Basic Information
ID: ALA660279
Type: Binding
Description: Inhibitory activity against Trypanosoma cruzi cathepsin L-like protease (cruzain) was determined using purified recombinant protein
Organism: Trypanosoma cruzi
Activity Charts
Bioactivity
Activity Types for Assay ALA660279
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 273.28 | 2.98 | 2.98 |
| 308.13 | 2.71 | 2.71 |
| 314.25 | 3.46 | 3.46 |
| 300.23 | 3.07 | 3.07 |
| 256.10 | 1.84 | 1.84 |
| 287.31 | 3.23 | 3.23 |
| 287.39 | 3.21 | 3.21 |
| 286.20 | 2.81 | 2.81 |
| 272.17 | 2.42 | 2.42 |
| 312.24 | 3.16 | 3.16 |
| 298.21 | 2.77 | 2.77 |
| 366.28 | 4.23 | 4.23 |
| 288.20 | 3.51 | 3.51 |
| 274.18 | 2.65 | 2.65 |
| 253.76 | 2.86 | 2.86 |
| 288.21 | 2.65 | 2.65 |
| 239.73 | 1.99 | 1.99 |
| 246.10 | 2.39 | 2.39 |
| 245.20 | 2.10 | 2.10 |
| 211.65 | 1.73 | 1.73 |
| 225.29 | 2.18 | 2.18 |
| 275.30 | 3.06 | 3.06 |
| 272.17 | 2.42 | 2.42 |
| 263.68 | 2.60 | 2.60 |
| 263.68 | 2.60 | 2.60 |
| 225.68 | 2.12 | 2.12 |
| 259.23 | 2.49 | 2.49 |
| 258.14 | 2.03 | 2.03 |
| 270.13 | 2.23 | 2.23 |
| 364.27 | 3.53 | 3.53 |
| 261.27 | 2.67 | 2.67 |
| 247.25 | 2.49 | 2.49 |
| 430.29 | 5.98 | 5.98 |
| 397.34 | 2.07 | 2.07 |
| 329.27 | 3.69 | 3.69 |
| 327.23 | 3.51 | 3.51 |
| 260.12 | 2.78 | 2.78 |
| 428.28 | 5.27 | 5.27 |
| 360.28 | 4.26 | 4.26 |
| 383.83 | 5.17 | 5.17 |
| 326.26 | 3.55 | 3.55 |
| 368.34 | 4.73 | 4.73 |
| 394.73 | 4.91 | 4.91 |
| 227.72 | 2.31 | 2.31 |
| 398.37 | 2.34 | 2.34 |
| 362.30 | 4.96 | 4.96 |
| 298.21 | 2.97 | 2.97 |
| 284.18 | 2.10 | 2.10 |
| 278.20 | 2.48 | 2.48 |
| 233.75 | 2.37 | 2.37 |
| 262.17 | 2.96 | 2.96 |
| 248.14 | 2.57 | 2.57 |
| 285.40 | 2.73 | 2.73 |
| 278.38 | 1.49 | 1.49 |
| 328.28 | 3.85 | 3.85 |
| 241.75 | 2.70 | 2.70 |
| 259.33 | 2.43 | 2.43 |
| 272.38 | 2.48 | 2.48 |
| 223.30 | 1.66 | 1.66 |
| 276.19 | 3.35 | 3.35 |
| 276.19 | 3.35 | 3.35 |
| 207.30 | 2.05 | 2.05 |
| 232.31 | 1.76 | 1.76 |
| 343.30 | 4.08 | 4.08 |
| 237.33 | 2.05 | 2.05 |
| 241.75 | 2.70 | 2.70 |
| 279.75 | 3.18 | 3.18 |
| 286.20 | 2.81 | 2.81 |
| 324.20 | 3.29 | 3.29 |
| 247.25 | 2.49 | 2.49 |
| 248.14 | 2.57 | 2.57 |
| 248.14 | 2.57 | 2.57 |
| 315.24 | 3.51 | 3.51 |
| 333.36 | 2.75 | 2.75 |
| 308.39 | 1.30 | 1.30 |
| 279.75 | 3.18 | 3.18 |
| 275.33 | 2.53 | 2.53 |
| 225.27 | 0.57 | 0.57 |