6.41 |
| 553.63 | 6.49 | 6.49 |
| 552.63 | 5.77 | 5.77 |
| 523.66 | 6.58 | 6.58 |
| 577.68 | 6.36 | 6.36 |
| 563.65 | 5.97 | 5.97 |
| 568.70 | 6.24 | 6.24 |
| 549.67 | 6.82 | 6.82 |
| 537.62 | 5.87 | 5.87 |
| 581.67 | 6.05 | 6.05 |
| 551.64 | 6.26 | 6.26 |
| 563.70 | 7.21 | 7.21 |
| 535.64 | 6.43 | 6.43 |
| 569.63 | 6.19 | 6.19 |
| 552.63 | 4.67 | 4.67 |
| 551.62 | 6.10 | 6.10 |
| 579.70 | 6.83 | 6.83 |
| 566.61 | 5.95 | 5.95 |
| 583.66 | 6.58 | 6.58 |
| 653.69 | 5.97 | 5.97 |
| 565.67 | 6.44 | 6.44 |
| 551.64 | 6.05 | 6.05 |
| 535.64 | 5.64 | 5.64 |
| 507.59 | 6.00 | 6.00 |
| 521.62 | 6.04 | 6.04 |
| 595.70 | 6.58 | 6.58 |
| 549.67 | 6.65 | 6.65 |
| 595.70 | 6.44 | 6.44 |
| 597.69 | 6.97 | 6.97 |
| 563.65 | 5.56 | 5.56 |
| 563.65 | 5.98 | 5.98 |
| 565.67 | 5.89 | 5.89 |
| 606.55 | 6.86 | 6.86 |
| 491.59 | 5.83 | 5.83 |
| 540.62 | 6.41 | 6.41 |
| 503.60 | 5.76 | 5.76 |
| 495.55 | 5.58 | 5.58 |
| 564.64 | 5.28 | 5.28 |
| 521.57 | 5.17 | 5.17 |
| 507.59 | 5.45 | 5.45 |
| 555.70 | 6.72 | 6.72 |
| 477.56 | 5.44 | 5.44 |
| 491.59 | 5.75 | 5.75 |
| 507.59 | 5.45 | 5.45 |
| 537.62 | 5.51 | 5.51 |
| 563.65 | 5.78 | 5.78 |
| 545.56 | 6.46 | 6.46 |