Basic Information
ID: ALA666238
Type: Binding
Description: Concentration required for inhibition of rat liver dihydrofolate reductase (DHFR)
Activity Charts
Bioactivity
Activity Types for Assay ALA666238
Log 1/C
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 334.40 | 3.11 | 3.11 |
| 353.23 | 3.27 | 3.27 |
| 335.39 | 3.24 | 3.24 |
| 319.39 | 4.22 | 4.22 |
| 350.40 | 2.78 | 2.78 |
| 350.40 | 2.78 | 2.78 |
| 303.39 | 4.52 | 4.52 |
| 327.77 | 2.63 | 2.63 |
| 389.48 | 3.99 | 3.99 |
| 178.24 | 0.77 | 0.77 |
| 203.20 | 1.29 | 1.29 |
| 338.22 | 4.38 | 4.38 |
| 337.24 | 4.25 | 4.25 |
| 229.07 | 2.10 | 2.10 |
| 393.42 | 3.28 | 3.28 |
| 376.25 | 2.96 | 2.96 |
| 177.23 | 1.50 | 1.50 |
| 396.67 | 3.94 | 3.94 |
| 341.80 | 2.94 | 2.94 |
| 369.23 | 2.93 | 2.93 |
| 351.39 | 2.90 | 2.90 |
| 395.77 | 3.65 | 3.65 |
| 376.25 | 3.59 | 3.59 |
| 386.25 | 3.05 | 3.05 |
| 369.23 | 2.93 | 2.93 |
| 289.34 | 1.05 | 1.05 |
| 174.21 | 1.10 | 1.10 |
| 370.22 | 3.06 | 3.06 |
| 336.34 | 3.96 | 3.96 |
| 164.21 | 0.52 | 0.52 |
| 175.19 | 1.23 | 1.23 |
| 195.61 | 1.57 | 1.57 |
| 386.25 | 3.05 | 3.05 |
| 412.66 | 3.77 | 3.77 |
| 334.40 | 3.11 | 3.11 |
| 333.30 | -0.16 | -0.16 |
| 337.24 | 4.25 | 4.25 |
| 367.45 | 3.49 | 3.49 |
| 185.19 | 0.67 | 0.67 |
| 160.18 | 0.79 | 0.79 |
| 239.08 | 1.56 | 1.56 |
| 175.19 | 1.23 | 1.23 |
| 361.33 | 2.74 | 2.74 |
| 177.23 | 1.50 | 1.50 |
| 389.41 | 0.80 | 0.80 |
| 348.32 | 0.27 | 0.27 |
| 390.40 | 0.92 | 0.92 |
| 355.83 | 3.33 | 3.33 |
| 319.39 | 4.22 | 4.22 |
| 376.25 | 3.67 | 3.67 |
| 273.52 | 2.21 | 2.21 |
| 332.43 | 4.24 | 4.24 |
| 229.16 | 1.94 | 1.94 |
| 161.16 | 0.51 | 0.51 |
| 318.41 | 4.10 | 4.10 |
| 428.92 | 2.81 | 2.81 |
| 334.29 | -0.03 | -0.03 |
| 145.16 | 1.21 | 1.21 |
| 334.21 | 3.71 | 3.71 |
| 174.21 | 1.10 | 1.10 |
| 336.44 | 4.93 | 4.93 |
| 362.22 | 3.28 | 3.28 |
| 431.57 | 5.01 | 5.01 |
| 351.39 | 2.90 | 2.90 |
| 357.42 | 3.44 | 3.44 |
| 377.83 | 3.78 | 3.78 |
| 347.33 | 0.15 | 0.15 |
| 406.67 | 3.39 | 3.39 |
| 175.20 | 0.38 | 0.38 |
| 362.22 | 3.28 | 3.28 |
| 319.39 | 3.53 | 3.53 |
| 393.83 | 3.62 | 3.62 |
| 373.42 | 3.27 | 3.27 |
| 404.42 | 1.23 | 1.23 |
| 335.46 | 4.81 | 4.81 |
| 341.80 | 3.02 | 3.02 |
| 343.39 | 3.13 | 3.13 |
| 341.80 | 3.19 | 3.19 |
| 403.44 | 1.11 | 1.11 |
| 375.35 | 3.30 | 3.30 |
| 361.33 | 2.99 | 2.99 |
| 189.22 | 0.25 | 0.25 |
| 335.46 | 4.81 | 4.81 |
| 335.39 | 3.20 | 3.20 |
| 194.62 | 1.45 | 1.45 |
| 179.22 | 0.89 | 0.89 |
| 319.39 | 4.22 | 4.22 |
| 161.16 | 0.92 | 0.92 |
| 165.20 | 0.64 | 0.64 |
| 146.15 | 0.92 | 0.92 |
| 312.38 | 4.12 | 4.12 |
| 336.44 | 4.89 | 4.89 |
| 362.22 | 3.03 | 3.03 |
| 343.39 | 2.88 | 2.88 |
| 406.67 | 3.39 | 3.39 |
| 314.39 | 3.73 | 3.73 |
| 316.82 | 3.74 | 3.74 |
| 312.38 | 4.12 | 4.12 |
| 194.63 | 1.45 | 1.45 |
| 209.64 | 1.03 | 1.03 |
| 320.37 | 3.52 | 3.52 |
| 454.45 | 0.27 | 0.27 |
| 162.15 | 0.22 | 0.22 |