ID: ALA659806
Type: Functional
Description: In vivo beta adrenergic blocking potency was determined by inhibition of tachycardia produced by isoproterenol (0.2 mg/kg iv) in cat preparation
Organism: Felis catus
Bioactivity
Activity Types for Assay ALA659806
ED50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
259.35 | 2.58 | 2.58 |
266.34 | 1.38 | 1.38 |
387.44 | 1.62 | 1.62 |
294.39 | 1.10 | 1.10 |
280.37 | 0.79 | 0.79 |
280.37 | 0.93 | 0.93 |
238.29 | -0.24 | -0.24 |
316.42 | 0.35 | 0.35 |
409.46 | 1.29 | 1.29 |
350.44 | 0.99 | 0.99 |
388.86 | 2.36 | 2.36 |
384.44 | 1.72 | 1.72 |
359.43 | 1.85 | 1.85 |
343.43 | 2.15 | 2.15 |
358.44 | 1.38 | 1.38 |
359.43 | 1.85 | 1.85 |
369.42 | 1.08 | 1.08 |
373.41 | 1.28 | 1.28 |
342.44 | 1.76 | 1.76 |
373.41 | 1.28 | 1.28 |
397.30 | 2.68 | 2.68 |
362.86 | 2.03 | 2.03 |
291.35 | 0.41 | 0.41 |
266.34 | 0.54 | 0.54 |
306.28 | 0.69 | 0.69 |
314.81 | 1.44 | 1.44 |
350.85 | 1.45 | 1.45 |
454.50 | 1.34 | 1.34 |
406.87 | 2.36 | 2.36 |
474.92 | 1.65 | 1.65 |
485.47 | 0.90 | 0.90 |
472.52 | 1.30 | 1.30 |
483.50 | 0.87 | 0.87 |
461.47 | 2.04 | 2.04 |
445.47 | 2.48 | 2.48 |
347.42 | 1.84 | 1.84 |
482.49 | 1.22 | 1.22 |
358.35 | -0.88 | -0.88 |
427.45 | 1.05 | 1.05 |
372.43 | 1.71 | 1.71 |