Basic Information
ID: ALA662724
Type: Binding
Description: Inhibitory activity against Human carbonic anhydrase I
Activity Charts
Bioactivity
Activity Types for Assay ALA662724
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 200.26 | -0.16 | -0.16 |
| 285.73 | -0.78 | -0.78 |
| 230.27 | 0.65 | 0.65 |
| 201.25 | -0.13 | -0.13 |
| 187.22 | -0.17 | -0.17 |
| 172.21 | -0.08 | -0.08 |
| 194.24 | -1.39 | -1.39 |
| 180.21 | -1.23 | -1.23 |
| 172.21 | -0.08 | -0.08 |
| 298.11 | 0.52 | 0.52 |
| 305.16 | 0.29 | 0.29 |
| 258.32 | 1.34 | 1.34 |
| 251.10 | 0.68 | 0.68 |
| 190.20 | 0.06 | 0.06 |
| 236.28 | -1.42 | -1.42 |
| 222.25 | -0.86 | -0.86 |
| 186.24 | -0.21 | -0.21 |
| 206.65 | 0.57 | 0.57 |
| 187.22 | -0.38 | -0.38 |
| 172.21 | -0.08 | -0.08 |
| 251.29 | -1.53 | -1.53 |
| 320.18 | -0.13 | -0.13 |
| 718.76 | -1.43 | -1.43 |
| 892.97 | -0.45 | -0.45 |
| 928.79 | -3.68 | -3.68 |
| 953.53 | -1.07 | -1.07 |
| 661.07 | -3.18 | -3.18 |
| 695.51 | -2.53 | -2.53 |
| 673.44 | -1.88 | -1.88 |
| 804.86 | -0.48 | -0.48 |
| 802.89 | -0.42 | -0.42 |
| 461.45 | -2.37 | -2.37 |
| 626.63 | -4.13 | -4.13 |
| 569.58 | -4.20 | -4.20 |
| 555.55 | -3.63 | -3.63 |
| 997.68 | -2.37 | -2.37 |
| 446.44 | -1.87 | -1.87 |
| 359.40 | -1.32 | -1.32 |
| 315.35 | -1.33 | -1.33 |
| 360.35 | -1.75 | -1.75 |
| 432.48 | -0.87 | -0.87 |
| 388.43 | -0.89 | -0.89 |
| 330.37 | -1.46 | -1.46 |
| 345.38 | -1.36 | -1.36 |
| 359.36 | -1.58 | -1.58 |
| 846.91 | -4.92 | -4.92 |
| 387.44 | -0.85 | -0.85 |
| 409.45 | -3.11 | -3.11 |
| 859.53 | -0.76 | -0.76 |
| 770.63 | -0.97 | -0.97 |
| 737.72 | -2.00 | -2.00 |
| 746.81 | -1.34 | -1.34 |
| 229.29 | 0.53 | 0.53 |
| 556.58 | -3.55 | -3.55 |
| 424.23 | -0.49 | -0.49 |
| 344.39 | -1.79 | -1.79 |
| 345.38 | -1.96 | -1.96 |
| 600.63 | -1.67 | -1.67 |
| 701.74 | -2.28 | -2.28 |
| 718.77 | -2.63 | -2.63 |
| 688.74 | -1.63 | -1.63 |
| 330.37 | -1.46 | -1.46 |
| 552.53 | -1.70 | -1.70 |
| 744.85 | -2.19 | -2.19 |
| 716.79 | -2.28 | -2.28 |
| 503.52 | -1.26 | -1.26 |
| 817.86 | -1.13 | -1.13 |
| 721.78 | -4.51 | -4.51 |
| 804.86 | -0.48 | -0.48 |
| 714.79 | -0.45 | -0.45 |
| 758.80 | -4.95 | -4.95 |
| 562.60 | -2.12 | -2.12 |
| 548.57 | -2.16 | -2.16 |
| 525.52 | -3.51 | -3.51 |
| 409.26 | -0.70 | -0.70 |
| 591.62 | -1.23 | -1.23 |
| 613.63 | -3.48 | -3.48 |
| 358.42 | -1.74 | -1.74 |
| 701.74 | -2.28 | -2.28 |
| 759.81 | -1.99 | -1.99 |
| 468.47 | -3.59 | -3.59 |
| 640.46 | 2.39 | 2.39 |
| 549.01 | 2.43 | 2.43 |
| 532.55 | 1.92 | 1.92 |
| 593.46 | 2.54 | 2.54 |
| 731.76 | -2.07 | -2.07 |
| 716.75 | -0.51 | -0.51 |
| 630.66 | -2.66 | -2.66 |
| 547.54 | -2.48 | -2.48 |
| 658.71 | -1.37 | -1.37 |
| 630.65 | -1.46 | -1.46 |
| 549.56 | -2.33 | -2.33 |
| 454.44 | -3.02 | -3.02 |
| 543.60 | 1.93 | 1.93 |
| 536.59 | 0.07 | 0.07 |
| 464.43 | -1.73 | -1.73 |
| 504.50 | -1.29 | -1.29 |
| 562.55 | -2.38 | -2.38 |
| 446.44 | -1.87 | -1.87 |
| 446.44 | -1.87 | -1.87 |
| 480.88 | -1.22 | -1.22 |
| 474.49 | -2.15 | -2.15 |
| 656.74 | -2.23 | -2.23 |
| 628.69 | -2.31 | -2.31 |
| 688.74 | -1.63 | -1.63 |
| 688.74 | -1.63 | -1.63 |
| 563.58 | -1.69 | -1.69 |
| 649.66 | -1.89 | -1.89 |
| 626.44 | -1.72 | -1.72 |
| 745.80 | -5.71 | -5.71 |
| 701.74 | -2.28 | -2.28 |
| 600.63 | -1.67 | -1.67 |
| 757.63 | -0.33 | -0.33 |
| 724.72 | -1.36 | -1.36 |
| 576.58 | -2.34 | -2.34 |
| 514.56 | 1.78 | 1.78 |
| 575.60 | -2.76 | -2.76 |
| 547.54 | -2.48 | -2.48 |
| 547.54 | -2.48 | -2.48 |
| 572.62 | 2.36 | 2.36 |
| 345.33 | -1.26 | -1.26 |
| 345.33 | -1.26 | -1.26 |
| 514.56 | 1.78 | 1.78 |
| 514.56 | 1.78 | 1.78 |
| 616.64 | -3.97 | -3.97 |
| 644.70 | -5.10 | -5.10 |
| 366.38 | -2.70 | -2.70 |
| 460.47 | -2.19 | -2.19 |
| 984.68 | -1.73 | -1.73 |
| 940.53 | -0.43 | -0.43 |
| 302.31 | -0.95 | -0.95 |
| 389.41 | -0.46 | -0.46 |
| 344.37 | -0.44 | -0.44 |
| 367.37 | -2.97 | -2.97 |
| 353.34 | -2.40 | -2.40 |
| 309.33 | -2.77 | -2.77 |
| 458.86 | -1.96 | -1.96 |
| 295.30 | -2.20 | -2.20 |
| 366.19 | -0.29 | -0.29 |
| 846.53 | -0.11 | -0.11 |
| 305.29 | -0.91 | -0.91 |
| 493.30 | -1.30 | -1.30 |
| 471.23 | -0.65 | -0.65 |
| 400.82 | -1.75 | -1.75 |
| 413.19 | -0.45 | -0.45 |
| 321.74 | -0.40 | -0.40 |
| 534.54 | -1.84 | -1.84 |
| 534.54 | -1.84 | -1.84 |
| 534.54 | -1.84 | -1.84 |
| 287.30 | -1.05 | -1.05 |
| 435.27 | -1.10 | -1.10 |
| 581.99 | -1.83 | -1.83 |
| 565.53 | -2.34 | -2.34 |
| 379.78 | -0.60 | -0.60 |
| 363.32 | -1.12 | -1.12 |
| 827.68 | -3.07 | -3.07 |
| 636.66 | -1.24 | -1.24 |
| 592.60 | -1.26 | -1.26 |
| 542.55 | -2.98 | -2.98 |
| 287.30 | -1.05 | -1.05 |
| 287.30 | -1.05 | -1.05 |
| 549.56 | -1.73 | -1.73 |
| 648.07 | -2.54 | -2.54 |
| 757.84 | -2.84 | -2.84 |
| 729.79 | -2.93 | -2.93 |
| 669.52 | -0.36 | -0.36 |
| 636.61 | -1.39 | -1.39 |
| 478.34 | -1.51 | -1.51 |
| 896.57 | -1.76 | -1.76 |
| 852.42 | -0.46 | -0.46 |
| 758.42 | -0.14 | -0.14 |
| 613.44 | -1.07 | -1.07 |
| 704.75 | -3.93 | -3.93 |
| 682.51 | -1.88 | -1.88 |
| 461.45 | -1.76 | -1.76 |
| 731.77 | -3.27 | -3.27 |
| 559.96 | -2.57 | -2.57 |
| 529.57 | 1.89 | 1.89 |
| 815.89 | -1.06 | -1.06 |
| 859.90 | -5.57 | -5.57 |
| 364.81 | -0.81 | -0.81 |
| 348.36 | -1.32 | -1.32 |
| 274.32 | 0.31 | 0.31 |
| 373.39 | -1.54 | -1.54 |
| 456.26 | -0.86 | -0.86 |
| 732.80 | -5.07 | -5.07 |
| 660.44 | -1.23 | -1.23 |
| 600.63 | -1.67 | -1.67 |
| 568.99 | -1.18 | -1.18 |
| 548.55 | -1.28 | -1.28 |
| 542.61 | 1.50 | 1.50 |
| 528.59 | 1.46 | 1.46 |
| 529.58 | 1.29 | 1.29 |
| 302.31 | -1.55 | -1.55 |
| 605.60 | -1.91 | -1.91 |
| 571.64 | 2.39 | 2.39 |
| 593.64 | 0.14 | 0.14 |
| 604.62 | -1.87 | -1.87 |
| 561.57 | -2.81 | -2.81 |
| 572.33 | -1.27 | -1.27 |
| 594.41 | -1.92 | -1.92 |
| 525.33 | -1.11 | -1.11 |
| 562.56 | -2.98 | -2.98 |
| 522.57 | 0.63 | 0.63 |
| 330.37 | -1.46 | -1.46 |
| 374.37 | -1.11 | -1.11 |
| 360.34 | -1.15 | -1.15 |
| 345.36 | -0.48 | -0.48 |
| 352.40 | -3.18 | -3.18 |
| 338.37 | -2.61 | -2.61 |
| 915.79 | -3.03 | -3.03 |
| 443.89 | -2.16 | -2.16 |
| 345.33 | -1.26 | -1.26 |
| 316.34 | -0.91 | -0.91 |
| 628.09 | 1.08 | 1.08 |
| 662.53 | 1.74 | 1.74 |
| 616.67 | 2.37 | 2.37 |
| 424.42 | -2.90 | -2.90 |
| 301.32 | -1.38 | -1.38 |
| 447.45 | -0.66 | -0.66 |
| 403.39 | -0.68 | -0.68 |
| 402.41 | -0.65 | -0.65 |
| 475.48 | -1.72 | -1.72 |
| 324.45 | 0.61 | 0.61 |
| 754.13 | -1.63 | -1.63 |
| 810.24 | -2.19 | -2.19 |
| 782.18 | -2.28 | -2.28 |
| 722.13 | -2.23 | -2.23 |
| 694.08 | -2.31 | -2.31 |
| 811.19 | -5.71 | -5.71 |
| 666.02 | -1.67 | -1.67 |
| 682.03 | -3.97 | -3.97 |
| 710.09 | -5.10 | -5.10 |
| 823.23 | -2.84 | -2.84 |
| 770.14 | -3.93 | -3.93 |
| 798.19 | -5.07 | -5.07 |
| 678.17 | ||
| 779.28 | ||
| 766.28 | ||
| 781.12 | -4.58 | -4.58 |
| 765.11 | -2.28 | -2.28 |
| 793.16 | -2.93 | -2.93 |