Basic Information
ID: ALA657828
Type: Binding
Description: Inhibitory activity against human recombinant carbonic anhydrase I (CA1)
Activity Charts
Bioactivity
Activity Types for Assay ALA657828
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 200.26 | -0.16 | -0.16 |
| 265.30 | 0.45 | 0.45 |
| 285.73 | -0.78 | -0.78 |
| 230.27 | 0.65 | 0.65 |
| 327.39 | 0.72 | 0.72 |
| 335.39 | -0.43 | -0.43 |
| 201.25 | -0.13 | -0.13 |
| 187.22 | -0.17 | -0.17 |
| 172.21 | -0.08 | -0.08 |
| 194.24 | -1.39 | -1.39 |
| 180.21 | -1.23 | -1.23 |
| 172.21 | -0.08 | -0.08 |
| 298.11 | 0.52 | 0.52 |
| 251.10 | 0.68 | 0.68 |
| 190.20 | 0.06 | 0.06 |
| 186.24 | -0.21 | -0.21 |
| 206.65 | 0.57 | 0.57 |
| 187.22 | -0.38 | -0.38 |
| 172.21 | -0.08 | -0.08 |
| 327.39 | 0.72 | 0.72 |
| 251.29 | -1.53 | -1.53 |
| 320.18 | -0.13 | -0.13 |
| 229.29 | 0.53 | 0.53 |
| 274.32 | 0.31 | 0.31 |
| 251.29 | -2.48 | -2.48 |
| 258.30 | -1.01 | -1.01 |
| 406.47 | -0.86 | -0.86 |
| 322.37 | -2.15 | -2.15 |
| 277.73 | 0.15 | 0.15 |
| 261.28 | -0.37 | -0.37 |
| 265.32 | -2.22 | -2.22 |
| 243.29 | -0.51 | -0.51 |
| 243.29 | -0.51 | -0.51 |
| 355.16 | -0.16 | -0.16 |
| 441.49 | -0.85 | -0.85 |
| 463.52 | -2.57 | -2.57 |
| 308.16 | -0.01 | -0.01 |
| 263.71 | -0.12 | -0.12 |
| 247.25 | -0.63 | -0.63 |
| 391.26 | -0.55 | -0.55 |
| 229.26 | -0.77 | -0.77 |
| 388.43 | -1.45 | -1.45 |
| 344.37 | -1.12 | -1.12 |
| 343.39 | -1.04 | -1.04 |
| 349.42 | -1.00 | -1.00 |
| 441.49 | -0.85 | -0.85 |
| 399.84 | -2.35 | -2.35 |
| 434.28 | -1.70 | -1.70 |
| 412.21 | -1.05 | -1.05 |
| 365.21 | -0.89 | -0.89 |
| 398.85 | -1.60 | -1.60 |
| 300.34 | -1.40 | -1.40 |
| 378.42 | -0.37 | -0.37 |
| 320.76 | -1.00 | -1.00 |
| 293.33 | -2.05 | -2.05 |
| 304.30 | -1.51 | -1.51 |
| 286.31 | -1.65 | -1.65 |
| 314.37 | -1.93 | -1.93 |
| 300.34 | -1.97 | -1.97 |
| 286.31 | -1.65 | -1.65 |
| 286.31 | -1.65 | -1.65 |
| 406.47 | -1.68 | -1.68 |
| 308.35 | -2.41 | -2.41 |
| 398.47 | 0.29 | 0.29 |
| 384.44 | 0.03 | 0.03 |
| 392.44 | -1.12 | -1.12 |
| 251.29 | -1.66 | -1.66 |
| 244.27 | -1.06 | -1.06 |
| 331.38 | -0.57 | -0.57 |
| 342.79 | -1.47 | -1.47 |
| 356.81 | -1.21 | -1.21 |
| 369.18 | 0.10 | 0.10 |
| 322.18 | 0.25 | 0.25 |
| 237.27 | -1.92 | -1.92 |
| 301.32 | -1.94 | -1.94 |
| 257.31 | -1.05 | -1.05 |
| 243.29 | -1.09 | -1.09 |
| 315.35 | -1.90 | -1.90 |
| 379.40 | -1.12 | -1.12 |
| 301.33 | -2.15 | -2.15 |
| 377.23 | -0.81 | -0.81 |
| 365.40 | -3.29 | -3.29 |
| 294.32 | -2.80 | -2.80 |
| 440.51 | -0.10 | -0.10 |
| 258.30 | -1.00 | -1.00 |
| 243.29 | -0.51 | -0.51 |
| 244.28 | -1.26 | -1.26 |
| 308.35 | -3.37 | -3.37 |
| 449.50 | -2.00 | -2.00 |
| 342.41 | -0.29 | -0.29 |
| 440.51 | -0.10 | -0.10 |
| 462.54 | -1.82 | -1.82 |
| 364.41 | -2.54 | -2.54 |
| 314.37 | -1.15 | -1.15 |
| 307.36 | -2.62 | -2.62 |
| 300.34 | -1.19 | -1.19 |
| 387.44 | -0.70 | -0.70 |
| 343.39 | -0.37 | -0.37 |
| 395.53 | -0.01 | -0.01 |
| 336.38 | 0.03 | 0.03 |
| 398.47 | 0.29 | 0.29 |
| 229.26 | -0.77 | -0.77 |
| 448.51 | -1.25 | -1.25 |
| 433.30 | -0.95 | -0.95 |
| 411.23 | -0.30 | -0.30 |
| 364.23 | -0.14 | -0.14 |
| 229.26 | -0.77 | -0.77 |
| 285.33 | -0.90 | -0.90 |
| 285.33 | -0.90 | -0.90 |
| 319.77 | -0.25 | -0.25 |
| 313.38 | -1.18 | -1.18 |
| 299.36 | -1.22 | -1.22 |
| 420.50 | -1.42 | -1.42 |
| 271.34 | -0.79 | -0.79 |
| 285.33 | -0.90 | -0.90 |
| 272.33 | -0.75 | -0.75 |
| 303.32 | -0.76 | -0.76 |
| 345.40 | -0.31 | -0.31 |
| 257.31 | -0.83 | -0.83 |
| 287.32 | -0.23 | -0.23 |
| 301.35 | 0.03 | 0.03 |
| 300.37 | 0.10 | 0.10 |
| 286.34 | -0.16 | -0.16 |
| 384.44 | 0.03 | 0.03 |
| 258.30 | -0.80 | -0.80 |
| 322.35 | -0.24 | -0.24 |
| 324.45 | 0.61 | 0.61 |
| 383.52 | 0.09 | 0.09 |
| 381.50 | -0.19 | -0.19 |
| 437.57 | -0.32 | -0.32 |
| 438.55 | -1.07 | -1.07 |