Binding affinity was determined by displacement of [3H]P1075 from its binding sites in canine cardiac membranes

Basic Information

ID: ALA660002

Type: Binding

Description: Binding affinity was determined by displacement of [3H]P1075 from its binding sites in canine cardiac membranes

Format: BAO_0000249

Organism: Canis lupus familiaris

Tissue: Heart

Subcellular Fraction: Membrane

Target: Sulfonylurea receptor 2, Kir6.2(ALA2095198)

Document: ALA1131338

Binding affinity was determined by displacement of [3H]P1075 from its binding sites in canine cardiac membranes: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA660002

Total(16)

Parent Molecular Weight	ALogP	Polar Surface Area
494.01	3.64	3.64
286.33	1.75	1.75
231.30	2.11	2.11
269.35	2.83	2.83
199.22	1.03	1.03
227.27	1.81	1.81
241.30	2.20	2.20
255.32	2.59	2.59
377.51	2.89	2.89
269.35	2.83	2.83
244.34	2.96	2.96
356.21	3.32	3.32
377.51	2.89	2.89
397.22	4.26	4.26
245.33	2.35	2.35

Parent Molecular Weight

ALogP

Polar Surface Area

494.01

3.64

286.33

1.75

231.30

2.11

269.35

2.83

199.22

1.03

227.27

1.81

241.30

2.20

255.32

2.59

377.51

2.89

269.35

2.83

244.34

2.96

356.21

3.32

377.51

2.89

397.22

4.26

245.33

2.35

Binding affinity was determined by displacement of [3H]P1075 from its binding sites in canine cardiac membranes

Basic Information

Activity Charts

Compound Summary