Basic Information
ID: ALA666235
Type: Binding
Description: The concentration required to inhibit dihydrofolate reductase in rat liver
Tissue: Liver
Activity Charts
Bioactivity
Activity Types for Assay ALA666235
Log 1/C
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 353.23 | 3.27 | 3.27 |
| 335.39 | 3.24 | 3.24 |
| 319.39 | 4.22 | 4.22 |
| 259.31 | 1.07 | 1.07 |
| 289.34 | 1.05 | 1.05 |
| 350.40 | 2.78 | 2.78 |
| 285.27 | 1.89 | 1.89 |
| 231.30 | 1.18 | 1.18 |
| 231.30 | 1.18 | 1.18 |
| 247.30 | 0.88 | 0.88 |
| 273.38 | 2.17 | 2.17 |
| 247.30 | 0.88 | 0.88 |
| 303.39 | 4.52 | 4.52 |
| 235.27 | 1.01 | 1.01 |
| 235.27 | 1.01 | 1.01 |
| 338.22 | 4.38 | 4.38 |
| 337.24 | 4.25 | 4.25 |
| 177.23 | 1.50 | 1.50 |
| 285.27 | 1.89 | 1.89 |
| 369.23 | 2.93 | 2.93 |
| 296.17 | 1.63 | 1.63 |
| 217.28 | 0.87 | 0.87 |
| 290.32 | 1.26 | 1.26 |
| 351.39 | 2.90 | 2.90 |
| 259.31 | 1.07 | 1.07 |
| 343.17 | 1.48 | 1.48 |
| 369.23 | 2.93 | 2.93 |
| 289.34 | 1.05 | 1.05 |
| 296.36 | -0.48 | -0.48 |
| 370.22 | 3.06 | 3.06 |
| 296.17 | 1.63 | 1.63 |
| 336.34 | 3.96 | 3.96 |
| 386.25 | 3.05 | 3.05 |
| 352.51 | 5.51 | 5.51 |
| 334.40 | 3.11 | 3.11 |
| 337.24 | 4.25 | 4.25 |
| 367.45 | 3.49 | 3.49 |
| 361.33 | 2.74 | 2.74 |
| 319.39 | 4.22 | 4.22 |
| 376.25 | 3.67 | 3.67 |
| 318.41 | 4.10 | 4.10 |
| 296.36 | -0.48 | -0.48 |
| 334.21 | 3.71 | 3.71 |
| 336.44 | 4.93 | 4.93 |
| 175.20 | 0.38 | 0.38 |
| 319.39 | 3.53 | 3.53 |
| 335.46 | 4.81 | 4.81 |
| 335.46 | 4.81 | 4.81 |
| 335.39 | 3.20 | 3.20 |
| 194.62 | 1.45 | 1.45 |
| 251.72 | 1.53 | 1.53 |
| 273.38 | 2.17 | 2.17 |
| 275.31 | 0.66 | 0.66 |
| 336.44 | 4.89 | 4.89 |
| 343.17 | 1.48 | 1.48 |
| 320.37 | 3.52 | 3.52 |
| 230.27 | 1.24 | 1.24 |
| 230.27 | 1.24 | 1.24 |
| 200.25 | 1.23 | 1.23 |
| 234.69 | 1.89 | 1.89 |
| 214.27 | 1.54 | 1.54 |
| 260.30 | 1.25 | 1.25 |
| 266.31 | 1.80 | 1.80 |
| 454.45 | 0.27 | 0.27 |
| 452.47 | 1.76 | 1.76 |
| 130.15 | 1.63 | 1.63 |
| 216.24 | 0.94 | 0.94 |
| 300.36 | 2.28 | 2.28 |
| 265.32 | 2.41 | 2.41 |
| 276.30 | 0.95 | 0.95 |
| 162.15 | 0.22 | 0.22 |
| 281.32 | 2.11 | 2.11 |
| 368.65 | 4.37 | 4.37 |
| 299.76 | 3.06 | 3.06 |
| 379.42 | 2.82 | 2.82 |
| 279.35 | 2.71 | 2.71 |
| 335.20 | 3.11 | 3.11 |
| 294.74 | 1.90 | 1.90 |
| 355.40 | 2.43 | 2.43 |
| 318.33 | 1.04 | 1.04 |
| 303.37 | 3.11 | 3.11 |
| 358.23 | 4.10 | 4.10 |
| 213.24 | 1.29 | 1.29 |
| 283.31 | 2.55 | 2.55 |
| 281.32 | 2.11 | 2.11 |
| 281.32 | 2.11 | 2.11 |
| 299.76 | 3.06 | 3.06 |
| 279.35 | 2.71 | 2.71 |
| 271.31 | 1.86 | 1.86 |
| 270.32 | 1.74 | 1.74 |
| 285.33 | 2.17 | 2.17 |
| 279.35 | 2.71 | 2.71 |
| 284.35 | 1.88 | 1.88 |
| 302.33 | 1.45 | 1.45 |
| 344.22 | 3.17 | 3.17 |
| 348.24 | 4.02 | 4.02 |
| 290.32 | 0.74 | 0.74 |
| 344.22 | 3.17 | 3.17 |
| 344.22 | 3.17 | 3.17 |
| 358.24 | 3.48 | 3.48 |
| 285.33 | 2.00 | 2.00 |
| 312.40 | 2.86 | 2.86 |
| 279.35 | 2.71 | 2.71 |
| 315.38 | 3.72 | 3.72 |
| 299.76 | 3.06 | 3.06 |
| 349.83 | 4.37 | 4.37 |
| 284.35 | 2.04 | 2.04 |