Basic Information
ID: ALA666140
Type: Binding
Description: Inhibitory activity against human cyclin-dependent kinase 1 (CDK1)
Activity Charts
Bioactivity
Activity Types for Assay ALA666140
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 442.24 | 3.54 | 3.54 |
| 385.47 | 3.25 | 3.25 |
| 383.45 | 3.13 | 3.13 |
| 344.40 | 1.66 | 1.66 |
| 395.24 | 1.86 | 1.86 |
| 361.34 | 1.01 | 1.01 |
| 373.42 | 1.71 | 1.71 |
| 509.54 | 2.05 | 2.05 |
| 345.38 | 1.23 | 1.23 |
| 387.42 | 1.92 | 1.92 |
| 445.50 | 0.85 | 0.85 |
| 436.49 | 2.59 | 2.59 |
| 382.41 | 1.49 | 1.49 |
| 357.36 | 0.37 | 0.37 |
| 450.48 | 1.43 | 1.43 |
| 450.48 | 1.43 | 1.43 |
| 434.48 | 2.98 | 2.98 |
| 467.51 | 1.12 | 1.12 |
| 387.42 | 0.80 | 0.80 |
| 453.48 | 0.80 | 0.80 |
| 359.37 | 0.20 | 0.20 |
| 399.47 | 2.97 | 2.97 |
| 408.44 | 2.89 | 2.89 |
| 390.81 | 1.63 | 1.63 |
| 415.47 | 2.55 | 2.55 |
| 373.39 | 1.53 | 1.53 |
| 374.42 | 1.89 | 1.89 |
| 356.37 | 0.98 | 0.98 |
| 375.37 | 1.32 | 1.32 |
| 359.36 | 1.44 | 1.44 |
| 360.40 | 1.50 | 1.50 |
| 396.41 | 0.35 | 0.35 |
| 370.43 | 2.53 | 2.53 |
| 395.42 | -0.25 | -0.25 |
| 372.45 | 2.30 | 2.30 |
| 394.43 | 0.51 | 0.51 |
| 344.40 | 1.66 | 1.66 |
| 358.42 | 2.23 | 2.23 |
| 380.81 | 1.76 | 1.76 |
| 358.42 | 1.81 | 1.81 |
| 364.81 | 2.06 | 2.06 |
| 331.36 | 0.68 | 0.68 |
| 361.34 | 1.01 | 1.01 |
| 382.40 | 2.39 | 2.39 |
| 396.43 | 2.78 | 2.78 |
| 363.83 | 2.70 | 2.70 |
| 363.83 | 2.78 | 2.78 |
| 383.39 | 1.76 | 1.76 |
| 343.41 | 2.36 | 2.36 |
| 350.79 | 1.76 | 1.76 |
| 329.38 | 2.13 | 2.13 |
| 315.35 | 1.74 | 1.74 |
| 329.38 | 2.05 | 2.05 |
| 346.37 | 1.11 | 1.11 |
| 316.34 | 1.10 | 1.10 |
| 395.24 | 1.86 | 1.86 |
| 330.37 | 1.41 | 1.41 |
| 332.34 | 0.81 | 0.81 |
| 408.44 | 2.89 | 2.89 |
| 345.38 | 1.23 | 1.23 |
| 442.24 | 1.71 | 1.71 |
| 334.33 | 1.24 | 1.24 |
| 372.45 | 2.40 | 2.40 |
| 359.37 | 0.20 | 0.20 |
| 366.40 | 2.29 | 2.29 |
| 367.39 | 1.65 | 1.65 |
| 358.42 | 2.23 | 2.23 |
| 329.38 | 2.00 | 2.00 |
| 401.47 | 2.11 | 2.11 |
| 393.42 | 3.18 | 3.18 |
| 398.47 | 3.35 | 3.35 |
| 357.40 | 1.26 | 1.26 |
| 449.52 | 3.90 | 3.90 |
| 421.48 | 2.28 | 2.28 |
| 372.43 | 2.35 | 2.35 |
| 462.56 | 4.18 | 4.18 |
| 414.47 | 2.53 | 2.53 |
| 448.53 | 4.50 | 4.50 |
| 386.46 | 2.61 | 2.61 |
| 416.48 | 1.97 | 1.97 |
| 400.49 | 2.95 | 2.95 |
| 386.48 | 1.93 | 1.93 |
| 576.70 | 3.02 | 3.02 |
| 562.67 | 2.68 | 2.68 |
| 466.55 | 2.95 | 2.95 |
| 476.58 | 5.12 | 5.12 |
| 463.54 | 3.92 | 3.92 |
| 414.47 | 1.87 | 1.87 |
| 400.49 | 2.75 | 2.75 |
| 386.46 | 2.49 | 2.49 |
| 430.51 | 2.11 | 2.11 |
| 460.54 | 1.99 | 1.99 |
| 371.44 | 3.10 | 3.10 |
| 500.59 | 4.07 | 4.07 |