Basic Information
ID: ALA657821
Type: Binding
Description: Inhibitory activity against human carbonic anhydrase I (CA1)
Activity Charts
Bioactivity
Activity Types for Assay ALA657821
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 200.26 | -0.16 | -0.16 |
| 265.30 | 0.45 | 0.45 |
| 285.73 | -0.78 | -0.78 |
| 230.27 | 0.65 | 0.65 |
| 327.39 | 0.72 | 0.72 |
| 335.39 | -0.43 | -0.43 |
| 201.25 | -0.13 | -0.13 |
| 187.22 | -0.17 | -0.17 |
| 172.21 | -0.08 | -0.08 |
| 194.24 | -1.39 | -1.39 |
| 180.21 | -1.23 | -1.23 |
| 172.21 | -0.08 | -0.08 |
| 298.11 | 0.52 | 0.52 |
| 251.10 | 0.68 | 0.68 |
| 190.20 | 0.06 | 0.06 |
| 319.29 | -0.42 | -0.42 |
| 186.24 | -0.21 | -0.21 |
| 206.65 | 0.57 | 0.57 |
| 187.22 | -0.38 | -0.38 |
| 172.21 | -0.08 | -0.08 |
| 327.39 | 0.72 | 0.72 |
| 251.29 | -1.53 | -1.53 |
| 349.42 | -1.00 | -1.00 |
| 320.18 | -0.13 | -0.13 |
| 229.29 | 0.53 | 0.53 |
| 274.32 | 0.31 | 0.31 |
| 707.23 | 4.97 | 4.97 |
| 524.00 | 3.05 | 3.05 |
| 526.96 | 1.72 | 1.72 |
| 433.87 | 1.19 | 1.19 |
| 495.94 | 2.54 | 2.54 |
| 552.05 | 4.17 | 4.17 |
| 513.93 | 2.68 | 2.68 |
| 643.91 | 2.50 | 2.50 |
| 645.14 | 4.71 | 4.71 |
| 617.08 | 3.59 | 3.59 |
| 589.03 | 3.08 | 3.08 |
| 495.94 | 2.54 | 2.54 |
| 649.89 | 3.66 | 3.66 |
| 580.95 | 0.85 | 0.85 |
| 524.00 | 2.26 | 2.26 |
| 448.88 | 1.29 | 1.29 |
| 574.84 | 3.31 | 3.31 |
| 538.02 | 2.73 | 2.73 |
| 567.06 | 3.68 | 3.68 |
| 510.96 | 2.05 | 2.05 |
| 512.77 | 1.95 | 1.95 |
| 524.98 | 2.69 | 2.69 |
| 654.16 | 4.77 | 4.77 |
| 626.11 | 3.65 | 3.65 |
| 455.90 | -0.53 | -0.53 |
| 699.13 | 3.84 | 3.84 |
| 597.05 | 0.84 | 0.84 |
| 673.15 | 1.63 | 1.63 |
| 589.05 | 1.99 | 1.99 |
| 539.01 | 2.56 | 2.56 |
| 671.07 | 2.72 | 2.72 |
| 643.02 | 2.21 | 2.21 |
| 560.05 | 3.03 | 3.03 |
| 447.90 | 0.86 | 0.86 |
| 659.12 | 2.20 | 2.20 |
| 433.87 | 1.19 | 1.19 |
| 679.17 | 3.85 | 3.85 |
| 651.12 | 3.34 | 3.34 |
| 581.09 | 4.32 | 4.32 |
| 517.97 | 0.83 | 0.83 |
| 448.89 | 0.69 | 0.69 |
| 637.52 | 2.35 | 2.35 |
| 461.92 | 0.91 | 0.91 |
| 729.26 | 3.26 | 3.26 |
| 665.57 | 3.47 | 3.47 |
| 553.03 | 3.20 | 3.20 |
| 552.05 | 4.17 | 4.17 |
| 566.08 | 3.85 | 3.85 |
| 589.05 | 1.99 | 1.99 |
| 552.05 | 2.77 | 2.77 |
| 552.05 | 4.17 | 4.17 |
| 433.87 | 1.19 | 1.19 |
| 631.13 | 2.53 | 2.53 |
| 541.99 | 3.19 | 3.19 |
| 462.91 | 1.33 | 1.33 |
| 575.03 | 0.90 | 0.90 |
| 451.86 | 1.32 | 1.32 |
| 630.95 | 4.94 | 4.94 |
| 602.89 | 3.81 | 3.81 |
| 609.47 | 1.84 | 1.84 |
| 547.40 | 0.49 | 0.49 |
| 512.95 | -0.46 | -0.46 |
| 567.06 | 4.28 | 4.28 |
| 539.01 | 3.16 | 3.16 |
| 546.03 | 1.34 | 1.34 |
| 559.77 | 1.79 | 1.79 |
| 509.97 | 2.22 | 2.22 |
| 510.95 | 2.65 | 2.65 |
| 574.08 | 2.46 | 2.46 |
| 582.06 | 3.63 | 3.63 |
| 532.00 | 1.90 | 1.90 |
| 441.88 | 0.04 | 0.04 |
| 524.00 | 3.05 | 3.05 |
| 524.00 | 3.05 | 3.05 |
| 610.11 | 4.75 | 4.75 |
| 687.18 | 2.70 | 2.70 |
| 651.12 | 3.34 | 3.34 |
| 701.21 | 2.14 | 2.14 |
| 535.98 | 1.78 | 1.78 |
| 503.95 | 1.40 | 1.40 |
| 495.94 | 2.54 | 2.54 |
| 700.02 | 4.13 | 4.13 |
| 671.97 | 3.01 | 3.01 |
| 715.23 | 3.83 | 3.83 |
| 603.08 | 1.41 | 1.41 |
| 707.23 | 4.97 | 4.97 |
| 679.17 | 3.85 | 3.85 |
| 611.08 | 0.27 | 0.27 |
| 621.84 | 3.15 | 3.15 |
| 598.06 | 3.14 | 3.14 |
| 491.93 | 1.76 | 1.76 |
| 554.00 | 3.12 | 3.12 |
| 558.44 | 3.71 | 3.71 |
| 553.02 | 3.15 | 3.15 |
| 581.84 | 1.14 | 1.14 |
| 677.95 | 4.78 | 4.78 |
| 586.49 | 4.83 | 4.83 |
| 581.07 | 3.66 | 3.66 |
| 468.32 | 1.84 | 1.84 |
| 570.04 | 4.31 | 4.31 |
| 490.95 | 1.80 | 1.80 |
| 609.13 | 4.78 | 4.78 |
| 580.10 | 3.89 | 3.89 |
| 530.39 | 3.20 | 3.20 |