Basic Information
ID: ALA657287
Type: Binding
Description: In vitro inhibitory activity against human cathepsin B, using 2 uM of Z -Leu-Arg-AMC as substrate
Activity Charts
Bioactivity
Activity Types for Assay ALA657287
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.45 | 2.29 | 2.29 |
| 404.56 | 3.87 | 3.87 |
| 434.58 | 3.24 | 3.24 |
| 446.64 | 5.04 | 5.04 |
| 446.60 | 3.83 | 3.83 |
| 374.45 | 3.10 | 3.10 |
| 349.43 | 3.22 | 3.22 |
| 306.41 | 4.12 | 4.12 |
| 306.41 | 4.12 | 4.12 |
| 313.43 | 3.58 | 3.58 |
| 384.50 | 3.53 | 3.53 |
| 391.52 | 3.96 | 3.96 |
| 390.53 | 3.63 | 3.63 |
| 461.65 | 3.98 | 3.98 |
| 438.58 | 4.07 | 4.07 |
| 462.64 | 4.02 | 4.02 |
| 402.54 | 3.63 | 3.63 |
| 307.40 | 3.52 | 3.52 |
| 308.39 | 2.91 | 2.91 |
| 391.52 | 3.78 | 3.78 |
| 345.45 | 4.60 | 4.60 |
| 490.65 | 5.18 | 5.18 |
| 415.58 | 4.86 | 4.86 |
| 389.54 | 4.59 | 4.59 |
| 387.53 | 4.50 | 4.50 |
| 307.40 | 3.52 | 3.52 |
| 273.34 | 1.47 | 1.47 |
| 391.52 | 3.78 | 3.78 |
| 307.40 | 3.52 | 3.52 |
| 419.40 | 4.25 | 4.25 |
| 390.53 | 3.53 | 3.53 |
| 390.53 | 3.36 | 3.36 |
| 345.45 | 4.60 | 4.60 |
| 383.50 | 5.19 | 5.19 |
| 416.57 | 4.02 | 4.02 |
| 418.59 | 4.26 | 4.26 |
| 390.53 | 3.53 | 3.53 |
| 404.56 | 3.87 | 3.87 |